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Fan Yang
Fan Yang
Verified email at astrazeneca.com
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Year
NLRX1 negatively modulates type I IFN to facilitate KSHV reactivation from latency
Z Ma, SE Hopcraft, F Yang, A Petrucelli, H Guo, JPY Ting, DP Dittmer, ...
PLoS pathogens 13 (5), e1006350, 2017
412017
A CK1α activator penetrates the brain and shows efficacy against drug-resistant metastatic medulloblastoma
J Rodriguez-Blanco, B Li, J Long, C Shen, F Yang, D Orton, S Collins, ...
Clinical cancer research 25 (4), 1379-1388, 2019
242019
The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling
C Shen, A Nayak, LR Neitzel, AA Adams, M Silver-Isenstadt, LM Sawyer, ...
Nature communications 12 (1), 5263, 2021
232021
Noncanonical activation of GLI signaling in SOX2+ cells drives medulloblastoma relapse
M Swiderska-Syn, J Mir-Pedrol, A Oles, O Schleuger, AD Salvador, ...
Science advances 8 (29), eabj9138, 2022
122022
A Druggable UHRF1/DNMT1/GLI Complex Regulates Sonic Hedgehog–Dependent Tumor Growth
F Yang, J Rodriguez-Blanco, J Long, M Swiderska-Syn, DT Wynn, B Li, ...
Molecular Cancer Research 20 (11), 1598-1610, 2022
52022
The casein kinase 1α agonist pyrvinium attenuates Wnt-mediated CK1α degradation via interaction with the E3 ubiquitin ligase component Cereblon
C Shen, A Nayak, LR Neitzel, F Yang, B Li, CH Williams, CC Hong, ...
Journal of Biological Chemistry 298 (8), 2022
42022
Protein arginine methyltransferase 5 regulates SHH-subgroup medulloblastoma progression
DT Wynn, J Rodriguez-Blanco, J Long, F Yang, C Shen, D Fei, HY Tang, ...
Neuro-Oncology Advances 4 (1), vdac144, 2022
32022
Multiprotein GLI Transcriptional Complexes as Therapeutic Targets in Cancer
F Yang, DT Wynn, C Shen, NG Ayad, DJ Robbins
Life 12 (12), 1967, 2022
2022
THER-28. A CK1α ACTIVATOR PENETRATES THE BRAIN, AND SHOWS EFFICACY AGAINST DRUG-RESISTANT METASTATIC MEDULLOBLASTOMA
J Rodriguez, B Li, J Long, C Shen, F Yang, D Orthon, S Collins, ...
Neuro-oncology 21 (Suppl 2), ii119, 2019
2019
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