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Brian DeBosch
Brian DeBosch
Assistant Professor of Pediatrics and Cell Biology and Physiology
Verified email at kids.wustl.edu - Homepage
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Cited by
Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
106652021
Akt1 is required for physiological cardiac growth
B DeBosch, I Treskov, TS Lupu, C Weinheimer, A Kovacs, M Courtois, ...
Circulation 113 (17), 2097-2104, 2006
6632006
Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis
BJ DeBosch, MR Heitmeier, AL Mayer, CB Higgins, JR Crowley, TE Kraft, ...
Science signaling 9 (416), ra21-ra21, 2016
2632016
Akt2 regulates cardiac metabolism and cardiomyocyte survival
B DeBosch, N Sambandam, C Weinheimer, M Courtois, AJ Muslin
Journal of Biological Chemistry 281 (43), 32841-32851, 2006
2002006
Early-onset metabolic syndrome in mice lacking the intestinal uric acid transporter SLC2A9
BJ DeBosch, O Kluth, H Fujiwara, A Schürmann, K Moley
Nature communications 5 (1), 4642, 2014
1752014
SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy
AL Mayer, CB Higgins, MR Heitmeier, TE Kraft, X Qian, JR Crowley, ...
Scientific reports 6 (1), 38586, 2016
1032016
Glucose transporter 8 (GLUT8) mediates fructose-induced de novo lipogenesis and macrosteatosis
BJ DeBosch, Z Chen, JL Saben, BN Finck, KH Moley
Journal of Biological Chemistry 289 (16), 10989-10998, 2014
1032014
TRB3 function in cardiac endoplasmic reticulum stress
J Avery, S Etzion, BJ DeBosch, X Jin, TS Lupu, B Beitinjaneh, J Grand, ...
Circulation research 106 (9), 1516-1523, 2010
932010
Nutritional modulation of heart failure in mitochondrial pyruvate carrier–deficient mice
KS McCommis, A Kovacs, CJ Weinheimer, TM Shew, TR Koves, ...
Nature metabolism 2 (11), 1232-1247, 2020
842020
Glucose transporter 8 (GLUT8) regulates enterocyte fructose transport and global mammalian fructose utilization
BJ DeBosch, M Chi, KH Moley
Endocrinology 153 (9), 4181-4191, 2012
822012
Insulin signaling pathways and cardiac growth
BJ DeBosch, AJ Muslin
Journal of molecular and cellular cardiology 44 (5), 855-864, 2008
812008
Glucose transporter-8 (GLUT8) mediates glucose intolerance and dyslipidemia in high-fructose diet-fed male mice
BJ DeBosch, Z Chen, BN Finck, M Chi, KH Moley
Molecular endocrinology 27 (11), 1887-1896, 2013
642013
Trehalose causes low-grade lysosomal stress to activate TFEB and the autophagy-lysosome biogenesis response
SJ Jeong, J Stitham, TD Evans, X Zhang, A Rodriguez-Velez, YS Yeh, ...
Autophagy 17 (11), 3740-3752, 2021
622021
The 14-3-3τ phosphoserine-binding protein is required for cardiomyocyte survival
JMC Lau, X Jin, J Ren, J Avery, BJ DeBosch, I Treskov, TS Lupu, ...
Molecular and cellular biology, 2007
532007
Effects of insulin‐like growth factor‐1 on retinal endothelial cell glucose transport and proliferation
BJ DeBosch, E Baur, BK Deo, M Hiraoka, AK Kumagai
Journal of neurochemistry 77 (4), 1157-1167, 2001
482001
Tissue-specific fructose metabolism in obesity and diabetes
RN Helsley, F Moreau, MK Gupta, A Radulescu, B DeBosch, S Softic
Current diabetes reports 20, 1-16, 2020
472020
A maternal high-fat, high-sucrose diet induces transgenerational cardiac mitochondrial dysfunction independently of maternal mitochondrial inheritance
JLA Ferey, AL Boudoures, M Reid, A Drury, S Scheaffer, Z Modi, A Kovacs, ...
American Journal of Physiology-Heart and Circulatory Physiology 316 (5 …, 2019
472019
Using trehalose to prevent and treat metabolic function: effectiveness and mechanisms
Y Zhang, BJ DeBosch
Current Opinion in Clinical Nutrition & Metabolic Care 22 (4), 303-310, 2019
382019
Hepatic arginase 2 (Arg2) is sufficient to convey the therapeutic metabolic effects of fasting
Y Zhang, CB Higgins, HM Fortune, P Chen, AI Stothard, AL Mayer, ...
Nature communications 10 (1), 1587, 2019
342019
TFEB-dependent induction of thermogenesis by the hepatocyte SLC2A inhibitor trehalose
Y Zhang, CB Higgins, AL Mayer, IU Mysorekar, B Razani, MJ Graham, ...
Autophagy 14 (11), 1959-1975, 2018
312018
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