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Dereje Abate Negatu, PhD
Dereje Abate Negatu, PhD
Center for Discovery and Innovation, Hackensack Meridian Health
Verified email at hmh-cdi.org
Title
Cited by
Cited by
Year
Gut Microbiota Metabolite Indole Propionic Acid Targets Tryptophan Biosynthesis in Mycobacterium tuberculosis
DA Negatu, Y Yamada, Y Xi, ML Go, M Zimmerman, U Ganapathy, ...
MBio 10 (2), 10.1128/mbio. 02781-18, 2019
712019
Whole-cell screen of fragment library identifies gut microbiota metabolite indole propionic acid as antitubercular
DA Negatu, JJJ Liu, M Zimmerman, F Kaya, V Dartois, CC Aldrich, ...
Antimicrobial agents and chemotherapy 62 (3), 10.1128/aac. 01571-17, 2018
712018
Indole propionic acid, an unusual antibiotic produced by the gut microbiota, with anti-inflammatory and antioxidant properties
DA Negatu, M Gengenbacher, V Dartois, T Dick
Frontiers in Microbiology 11, 575586, 2020
662020
Epidemiology of anti-tuberculosis drug resistance patterns and trends in tuberculosis referral hospital in Addis Ababa, Ethiopia
D Abate, B Taye, M Abseno, S Biadgilign
BMC research notes 5, 1-6, 2012
632012
Isoniazid and rifampicin resistance mutations and their effect on second-line anti-tuberculosis treatment
D Abate, Y Tedla, D Meressa, G Ameni
The International Journal of tuberculosis and lung disease 18 (8), 946-951, 2014
532014
Piperidine-4-carboxamides target DNA gyrase in Mycobacterium abscessus
DA Negatu, A Beuchel, A Madani, N Alvarez, C Chen, WW Aragaw, ...
Antimicrobial agents and chemotherapy 65 (8), 10.1128/aac. 00676-21, 2021
162021
Strongly bactericidal all-oral β-lactam combinations for the treatment of Mycobacterium abscessus lung disease
DA Negatu, MD Zimmerman, V Dartois, T Dick
Antimicrobial Agents and Chemotherapy 66 (9), e00790-22, 2022
142022
Functionalized Dioxonaphthoimidazoliums: A Redox Cycling Chemotype with Potent Bactericidal Activities against Mycobacterium tuberculosis
KT Fridianto, M Li, K Hards, DA Negatu, GM Cook, T Dick, Y Lam, ML Go
Journal of medicinal chemistry 64 (21), 15991-16007, 2021
132021
Gut microbiota metabolite indole propionic acid targets tryptophan biosynthesis in Mycobacterium tuberculosis. mBio. 2019; 10 (2): e02781-18
DA Negatu, Y Yamada, Y Xi, ML Go, M Zimmerman, U Ganapathy, ...
DOI 10, 02781-18, 0
10
Gut microbiota metabolite indole propionic acid targets tryptophan biosynthesis in Mycobacterium tuberculosis. mBio 10: e02781-18
DA Negatu, Y Yamada, Y Xi, ML Go, M Zimmerman, U Ganapathy, ...
82019
Activity of oral tebipenem-avibactam in a mouse model of Mycobacterium abscessus lung infection
DA Negatu, R González del Río, M Cacho-Izquierdo, D Barros-Aguirre, ...
Antimicrobial Agents and Chemotherapy 67 (2), e01459-22, 2023
72023
Structure–Activity Relationship of Anti-Mycobacterium abscessus Piperidine-4-carboxamides, a New Class of NBTI DNA Gyrase Inhibitors
A Beuchel, D Robaa, DA Negatu, A Madani, N Alvarez, MD Zimmerman, ...
ACS Medicinal Chemistry Letters 13 (3), 417-427, 2022
72022
Side-by-side profiling of oxazolidinones to estimate the therapeutic window against mycobacterial infections
DA Negatu, WW Aragaw, J Cangialosi, V Dartois, T Dick
Antimicrobial Agents and Chemotherapy 67 (4), e01655-22, 2023
62023
Activity of tricyclic pyrrolopyrimidine gyrase B inhibitor against Mycobacterium abscessus
A Madani, DA Negatu, A El Marrouni, RR Miller, CW Boyce, N Murgolo, ...
Antimicrobial Agents and Chemotherapy 66 (9), e00669-22, 2022
62022
Pharmacological validation of dihydrofolate reductase as a drug target in Mycobacterium abscessus
WW Aragaw, DA Negatu, CJ Bungard, VA Dartois, AE Marrouni, ...
Antimicrobial Agents and Chemotherapy 68 (1), e00717-23, 2024
12024
Oral β-lactam pairs for the treatment of Mycobacterium avium complex pulmonary disease
DA Negatu, SJ Shin, SY Kim, BW Jhun, V Dartois, T Dick
The Journal of Infectious Diseases, jiad591, 2023
12023
Characterization of In Vitro Resistance to Linezolid in Mycobacterium abscessus
DA Negatu, WW Aragaw, V Dartois, T Dick
Microbiology Spectrum 11 (4), e02199-23, 2023
12023
A pairwise approach to revitalize β-lactams for the treatment of TB
DA Negatu, WW Aragaw, V Dartois, T Dick
Antimicrobial Agents and Chemotherapy, e00034-24, 2024
2024
FRAGMENT LIBRARY SCREEN IDENTIFIES MICROBIOTA METABOLITE THAT TARGETS TRYPTOPHAN BIOSYNTHESIS IN MYCOBACTERIUM TUBERCULOSIS
DA NEGATU
2019
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Articles 1–19