Clinical aspects of transporter‐mediated drug–drug interactions A Gessner, J König, MF Fromm Clinical Pharmacology & Therapeutics 105 (6), 1386-1394, 2019 | 119 | 2019 |
A cryptic polyene biosynthetic gene cluster in Streptomyces calvus is expressed upon complementation with a functional bldA gene L Kalan, A Gessner, MN Thaker, N Waglechner, XM Zhu, A Szawiola, ... Chemistry & biology 20 (10), 1214-1224, 2013 | 83 | 2013 |
Complete genome sequence of Saccharothrix espanaensis DSM 44229T and comparison to the other completely sequenced Pseudonocardiaceae T Strobel, A Al-Dilaimi, J Blom, A Gessner, J Kalinowski, M Luzhetska, ... BMC genomics 13, 1-13, 2012 | 53 | 2012 |
Trimethylamine-N-oxide (TMAO) determined by LC-MS/MS: distribution and correlates in the population-based PopGen cohort A Gessner, R di Giuseppe, M Koch, MF Fromm, W Lieb, R Maas Clinical Chemistry and Laboratory Medicine (CCLM) 58 (5), 733-740, 2020 | 41 | 2020 |
Contribution of multidrug and toxin extrusion protein 1 (MATE1) to renal secretion of trimethylamine-N-oxide (TMAO) A Gessner, J König, MF Fromm Scientific Reports 8 (1), 6659, 2018 | 27 | 2018 |
Changing Biosynthetic Profiles by Expressing bldA in Streptomyces Strains A Gessner, T Heitzler, S Zhang, C Klaus, R Murillo, H Zhao, S Vanner, ... ChemBioChem 16 (15), 2244-2252, 2015 | 23 | 2015 |
L-arginine metabolism inhibits arthritis and inflammatory bone loss S Cao, Y Li, R Song, X Meng, M Fuchs, C Liang, K Kachler, X Meng, ... Annals of the rheumatic diseases 83 (1), 72-87, 2024 | 21 | 2024 |
An easily expandable multi-drug LC-MS assay for the simultaneous quantification of 57 oral antitumor drugs in human plasma N Kehl, K Schlichtig, P Dürr, L Bellut, F Dörje, R Fietkau, M Pavel, ... Cancers 13 (24), 6329, 2021 | 12 | 2021 |
N1‐Methylnicotinamide as Biomarker for MATE‐Mediated Renal Drug–Drug Interactions: Impact of Cimetidine, Rifampin, Verapamil, and Probenecid F Müller, K Hohl, S Keller, S Schmidt‐Gerets, B Deutsch, A Schuler‐Metz, ... Clinical Pharmacology & Therapeutics 113 (5), 1070-1079, 2023 | 10 | 2023 |
A Metabolomic Analysis of Sensitivity and Specificity of 23 Previously Proposed Biomarkers for Renal Transporter‐Mediated Drug‐Drug Interactions A Gessner, F Müller, P Wenisch, MR Heinrich, J König, P Stopfer, ... Clinical Pharmacology & Therapeutics 114 (5), 1058-1072, 2023 | 9 | 2023 |
Cancer-Type Organic Anion Transporting Polypeptide 1B3 Is Localized in Lysosomes and Mediates Resistance against Kinase Inhibitors B Haberkorn, S Oswald, N Kehl, A Gessner, RV Taudte, JP Dobert, ... Molecular Pharmacology 102 (6), 248-258, 2022 | 8 | 2022 |
Establishment of reference values for the lysine acetylation marker Nɛ-acetyllysine in small volume human plasma samples by a multi-target LC–MS/MS method A Gessner, M Mieth, D Auge, A Chafai, F Müller, MF Fromm, R Maas Amino acids 51, 1259-1271, 2019 | 8 | 2019 |
Effects of treatment with SGLT-2 inhibitors on arginine-related cardiovascular and renal biomarkers A Gessner, A Gemeinhardt, A Bosch, D Kannenkeril, C Staerk, A Mayr, ... Cardiovascular Diabetology 21 (1), 4, 2022 | 6 | 2022 |
Vectorial transport of the arginine derivatives asymmetric dimethylarginine (ADMA) and l-homoarginine by OATP4C1 and P-glycoprotein studied in double-transfected MDCK cells E Taghikhani, R Maas, RV Taudte, A Gessner, MF Fromm, J König Amino Acids 52 (6), 975-985, 2020 | 6 | 2020 |
GLUT1-mediated glucose import in B cells is critical for anaplerotic balance and humoral immunity TEH Bierling, A Gumann, SR Ottmann, SR Schulz, L Weckwerth, ... Cell Reports 43 (2), 2024 | 4 | 2024 |
Acod1-mediated inhibition of aerobic glycolysis suppresses osteoclast differentiation and attenuates bone erosion in arthritis K Kachler, D Andreev, S Thapa, D Royzman, A Gießl, S Karuppusamy, ... Annals of the Rheumatic Diseases 83 (12), 1691-1706, 2024 | 2 | 2024 |
ATP citrate lyase (ACLY)-dependent immunometabolism in mucosal T cells drives experimental colitis in vivo A Schulz-Kuhnt, K Rühle, A Javidmehr, M Döbrönti, J Biwank, S Knittel, ... Gut 73 (4), 601-612, 2024 | 2 | 2024 |
A supervised machine-learning approach for the efficient development of a multi method (LC-MS) for a large number of drugs and subsets thereof: focus on oral antitumor agents N Kehl, A Gessner, R Maas, MF Fromm, RV Taudte Clinical Chemistry and Laboratory Medicine (CCLM) 62 (2), 293-302, 2024 | 2 | 2024 |
An easily expandable multi-drug LC-MS assay for the simultaneous quantification of 57 oral antitumor drugs in human plasma. Cancers 2021; 13: 6329 N Kehl, K Schlichtig, P Dürr, L Bellut, F Dörje, R Fietkau, M Pavel, ... s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021 | 1 | 2021 |
Association of plasma concentration of trimethylamine N-oxide and ADP-induced platelet reactivity after a loading dose of clopidogrel 600 mg in patients undergoing elective PCI C Stratz, A Gessner, MF Fromm, J Hromek, T Nuehrenberg, L Hille, ... EUROPEAN HEART JOURNAL 39, 678-678, 2018 | 1 | 2018 |