| Myostatin induces cachexia by activating the ubiquitin proteolytic system through an NF‐κB‐independent, FoxO1‐dependent mechanism C McFarlane, E Plummer, M Thomas, A Hennebry, M Ashby, N Ling, ... Journal of cellular physiology 209 (2), 501-514, 2006 | 602 | 2006 |
| Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy MM Reza, N Subramaniyam, CM Sim, X Ge, D Sathiakumar, C McFarlane, ... Nature communications 8 (1), 1104, 2017 | 247 | 2017 |
| Myostatin signals through Pax7 to regulate satellite cell self-renewal C McFarlane, A Hennebry, M Thomas, E Plummer, N Ling, M Sharma, ... Experimental cell research 314 (2), 317-329, 2008 | 214 | 2008 |
| Inhibition of myostatin protects against diet-induced obesity by enhancing fatty acid oxidation and promoting a brown adipose phenotype in mice C Zhang, C McFarlane, S Lokireddy, S Masuda, X Ge, PD Gluckman, ... Diabetologia 55, 183-193, 2012 | 206 | 2012 |
| Modulation of reactive oxygen species in skeletal muscle by myostatin is mediated through NF‐κB S Sriram, S Subramanian, D Sathiakumar, R Venkatesh, MS Salerno, ... Aging cell 10 (6), 931-948, 2011 | 201 | 2011 |
| Mitochondrial oxidative capacity and NAD+ biosynthesis are reduced in human sarcopenia across ethnicities E Migliavacca, SKH Tay, HP Patel, T Sonntag, G Civiletto, C McFarlane, ... Nature communications 10 (1), 5808, 2019 | 186 | 2019 |
| Myostatin-deficient mice exhibit reduced insulin resistance through activating the AMP-activated protein kinase signalling pathway C Zhang, C McFarlane, S Lokireddy, S Bonala, X Ge, S Masuda, ... Diabetologia 54, 1491-1501, 2011 | 175 | 2011 |
| Human myostatin negatively regulates human myoblast growth and differentiation C McFarlane, GZ Hui, WZW Amanda, HY Lau, S Lokireddy, G XiaoJia, ... American Journal of Physiology-Cell Physiology 301 (1), C195-C203, 2011 | 144 | 2011 |
| Identification of atrogin-1-targeted proteins during the myostatin-induced skeletal muscle wasting S Lokireddy, IW Wijesoma, SK Sze, C McFarlane, R Kambadur, ... American Journal of Physiology-Cell Physiology 303 (5), C512-C529, 2012 | 143 | 2012 |
| Myostatin: expanding horizons M Sharma, C McFarlane, R Kambadur, H Kukreti, S Bonala, S Srinivasan IUBMB life 67 (8), 589-600, 2015 | 138 | 2015 |
| Muscle-specific microRNA1 (miR1) targets heat shock protein 70 (HSP70) during dexamethasone-mediated atrophy H Kukreti, K Amuthavalli, A Harikumar, S Sathiyamoorthy, PZ Feng, ... Journal of Biological Chemistry 288 (9), 6663-6678, 2013 | 135 | 2013 |
| Myostatin promotes the wasting of human myoblast cultures through promoting ubiquitin-proteasome pathway-mediated loss of sarcomeric proteins S Lokireddy, V Mouly, G Butler-Browne, PD Gluckman, M Sharma, ... American Journal of Physiology-Cell Physiology 301 (6), C1316-C1324, 2011 | 127 | 2011 |
| Targeting the PI3K/Akt/mTOR pathway in hepatocellular carcinoma EJ Sun, M Wankell, P Palamuthusingam, C McFarlane, L Hebbard Biomedicines 9 (11), 1639, 2021 | 119 | 2021 |
| Mega roles of microRNAs in regulation of skeletal muscle health and disease M Sharma, PK Juvvuna, H Kukreti, C McFarlane Frontiers in physiology 5, 99484, 2014 | 107 | 2014 |
| Smad3 signaling is required for satellite cell function and myogenic differentiation of myoblasts X Ge, C McFarlane, A Vajjala, S Lokireddy, ZH Ng, CK Tan, NS Tan, ... Cell research 21 (11), 1591-1604, 2011 | 107 | 2011 |
| Myostatin inhibits rhabdomyosarcoma cell proliferation through an Rb-independent pathway B Langley, M Thomas, C McFarlane, S Gilmour, M Sharma, R Kambadur Oncogene 23 (2), 524-534, 2004 | 86 | 2004 |
| Proteolytic processing of myostatin is auto-regulated during myogenesis C McFarlane, B Langley, M Thomas, A Hennebry, E Plummer, G Nicholas, ... Developmental biology 283 (1), 58-69, 2005 | 84 | 2005 |
| Negative auto-regulation of myostatin expression is mediated by Smad3 and microRNA-27 C McFarlane, A Vajjala, H Arigela, S Lokireddy, XJ Ge, S Bonala, ... PloS one 9 (1), e87687, 2014 | 83 | 2014 |
| Loss of Parkin impairs mitochondrial function and leads to muscle atrophy N Peker, V Donipadi, M Sharma, C McFarlane, R Kambadur American Journal of Physiology-Cell Physiology, 2018 | 66 | 2018 |
| Lack of Smad3 signaling leads to impaired skeletal muscle regeneration X Ge, A Vajjala, C McFarlane, W Wahli, M Sharma, R Kambadur American Journal of Physiology-Endocrinology and Metabolism 303 (1), E90-E102, 2012 | 61 | 2012 |
