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Joseph D. Murphy
Joseph D. Murphy
Senior Scientist, BioNTech US
Verified email at urmc.rochester.edu - Homepage
Title
Cited by
Cited by
Year
Stereotactic body radiation and interleukin-12 combination therapy eradicates pancreatic tumors by repolarizing the immune microenvironment
BN Mills, KA Connolly, J Ye, JD Murphy, TP Uccello, BJ Han, T Zhao, ...
Cell reports 29 (2), 406-421. e5, 2019
782019
Modulation of the human pancreatic ductal adenocarcinoma immune microenvironment by stereotactic body radiotherapy
BN Mills, H Qiu, MG Drage, C Chen, JS Mathew, J Garrett-Larsen, J Ye, ...
Clinical Cancer Research 28 (1), 150-162, 2022
442022
Assessing the magnitude of immunogenic cell death following chemotherapy and irradiation reveals a new strategy to treat pancreatic cancer
J Ye, BN Mills, T Zhao, BJ Han, JD Murphy, AP Patel, CJ Johnston, ...
Cancer immunology research 8 (1), 94-107, 2020
382020
Toll-like receptor 7/8 agonist R848 alters the immune tumor microenvironment and enhances SBRT-induced antitumor efficacy in murine models of pancreatic cancer
J Ye, BN Mills, SS Qin, J Garrett-Larsen, JD Murphy, TP Uccello, BJ Han, ...
Journal for Immunotherapy of cancer 10 (7), 2022
372022
Combination of NKG2A and PD-1 blockade improves radiotherapy response in radioresistant tumors
NG Battaglia, JD Murphy, TP Uccello, A Hughson, NW Gavras, JJ Caldon, ...
The Journal of Immunology 209 (3), 629-640, 2022
172022
Microspheres encapsulating immunotherapy agents target the tumor-draining lymph node in pancreatic ductal adenocarcinoma
BJ Han, JD Murphy, S Qin, J Ye, TP Uccello, J Garrett-Larsen, BA Belt, ...
Immunological investigations 49 (7), 808-823, 2020
112020
Development of an orthotopic murine model of rectal cancer in conjunction with targeted short-course radiation therapy
TP Uccello, SA Kintzel, BN Mills, JD Murphy, J Garrett-Larsen, ...
Advances in Radiation Oncology 7 (2), 100867, 2022
92022
Increased myocellular lipid and IGFBP‐3 expression in a pre‐clinical model of pancreatic cancer‐related skeletal muscle wasting
CL Cole, JF Bachman, J Ye, J Murphy, SA Gerber, CA Beck, BF Boyce, ...
Journal of Cachexia, Sarcopenia and Muscle 12 (3), 731-745, 2021
82021
Radiation therapy exacerbates tumor-promoting innervation and nerve signaling in rectal cancer
TP Uccello, ML Lesch, NA Ullman, SA Kintzel, LB Gradzewicz, ...
International Journal of Radiation Oncology* Biology* Physics 115 (3), 733-745, 2023
22023
Investigating the tumor-immune microenvironment in an autochthonous murine model of cholangiocarcinoma.
BJ Han, LI Ruffolo, KM Jackson, BA Belt, N Figueroa, JD Murphy, ...
Journal of Clinical Oncology 37 (8_suppl), 53-53, 2019
22019
Local Delivery of SBRT and IL12 by mRNA Technology Overcomes Immunosuppressive Barriers to Eliminate Pancreatic Cancer
AL Hughson, G Hannon, NA Salama, TG Vrooman, CA Stockwell, ...
bioRxiv, 2023.10. 30.564833, 2023
12023
New insights into the responder/nonresponder divide in rectal cancer: Damage-induced Type I IFNs dictate treatment efficacy and can be targeted to enhance radiotherapy
S Gerber, T Uccello, M Lesch, S Kintzel, L Gradzewicz, L Lamrous, ...
Research Square, 2023
2023
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