NLRX1 negatively modulates type I IFN to facilitate KSHV reactivation from latency Z Ma, SE Hopcraft, F Yang, A Petrucelli, H Guo, JPY Ting, DP Dittmer, ... PLoS pathogens 13 (5), e1006350, 2017 | 41 | 2017 |
A CK1α activator penetrates the brain and shows efficacy against drug-resistant metastatic medulloblastoma J Rodriguez-Blanco, B Li, J Long, C Shen, F Yang, D Orton, S Collins, ... Clinical cancer research 25 (4), 1379-1388, 2019 | 24 | 2019 |
The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling C Shen, A Nayak, LR Neitzel, AA Adams, M Silver-Isenstadt, LM Sawyer, ... Nature communications 12 (1), 5263, 2021 | 23 | 2021 |
Noncanonical activation of GLI signaling in SOX2+ cells drives medulloblastoma relapse M Swiderska-Syn, J Mir-Pedrol, A Oles, O Schleuger, AD Salvador, ... Science advances 8 (29), eabj9138, 2022 | 12 | 2022 |
A Druggable UHRF1/DNMT1/GLI Complex Regulates Sonic Hedgehog–Dependent Tumor Growth F Yang, J Rodriguez-Blanco, J Long, M Swiderska-Syn, DT Wynn, B Li, ... Molecular Cancer Research 20 (11), 1598-1610, 2022 | 5 | 2022 |
The casein kinase 1α agonist pyrvinium attenuates Wnt-mediated CK1α degradation via interaction with the E3 ubiquitin ligase component Cereblon C Shen, A Nayak, LR Neitzel, F Yang, B Li, CH Williams, CC Hong, ... Journal of Biological Chemistry 298 (8), 2022 | 4 | 2022 |
Protein arginine methyltransferase 5 regulates SHH-subgroup medulloblastoma progression DT Wynn, J Rodriguez-Blanco, J Long, F Yang, C Shen, D Fei, HY Tang, ... Neuro-Oncology Advances 4 (1), vdac144, 2022 | 3 | 2022 |
Multiprotein GLI Transcriptional Complexes as Therapeutic Targets in Cancer F Yang, DT Wynn, C Shen, NG Ayad, DJ Robbins Life 12 (12), 1967, 2022 | | 2022 |
THER-28. A CK1α ACTIVATOR PENETRATES THE BRAIN, AND SHOWS EFFICACY AGAINST DRUG-RESISTANT METASTATIC MEDULLOBLASTOMA J Rodriguez, B Li, J Long, C Shen, F Yang, D Orthon, S Collins, ... Neuro-oncology 21 (Suppl 2), ii119, 2019 | | 2019 |