Stereotactic body radiation and interleukin-12 combination therapy eradicates pancreatic tumors by repolarizing the immune microenvironment BN Mills, KA Connolly, J Ye, JD Murphy, TP Uccello, BJ Han, T Zhao, ... Cell reports 29 (2), 406-421. e5, 2019 | 78 | 2019 |
Modulation of the human pancreatic ductal adenocarcinoma immune microenvironment by stereotactic body radiotherapy BN Mills, H Qiu, MG Drage, C Chen, JS Mathew, J Garrett-Larsen, J Ye, ... Clinical Cancer Research 28 (1), 150-162, 2022 | 44 | 2022 |
Assessing the magnitude of immunogenic cell death following chemotherapy and irradiation reveals a new strategy to treat pancreatic cancer J Ye, BN Mills, T Zhao, BJ Han, JD Murphy, AP Patel, CJ Johnston, ... Cancer immunology research 8 (1), 94-107, 2020 | 38 | 2020 |
Toll-like receptor 7/8 agonist R848 alters the immune tumor microenvironment and enhances SBRT-induced antitumor efficacy in murine models of pancreatic cancer J Ye, BN Mills, SS Qin, J Garrett-Larsen, JD Murphy, TP Uccello, BJ Han, ... Journal for Immunotherapy of cancer 10 (7), 2022 | 37 | 2022 |
Combination of NKG2A and PD-1 blockade improves radiotherapy response in radioresistant tumors NG Battaglia, JD Murphy, TP Uccello, A Hughson, NW Gavras, JJ Caldon, ... The Journal of Immunology 209 (3), 629-640, 2022 | 17 | 2022 |
Microspheres encapsulating immunotherapy agents target the tumor-draining lymph node in pancreatic ductal adenocarcinoma BJ Han, JD Murphy, S Qin, J Ye, TP Uccello, J Garrett-Larsen, BA Belt, ... Immunological investigations 49 (7), 808-823, 2020 | 11 | 2020 |
Development of an orthotopic murine model of rectal cancer in conjunction with targeted short-course radiation therapy TP Uccello, SA Kintzel, BN Mills, JD Murphy, J Garrett-Larsen, ... Advances in Radiation Oncology 7 (2), 100867, 2022 | 9 | 2022 |
Increased myocellular lipid and IGFBP‐3 expression in a pre‐clinical model of pancreatic cancer‐related skeletal muscle wasting CL Cole, JF Bachman, J Ye, J Murphy, SA Gerber, CA Beck, BF Boyce, ... Journal of Cachexia, Sarcopenia and Muscle 12 (3), 731-745, 2021 | 8 | 2021 |
Radiation therapy exacerbates tumor-promoting innervation and nerve signaling in rectal cancer TP Uccello, ML Lesch, NA Ullman, SA Kintzel, LB Gradzewicz, ... International Journal of Radiation Oncology* Biology* Physics 115 (3), 733-745, 2023 | 2 | 2023 |
Investigating the tumor-immune microenvironment in an autochthonous murine model of cholangiocarcinoma. BJ Han, LI Ruffolo, KM Jackson, BA Belt, N Figueroa, JD Murphy, ... Journal of Clinical Oncology 37 (8_suppl), 53-53, 2019 | 2 | 2019 |
Local Delivery of SBRT and IL12 by mRNA Technology Overcomes Immunosuppressive Barriers to Eliminate Pancreatic Cancer AL Hughson, G Hannon, NA Salama, TG Vrooman, CA Stockwell, ... bioRxiv, 2023.10. 30.564833, 2023 | 1 | 2023 |
New insights into the responder/nonresponder divide in rectal cancer: Damage-induced Type I IFNs dictate treatment efficacy and can be targeted to enhance radiotherapy S Gerber, T Uccello, M Lesch, S Kintzel, L Gradzewicz, L Lamrous, ... Research Square, 2023 | | 2023 |