Gut Microbiota Metabolite Indole Propionic Acid Targets Tryptophan Biosynthesis in Mycobacterium tuberculosis DA Negatu, Y Yamada, Y Xi, ML Go, M Zimmerman, U Ganapathy, ... MBio 10 (2), 10.1128/mbio. 02781-18, 2019 | 71 | 2019 |
Whole-cell screen of fragment library identifies gut microbiota metabolite indole propionic acid as antitubercular DA Negatu, JJJ Liu, M Zimmerman, F Kaya, V Dartois, CC Aldrich, ... Antimicrobial agents and chemotherapy 62 (3), 10.1128/aac. 01571-17, 2018 | 71 | 2018 |
Indole propionic acid, an unusual antibiotic produced by the gut microbiota, with anti-inflammatory and antioxidant properties DA Negatu, M Gengenbacher, V Dartois, T Dick Frontiers in Microbiology 11, 575586, 2020 | 66 | 2020 |
Epidemiology of anti-tuberculosis drug resistance patterns and trends in tuberculosis referral hospital in Addis Ababa, Ethiopia D Abate, B Taye, M Abseno, S Biadgilign BMC research notes 5, 1-6, 2012 | 63 | 2012 |
Isoniazid and rifampicin resistance mutations and their effect on second-line anti-tuberculosis treatment D Abate, Y Tedla, D Meressa, G Ameni The International Journal of tuberculosis and lung disease 18 (8), 946-951, 2014 | 53 | 2014 |
Piperidine-4-carboxamides target DNA gyrase in Mycobacterium abscessus DA Negatu, A Beuchel, A Madani, N Alvarez, C Chen, WW Aragaw, ... Antimicrobial agents and chemotherapy 65 (8), 10.1128/aac. 00676-21, 2021 | 16 | 2021 |
Strongly bactericidal all-oral β-lactam combinations for the treatment of Mycobacterium abscessus lung disease DA Negatu, MD Zimmerman, V Dartois, T Dick Antimicrobial Agents and Chemotherapy 66 (9), e00790-22, 2022 | 14 | 2022 |
Functionalized Dioxonaphthoimidazoliums: A Redox Cycling Chemotype with Potent Bactericidal Activities against Mycobacterium tuberculosis KT Fridianto, M Li, K Hards, DA Negatu, GM Cook, T Dick, Y Lam, ML Go Journal of medicinal chemistry 64 (21), 15991-16007, 2021 | 13 | 2021 |
Gut microbiota metabolite indole propionic acid targets tryptophan biosynthesis in Mycobacterium tuberculosis. mBio. 2019; 10 (2): e02781-18 DA Negatu, Y Yamada, Y Xi, ML Go, M Zimmerman, U Ganapathy, ... DOI 10, 02781-18, 0 | 10 | |
Gut microbiota metabolite indole propionic acid targets tryptophan biosynthesis in Mycobacterium tuberculosis. mBio 10: e02781-18 DA Negatu, Y Yamada, Y Xi, ML Go, M Zimmerman, U Ganapathy, ... | 8 | 2019 |
Activity of oral tebipenem-avibactam in a mouse model of Mycobacterium abscessus lung infection DA Negatu, R González del Río, M Cacho-Izquierdo, D Barros-Aguirre, ... Antimicrobial Agents and Chemotherapy 67 (2), e01459-22, 2023 | 7 | 2023 |
Structure–Activity Relationship of Anti-Mycobacterium abscessus Piperidine-4-carboxamides, a New Class of NBTI DNA Gyrase Inhibitors A Beuchel, D Robaa, DA Negatu, A Madani, N Alvarez, MD Zimmerman, ... ACS Medicinal Chemistry Letters 13 (3), 417-427, 2022 | 7 | 2022 |
Side-by-side profiling of oxazolidinones to estimate the therapeutic window against mycobacterial infections DA Negatu, WW Aragaw, J Cangialosi, V Dartois, T Dick Antimicrobial Agents and Chemotherapy 67 (4), e01655-22, 2023 | 6 | 2023 |
Activity of tricyclic pyrrolopyrimidine gyrase B inhibitor against Mycobacterium abscessus A Madani, DA Negatu, A El Marrouni, RR Miller, CW Boyce, N Murgolo, ... Antimicrobial Agents and Chemotherapy 66 (9), e00669-22, 2022 | 6 | 2022 |
Pharmacological validation of dihydrofolate reductase as a drug target in Mycobacterium abscessus WW Aragaw, DA Negatu, CJ Bungard, VA Dartois, AE Marrouni, ... Antimicrobial Agents and Chemotherapy 68 (1), e00717-23, 2024 | 1 | 2024 |
Oral β-lactam pairs for the treatment of Mycobacterium avium complex pulmonary disease DA Negatu, SJ Shin, SY Kim, BW Jhun, V Dartois, T Dick The Journal of Infectious Diseases, jiad591, 2023 | 1 | 2023 |
Characterization of In Vitro Resistance to Linezolid in Mycobacterium abscessus DA Negatu, WW Aragaw, V Dartois, T Dick Microbiology Spectrum 11 (4), e02199-23, 2023 | 1 | 2023 |
A pairwise approach to revitalize β-lactams for the treatment of TB DA Negatu, WW Aragaw, V Dartois, T Dick Antimicrobial Agents and Chemotherapy, e00034-24, 2024 | | 2024 |
FRAGMENT LIBRARY SCREEN IDENTIFIES MICROBIOTA METABOLITE THAT TARGETS TRYPTOPHAN BIOSYNTHESIS IN MYCOBACTERIUM TUBERCULOSIS DA NEGATU | | 2019 |