Lactate buildup at the site of chronic inflammation promotes disease by inducing CD4+ T cell metabolic rewiring V Pucino, M Certo, V Bulusu, D Cucchi, K Goldmann, E Pontarini, R Haas, ... Cell metabolism 30 (6), 1055-1074. e8, 2019 | 335 | 2019 |
Molecular portraits of early rheumatoid arthritis identify clinical and treatment response phenotypes MJ Lewis, MR Barnes, K Blighe, K Goldmann, S Rana, JA Hackney, ... Cell reports 28 (9), 2455-2470. e5, 2019 | 283 | 2019 |
Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial F Rivellese, AEA Surace, K Goldmann, E Sciacca, C Çubuk, G Giorli, ... Nature medicine 28 (6), 1256-1268, 2022 | 125 | 2022 |
M3C: Monte Carlo reference-based consensus clustering CR John, D Watson, D Russ, K Goldmann, M Ehrenstein, C Pitzalis, ... Scientific reports 10 (1), 1816, 2020 | 102 | 2020 |
B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure F Rivellese, F Humby, S Bugatti, L Fossati‐Jimack, H Rizvi, D Lucchesi, ... Arthritis & Rheumatology 72 (5), 714-725, 2020 | 43 | 2020 |
Interleukin-36 family dysregulation drives joint inflammation and therapy response in psoriatic arthritis MA Boutet, A Nerviani, G Lliso-Ribera, D Lucchesi, E Prediletto, ... Rheumatology 59 (4), 828-838, 2020 | 42 | 2020 |
Extracellular traps and PAD4 released by macrophages induce citrullination and auto-antibody production in autoimmune arthritis MEM El Shikh, R El Sayed, A Nerviani, K Goldmann, CR John, R Hands, ... Journal of Autoimmunity 105, 102297, 2019 | 42 | 2019 |
Role of synovial fibroblast subsets across synovial pathotypes in rheumatoid arthritis: a deconvolution analysis R Micheroli, M Elhai, S Edalat, M Frank-Bertoncelj, K Bürki, A Ciurea, ... RMD open 8 (1), e001949, 2022 | 39 | 2022 |
IL-23 skin and joint profiling in psoriatic arthritis: novel perspectives in understanding clinical responses to IL-23 inhibitors A Nerviani, MA Boutet, WSG Tan, K Goldmann, N Purkayastha, TA Lajtos, ... Annals of the Rheumatic Diseases 80 (5), 591-597, 2021 | 32 | 2021 |
Interferon-α-mediated therapeutic resistance in early rheumatoid arthritis implicates epigenetic reprogramming FAH Cooles, J Tarn, DW Lendrem, N Naamane, CMA Lin, B Millar, ... Annals of the rheumatic diseases 81 (9), 1214-1223, 2022 | 26 | 2022 |
The RA-MAP Consortium: a working model for academia–industry collaboration AP Cope, MR Barnes, A Belson, M Binks, S Brockbank, ... Nature Reviews Rheumatology 14 (1), 53-60, 2018 | 20 | 2018 |
Effects of targeting the transcription factors Ikaros and Aiolos on B cell activation and differentiation in systemic lupus erythematosus F Rivellese, S Manou-Stathopoulou, D Mauro, K Goldmann, D Pyne, ... Lupus Science & Medicine 8 (1), e000445, 2021 | 19 | 2021 |
Circulating and synovial pentraxin-3 (PTX3) expression levels correlate with rheumatoid arthritis severity and tissue infiltration independently of conventional treatments response MA Boutet, A Nerviani, G Lliso-Ribera, R Leone, M Sironi, R Hands, ... Frontiers in immunology 12, 686795, 2021 | 15 | 2021 |
Investigation of genetically regulated gene expression and response to treatment in rheumatoid arthritis highlights an association between IL18RAP expression and treatment response S Cherlin, MJ Lewis, D Plant, N Nair, K Goldmann, E Tzanis, MR Barnes, ... Annals of the rheumatic diseases 79 (11), 1446-1452, 2020 | 15 | 2020 |
Analysis of complement gene expression, clinical associations, and biodistribution of complement proteins in the synovium of early rheumatoid arthritis patients reveals unique … NK Banda, KD Deane, EA Bemis, C Strickland, J Seifert, K Jordan, ... The Journal of Immunology 208 (11), 2482-2496, 2022 | 12 | 2022 |
nestedcv: an R package for fast implementation of nested cross-validation with embedded feature selection designed for transcriptomics and high-dimensional data MJ Lewis, A Spiliopoulou, K Goldmann, C Pitzalis, P McKeigue, ... Bioinformatics Advances 3 (1), vbad048, 2023 | 10 | 2023 |
UBE2L3 regulates TLR7-induced B cell autoreactivity in Systemic Lupus Erythematosus D Mauro, S Manou-Stathopoulou, F Rivellese, E Sciacca, K Goldmann, ... Journal of Autoimmunity 136, 103023, 2023 | 9 | 2023 |
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients Scientific data 9 (1), 196, 2022 | 8 | 2022 |
M3C: A Monte Carlo reference-based consensus clustering algorithm CR John, D Watson, M Lewis, D Russ, K Goldmann, M Ehrenstein, ... bioRxiv, 377002, 2018 | 8 | 2018 |
Network analysis of synovial RNA sequencing identifies gene-gene interactions predictive of response in rheumatoid arthritis E Sciacca, AEA Surace, S Alaimo, A Pulvirenti, F Rivellese, K Goldmann, ... Arthritis Research & Therapy 24 (1), 166, 2022 | 6 | 2022 |