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Megan E. Yates, MD, PhD
Megan E. Yates, MD, PhD
Verified email at pitt.edu
Title
Cited by
Cited by
Year
Hotspot ESR1 Mutations Are Multimodal and Contextual Modulators of Breast Cancer Metastasis
Z Li, Y Wu, ME Yates, N Tasdemir, A Bahreini, J Chen, KM Levine, ...
Cancer research 82 (7), 1321-1339, 2022
362022
A porcine model of phenylketonuria generated by CRISPR/Cas9 genome editing
EA Koppes, BK Redel, MA Johnson, KJ Skvorak, L Ghaloul-Gonzalez, ...
Jci Insight 5 (20), 2020
352020
Interactions between intersubunit transmembrane domains regulate the chaperone-dependent degradation of an oligomeric membrane protein
TM Buck, AS Jordahl, ME Yates, GM Preston, E Cook, TR Kleyman, ...
Biochemical Journal 474 (3), 357-376, 2017
312017
Synthesis and evaluation of esterified Hsp70 agonists in cellular models of protein aggregation and folding
AN Chiang, M Liang, A Dominguez-Meijide, C Masaracchia, ...
Bioorganic & medicinal chemistry 27 (1), 79-91, 2019
212019
Functional roles of clusters of hydrophobic and polar residues in the epithelial Na+ channel knuckle domain
J Chen, EC Ray, ME Yates, TM Buck, JL Brodsky, CL Kinlough, ...
Journal of Biological Chemistry 290 (41), 25140-25150, 2015
162015
Unique integrated stress response sensors regulate cancer cell susceptibility when Hsp70 activity is compromised
S Sannino, ME Yates, ME Schurdak, S Oesterreich, AV Lee, P Wipf, ...
Elife 10, e64977, 2021
152021
Fusion‐associated carcinomas of the breast: Diagnostic, prognostic, and therapeutic significance
SK Loo, ME Yates, S Yang, S Oesterreich, AV Lee, XS Wang
Genes, Chromosomes and Cancer 61 (5), 261-273, 2022
142022
Surgical management of proximal interphalangeal joint fracture-dislocations: a review of outcomes
C Demino, M Yates, JR Fowler
Hand 16 (4), 453-460, 2021
142021
Loss of E-cadherin induces IGF1R activation and reveals a targetable pathway in invasive lobular breast carcinoma
A Elangovan, J Hooda, L Savariau, S Puthanmadhomnarayanan, ...
Molecular Cancer Research 20 (9), 1405-1419, 2022
102022
Thumb domains of the three epithelial Na+ channel subunits have distinct functions
S Sheng, J Chen, A Mukherjee, ME Yates, TM Buck, JL Brodsky, ...
Journal of Biological Chemistry 293 (45), 17582-17592, 2018
102018
The capture of a disabled proteasome identifies erg25 as a substrate for endoplasmic reticulum associated degradation
TM Buck, X Zeng, PS Cantrell, RT Cattley, Z Hasanbasri, ME Yates, ...
Molecular & Cellular Proteomics 19 (11), 1896-1909, 2020
72020
Hotspot ESR1 mutations are multimodal and contextual drivers of breast cancer metastasis
Z Li, Y Wu, ME Yates, N Tasdemir, A Bahreini, J Chen, KM Levine, ...
BioRxiv, 2021.02. 10.430701, 2021
42021
The EstroGene database reveals diverse temporal, context-dependent, and bidirectional estrogen receptor regulomes in breast cancer
Z Li, T Li, ME Yates, Y Wu, A Ferber, L Chen, DD Brown, JS Carroll, ...
Cancer Research 83 (16), 2656-2674, 2023
32023
Lhs1 dependent ERAD is determined by transmembrane domain context
M Sukhoplyasova, AM Keith, EM Perrault, HE Vorndran, AS Jordahl, ...
Biochemical Journal 480 (18), 1459-1473, 2023
22023
Abstract P3-08-10: Combining multiomics and histological assessment to identify patient derived xenograft models of invasive lobular carcinoma
JM Atkinson, M Yates, DD Brown, J Hooda, R Bhargava, P Schiavini, ...
Cancer Research 83 (5_Supplement), P3-08-10-P3-08-10, 2023
2023
Abstract P6-14-02: Hope for OTHERS–An organ donation program for metastatic breast cancer research
S Oesterreich, L Miller, MQ Rosenzweig, TL Bartholow, M Yates, ...
Cancer Research 83 (5_Supplement), P6-14-02-P6-14-02, 2023
2023
Abstract PD10-02: PD10-02 Novel ER fusion detection method to gain insight in fusion prevalence and endocrine resistant mechanisms
ME Yates, T Liu, J Hooda, S Yang, R Bao, JM Atkinson, AV LEE, ...
Cancer Research 83 (5_Supplement), PD10-02-PD10-02, 2023
2023
ESR1 fusion proteins invoke breast cancer subtype-dependent enrichment of ligand independent pro-oncogenic signatures and phenotypes
ME Yates, Z Li, Y Li, H Guzolik, X Wang, T Liu, J Hooda, JM Atkinson, ...
bioRxiv, 2023.09. 18.558175, 2023
2023
Functional characterization and clinical prevalence of ESR1 fusions in advanced endocrine resistant breast cancer
ME Yates, T Liu, J Hooda, JM Atkinson, AV Lee, S Oesterreich
Cancer Research 82 (12_Supplement), 881-881, 2022
2022
Loss of E-cadherin induces IGF1R activation revealing a targetable pathway in invasive lobular breast carcinoma
A Elangovan, J Hooda, L Savariau, S Puthanmadhomnarayanan, ...
bioRxiv, 2022.02. 22.480917, 2022
2022
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