| Succinic semialdehyde dehydrogenase deficiency, a disorder of GABA metabolism: an update on pharmacological and enzyme-replacement therapeutic strategies KR Vogel, GR Ainslie, DC Walters, A McConnell, SC Dhamne, ... Journal of inherited metabolic disease 41, 699-708, 2018 | 44 | 2018 |
| Age‐related phenotype and biomarker changes in SSADH deficiency ML DiBacco, JB Roullet, K Kapur, MN Brown, DC Walters, KM Gibson, ... Annals of Clinical and Translational Neurology 6 (1), 114-120, 2019 | 34 | 2019 |
| Post-mortem tissue analyses in a patient with succinic semialdehyde dehydrogenase deficiency (SSADHD). I. Metabolomic outcomes T Kirby, DC Walters, M Brown, E Jansen, GS Salomons, C Turgeon, ... Metabolic brain disease 35, 601-614, 2020 | 23 | 2020 |
| Preclinical tissue distribution and metabolic correlations of vigabatrin, an antiepileptic drug associated with potential use‐limiting visual field defects DC Walters, EEW Jansen, GR Ainslie, GS Salomons, MN Brown, ... Pharmacology Research & Perspectives 7 (1), e00456, 2019 | 17 | 2019 |
| Metabolomic analyses of vigabatrin (VGB)-treated mice: GABA-transaminase inhibition significantly alters amino acid profiles in murine neural and non-neural tissues DC Walters, E Arning, T Bottiglieri, EEW Jansen, GS Salomons, ... Neurochemistry international 125, 151-162, 2019 | 15 | 2019 |
| Vigabatrin-induced retinal functional alterations and second-order neuron plasticity in C57BL/6J mice K Chan, M Hoon, BR Pattnaik, JN Ver Hoeve, B Wahlgren, S Gloe, ... Investigative Ophthalmology & Visual Science 61 (2), 17-17, 2020 | 13 | 2020 |
| Functional analysis of thirty-four suspected pathogenic missense variants in ALDH5A1 gene associated with succinic semialdehyde dehydrogenase deficiency A Pop, DEC Smith, T Kirby, D Walters, KM Gibson, S Mahmoudi, ... Molecular genetics and metabolism 130 (3), 172-178, 2020 | 11 | 2020 |
| Postmortem analyses in a patient with succinic semialdehyde dehydrogenase deficiency (SSADHD): II. Histological, lipid, and gene expression outcomes in regional brain tissue DC Walters, R Lawrence, T Kirby, JT Ahrendsen, MP Anderson, ... Journal of child neurology 36 (13-14), 1177-1188, 2021 | 8 | 2021 |
| Maternal glutamine supplementation in murine succinic semialdehyde dehydrogenase deficiency, a disorder of γ‐aminobutyric acid metabolism MN Brown, DC Walters, MA Schmidt, J Hill, A McConnell, EEW Jansen, ... Journal of inherited metabolic disease 42 (5), 1030-1039, 2019 | 8 | 2019 |
| Cellular and molecular outcomes of glutamine supplementation in the brain of succinic semialdehyde dehydrogenase‐deficient mice MN Brown, KM Gibson, MA Schmidt, DC Walters, E Arning, T Bottiglieri, ... JIMD reports 56 (1), 58-69, 2020 | 7 | 2020 |
| Novel biomarkers and age-related metabolite correlations in plasma and dried blood spots from patients with succinic semialdehyde dehydrogenase deficiency T Kirby, DC Walters, X Shi, C Turgeon, P Rinaldo, E Arning, P Ashcraft, ... Orphanet Journal of Rare Diseases 15, 1-9, 2020 | 5 | 2020 |
| Preferential accumulation of the active S-(+) isomer in murine retina highlights novel mechanisms of vigabatrin-associated retinal toxicity DC Walters, EEW Jansen, GS Salomons, E Arning, P Ashcraft, T Bottiglieri, ... Epilepsy research 170, 106536, 2021 | 4 | 2021 |
| Intestinal dysbiosis as a component of pathophysiology in succinic semialdehyde dehydrogenase deficiency (SSADHD) TO Kirby, X Shi, D Walters, JB Roullet, KM Gibson Molecular Genetics and Metabolism 135 (1), 42-46, 2022 | 3 | 2022 |
| Transcriptome analysis in mice treated with vigabatrin identifies dysregulation of genes associated with retinal signaling circuitry D Walters, KR Vogel, M Brown, X Shi, JB Roullet, KM Gibson Epilepsy research 166, 106395, 2020 | 3 | 2020 |
| Farnesol brain transcriptomics in CNS inflammatory demyelination WJ Doyle, D Walters, X Shi, K Hoffman, K Magori, JB Roullet, ... Clinical Immunology 255, 109752, 2023 | 2 | 2023 |
| Isoprenol-induced neuroprotection in experimental multiple sclerosis J Ochoa-Reparaz, KD Strawn, TO Kirby, MN Brown, DC Walters, ... The Journal of Immunology 200 (1_Supplement), 54.3-54.3, 2018 | 1 | 2018 |
| CHAPTER FIVE: INTESTINAL DYSBIOSIS AS A COMPONENT OF PATHOPHYSIOLOGY IN SUCCINC SEMIALDEHYDE DEHYDROGENASE DEFICIENCY (SSADHD) TO Kirby, X Shi, DC Walters, JB Roullet METABOLOME-MICROBIOME INTERRELATIONSHIPS IN THE PATHOPHYSIOLOGY OF SUCCINIC …, 2022 | | 2022 |
| CHAPTER FOUR: PREFERENTIAL ACCUMULATION OF THE ACTIVE S-(+) ISOMER IN MURINE RETINA HIGHLIGHTS NOVEL MECHANISMS OF VIGABATRIN-ASSOCIATED RETINAL TOXICITY DC Walters, EEW Jansen, GS Salomons, E Arning, P Ashcraft, T Bottiglieri, ... OCULAR AND SYSTEMIC METABOLOMIC/GENOMIC DYSREGULATION IN THE VIGABATRIN …, 2022 | | 2022 |
| CHAPTER SEVEN: POST-MORTEM ANALYSES IN A PATIENT WITH SUCCINIC SEMIALDEHYDE DEHYDROGENASE DEFICIENCY (SSADHD): II. HISTOLOGICAL, LIPID, AND GENE EXPRESSION OUTCOMES IN REGIONAL … DC Walters, R Lawrence, T Kirby, JT Ahrendsen, MP Anderson, ... OCULAR AND SYSTEMIC METABOLOMIC/GENOMIC DYSREGULATION IN THE VIGABATRIN …, 2022 | | 2022 |
| CHAPTER THREE: METABOLOMIC ANALYSES OF VIGABATRIN (VGB)-TREATED MICE: GABA-TRANSAMINASE INHIBITION SIGNIFICANTLY ALTERS AMINO ACID PROFILES IN NEURAL AND NON-NEURAL TISSUES E Contributors, DC Walters, E Arning, T Bottiglieri OCULAR AND SYSTEMIC METABOLOMIC/GENOMIC DYSREGULATION IN THE VIGABATRIN …, 2022 | | 2022 |
