Hotspot ESR1 Mutations Are Multimodal and Contextual Modulators of Breast Cancer Metastasis Z Li, Y Wu, ME Yates, N Tasdemir, A Bahreini, J Chen, KM Levine, ... Cancer research 82 (7), 1321-1339, 2022 | 36 | 2022 |
A porcine model of phenylketonuria generated by CRISPR/Cas9 genome editing EA Koppes, BK Redel, MA Johnson, KJ Skvorak, L Ghaloul-Gonzalez, ... Jci Insight 5 (20), 2020 | 35 | 2020 |
Interactions between intersubunit transmembrane domains regulate the chaperone-dependent degradation of an oligomeric membrane protein TM Buck, AS Jordahl, ME Yates, GM Preston, E Cook, TR Kleyman, ... Biochemical Journal 474 (3), 357-376, 2017 | 31 | 2017 |
Synthesis and evaluation of esterified Hsp70 agonists in cellular models of protein aggregation and folding AN Chiang, M Liang, A Dominguez-Meijide, C Masaracchia, ... Bioorganic & medicinal chemistry 27 (1), 79-91, 2019 | 21 | 2019 |
Functional roles of clusters of hydrophobic and polar residues in the epithelial Na+ channel knuckle domain J Chen, EC Ray, ME Yates, TM Buck, JL Brodsky, CL Kinlough, ... Journal of Biological Chemistry 290 (41), 25140-25150, 2015 | 16 | 2015 |
Unique integrated stress response sensors regulate cancer cell susceptibility when Hsp70 activity is compromised S Sannino, ME Yates, ME Schurdak, S Oesterreich, AV Lee, P Wipf, ... Elife 10, e64977, 2021 | 15 | 2021 |
Fusion‐associated carcinomas of the breast: Diagnostic, prognostic, and therapeutic significance SK Loo, ME Yates, S Yang, S Oesterreich, AV Lee, XS Wang Genes, Chromosomes and Cancer 61 (5), 261-273, 2022 | 14 | 2022 |
Surgical management of proximal interphalangeal joint fracture-dislocations: a review of outcomes C Demino, M Yates, JR Fowler Hand 16 (4), 453-460, 2021 | 14 | 2021 |
Loss of E-cadherin induces IGF1R activation and reveals a targetable pathway in invasive lobular breast carcinoma A Elangovan, J Hooda, L Savariau, S Puthanmadhomnarayanan, ... Molecular Cancer Research 20 (9), 1405-1419, 2022 | 10 | 2022 |
Thumb domains of the three epithelial Na+ channel subunits have distinct functions S Sheng, J Chen, A Mukherjee, ME Yates, TM Buck, JL Brodsky, ... Journal of Biological Chemistry 293 (45), 17582-17592, 2018 | 10 | 2018 |
The capture of a disabled proteasome identifies erg25 as a substrate for endoplasmic reticulum associated degradation TM Buck, X Zeng, PS Cantrell, RT Cattley, Z Hasanbasri, ME Yates, ... Molecular & Cellular Proteomics 19 (11), 1896-1909, 2020 | 7 | 2020 |
Hotspot ESR1 mutations are multimodal and contextual drivers of breast cancer metastasis Z Li, Y Wu, ME Yates, N Tasdemir, A Bahreini, J Chen, KM Levine, ... BioRxiv, 2021.02. 10.430701, 2021 | 4 | 2021 |
The EstroGene database reveals diverse temporal, context-dependent, and bidirectional estrogen receptor regulomes in breast cancer Z Li, T Li, ME Yates, Y Wu, A Ferber, L Chen, DD Brown, JS Carroll, ... Cancer Research 83 (16), 2656-2674, 2023 | 3 | 2023 |
Lhs1 dependent ERAD is determined by transmembrane domain context M Sukhoplyasova, AM Keith, EM Perrault, HE Vorndran, AS Jordahl, ... Biochemical Journal 480 (18), 1459-1473, 2023 | 2 | 2023 |
Abstract P3-08-10: Combining multiomics and histological assessment to identify patient derived xenograft models of invasive lobular carcinoma JM Atkinson, M Yates, DD Brown, J Hooda, R Bhargava, P Schiavini, ... Cancer Research 83 (5_Supplement), P3-08-10-P3-08-10, 2023 | | 2023 |
Abstract P6-14-02: Hope for OTHERS–An organ donation program for metastatic breast cancer research S Oesterreich, L Miller, MQ Rosenzweig, TL Bartholow, M Yates, ... Cancer Research 83 (5_Supplement), P6-14-02-P6-14-02, 2023 | | 2023 |
Abstract PD10-02: PD10-02 Novel ER fusion detection method to gain insight in fusion prevalence and endocrine resistant mechanisms ME Yates, T Liu, J Hooda, S Yang, R Bao, JM Atkinson, AV LEE, ... Cancer Research 83 (5_Supplement), PD10-02-PD10-02, 2023 | | 2023 |
ESR1 fusion proteins invoke breast cancer subtype-dependent enrichment of ligand independent pro-oncogenic signatures and phenotypes ME Yates, Z Li, Y Li, H Guzolik, X Wang, T Liu, J Hooda, JM Atkinson, ... bioRxiv, 2023.09. 18.558175, 2023 | | 2023 |
Functional characterization and clinical prevalence of ESR1 fusions in advanced endocrine resistant breast cancer ME Yates, T Liu, J Hooda, JM Atkinson, AV Lee, S Oesterreich Cancer Research 82 (12_Supplement), 881-881, 2022 | | 2022 |
Loss of E-cadherin induces IGF1R activation revealing a targetable pathway in invasive lobular breast carcinoma A Elangovan, J Hooda, L Savariau, S Puthanmadhomnarayanan, ... bioRxiv, 2022.02. 22.480917, 2022 | | 2022 |