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Lena M. Kutscher
Lena M. Kutscher
DKFZ Junior Group Leader, German Cancer Research Center
Verified email at kitz-heidelberg.de - Homepage
Title
Cited by
Cited by
Year
Forward and reverse mutagenesis in C. elegans
LM Kutscher, S Shaham
WormBook: the online review of C. elegans biology, 1, 2014
1422014
Long-term high-resolution imaging of developing C. elegans larvae with microfluidics
W Keil, LM Kutscher, S Shaham, ED Siggia
Developmental cell 40 (2), 202-214, 2017
902017
Non-apoptotic cell death in animal development
LM Kutscher, S Shaham
Cell Death & Differentiation 24 (8), 1326-1336, 2017
662017
Developmental and evolutionary dynamics of cis-regulatory elements in mouse cerebellar cells
I Sarropoulos, M Sepp, R Frömel, K Leiss, N Trost, E Leushkin, ...
Science 373 (6558), eabg4696, 2021
522021
TBC-8, a Putative RAB-2 GAP, Regulates Dense Core Vesicle Maturation in Caenorhabditis elegans
M Hannemann, N Sasidharan, J Hegermann, LM Kutscher, S Koenig, ...
PLoS genetics 8 (5), e1002722, 2012
312012
Cellular development and evolution of the mammalian cerebellum
M Sepp, K Leiss, F Murat, K Okonechnikov, P Joshi, E Leushkin, L Spänig, ...
Nature 625 (7996), 788-796, 2024
222024
Functional loss of a noncanonical BCOR–PRC1. 1 complex accelerates SHH-driven medulloblastoma formation
LM Kutscher, K Okonechnikov, NV Batora, J Clark, PBG Silva, M Vouri, ...
Genes & development 34 (17-18), 1161-1176, 2020
192020
RAB-35 and ARF-6 GTPases mediate engulfment and clearance following linker cell-type death
LM Kutscher, W Keil, S Shaham
Developmental cell 47 (2), 222-238. e6, 2018
162018
Mapping pediatric brain tumors to their origins in the developing cerebellum
K Okonechnikov, P Joshi, M Sepp, K Leiss, I Sarropoulos, F Murat, M Sill, ...
Neuro-oncology 25 (10), 1895-1909, 2023
92023
The regulatory landscape of cells in the developing mouse cerebellum
I Sarropoulos, M Sepp, R Frömel, K Leiss, N Trost, E Leushkin, ...
BioRxiv, 2021.01. 29.428632, 2021
42021
Modeling brain and neural crest neoplasms with human pluripotent stem cells
C Schloo, LM Kutscher
Neuro-oncology 25 (7), 1225-1235, 2023
32023
MEDB-22. iPSC-derived cerebellar organoid model for hereditary genetic predisposition in SHH-medulloblastoma
F Manz, D Haag, SM Pfister, L Kutscher
Neuro-Oncology 24 (Suppl 1), i109, 2022
12022
Probing medulloblastoma initiation at the single-cell level
K Okonechnikov, SM Pfister, LM Kutscher
Trends in Cancer 5 (12), 759-761, 2019
12019
The Virtual Child
RJ Gilbertson, S Behjati, AL Böttcher, ME Bronner, M Burridge, ...
Cancer Discovery 14 (4), 663-668, 2024
2024
Loss of the Familial Dysautonomia gene Elp1 in cerebellar granule cell progenitors leads to ataxia in mice
F Manz, PBG da Silva, ME Schouw, C Lukasch, L Bianchini, L Sieber, ...
bioRxiv, 2024.03. 27.586801, 2024
2024
Medulloblastoma oncogene aberrations are not involved in tumor initiation, but essential for disease progression and therapy resistance
K Okonechnikov, P Joshi, V Koerber, A Rademacher, M Bortolomeazzi, ...
bioRxiv, 2024.02. 09.579690, 2024
2024
Gene regulatory network landscape of Group 3/4 medulloblastoma
P Joshi, T Stelzer, K Okonechnikov, I Sarropoulos, M Sepp, ...
bioRxiv, 2024.02. 09.579680, 2024
2024
HGG-07. OVEREXPRESSION OF A PLAG-FAMILY TRANSCRIPTION FACTOR DURING MURINE BRAIN DEVELOPMENT CAUSES BRAIN TUMOR FORMATION
J Vaillant, A Wittmann, MK Keck, JS Rozowsky, MG Filbin, SM Pfister, ...
Neuro-Oncology 25 (Suppl 1), i39, 2023
2023
MDB-23. ELP1 GERMLINE DEFICIENCY SENSITIZES THE GRANULE NEURON LINEAGE TO SHH MEDULLOBLASTOMA AND EXPOSES NOVEL THERAPEUTIC VULNERABILITIES
J Garcia-Lopez, ST Ahmad, Y Li, B Gudenas, M Kojic, F Manz, B Jonchere, ...
Neuro-Oncology 25 (Supplement_1), i67-i67, 2023
2023
EVALUATION OF CAR-T CELLS TARGETING CD276 IN MEDULLOBLASTOMA
PBG da Silva, L Sieber, N Mack, D Atar, LM Kutscher, P Schlegel, ...
NEURO-ONCOLOGY 24, 83-83, 2022
2022
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