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Thomas L Ekstrom
Thomas L Ekstrom
Verified email at mayo.edu - Homepage
Title
Cited by
Cited by
Year
Robust activation of microhomology-mediated end joining for precision gene editing applications
H Ata, TL Ekstrom, G Martínez-Gálvez, CM Mann, AV Dvornikov, ...
PLoS genetics 14 (9), e1007652, 2018
752018
BRCA1 deficiency upregulates NNMT, which reprograms metabolism and sensitizes ovarian cancer cells to mitochondrial metabolic targeting agents
A Kanakkanthara, K Kurmi, TL Ekstrom, X Hou, ER Purfeerst, EP Heinzen, ...
Cancer research 79 (23), 5920-5929, 2019
532019
VLX600 disrupts homologous recombination and synergizes with PARP inhibitors and cisplatin by inhibiting histone lysine demethylases
TL Ekstrom, NM Pathoulas, AM Huehls, A Kanakkanthara, LM Karnitz
Molecular cancer therapeutics 20 (9), 1561-1571, 2021
122021
Repurposing ceritinib induces DNA damage and enhances PARP inhibitor responses in high-grade serous ovarian carcinoma
A Kanakkanthara, X Hou, TL Ekstrom, V Zanfagnin, AM Huehls, RL Kelly, ...
Cancer research 82 (2), 307-319, 2022
112022
Interactive enhancer hubs (iHUBs) mediate transcriptional reprogramming and adaptive resistance in pancreatic cancer
FH Hamdan, AM Abdelrahman, AP Kutschat, X Wang, TL Ekstrom, ...
Gut 72 (6), 1174-1185, 2023
52023
MAPK and NF-kappaB signaling converge on the epigenome to transcriptionally activate genes involved in pancreatic cancer metastasis
JE Aggrey-Fynn, FH Hamdan, AQ Wixom, TL Ekstrom, SA Johnsen
Cancer Research 83 (7_Supplement), 1481-1481, 2023
12023
Aiming for the Bullseye: Targeted activities decrease misconceptions related to enzyme function for undergraduate biochemistry students
CR Terrell, T Ekstrom, B Nguyen, K Nickodem
Biochemistry and Molecular Biology Education 49 (6), 904-916, 2021
12021
Toward Precision Molecular Surgery: Robust, Selective Induction of Microhomology-mediated End Joining in vivo
H Ata, TL Ekstrom, G Martínez-Gálvez, CM Mann, AV Dvornikov, ...
bioRxiv, 291187, 2018
12018
USP44 overexpression drives a MYC-like gene expression program in neuroblastoma through epigenetic reprogramming
TL Ekstrom, S Hussain, T Bedekovics, A Ali, L Paolini, H Mahmood, ...
Molecular Cancer Research, 2024
2024
GATA6 functions at distal enhancer regions to control classical pancreatic ductal carcinoma identity by promoting promoter-proximal pause release
T Ekstrom, R Rosok, S Johnsen
Pancreatology 23, e1, 2023
2023
USP44 DRIVES DISEASE AGGRESSION AND IS A POTENTIAL THERAPEUTIC TARGET IN NEUROBLASTOMA
S Hussain, T Bedekovics, Y Zhang, A Ali, L Paolini, T Ekstrom, ...
PEDIATRIC BLOOD & CANCER 69, S215-S216, 2022
2022
Addressing Enzyme‐Substrate Interaction Misconceptions with 3D Physical Models in an Undergraduate Biochemistry Course
TL Ekstrom, CR Terrell
The FASEB Journal 32, 663.5-663.5, 2018
2018
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