| Development of novel melanocortin receptor agonists based on the cyclic peptide framework of sunflower trypsin inhibitor-1 T Durek, PM Cromm, AM White, CI Schroeder, Q Kaas, J Weidmann, ... Journal of medicinal chemistry 61 (8), 3674-3684, 2018 | 37 | 2018 |
| Design of MC1R selective γ-MSH analogues with canonical amino acids leads to potency and pigmentation Y Zhou, S Mowlazadeh Haghighi, I Zoi, JR Sawyer, VJ Hruby, M Cai Journal of medicinal chemistry 60 (22), 9320-9329, 2017 | 21 | 2017 |
| Novel approaches to the design of bioavailable melanotropins Y Zhou, M Cai Expert opinion on drug discovery 12 (10), 1023-1030, 2017 | 19 | 2017 |
| Replacement of Arg with Nle and modified D-Phe in the core sequence of MSHs, Ac-His-D-Phe-Arg-Trp-NH2, leads to hMC1R selectivity and pigmentation SM Haghighi, Y Zhou, J Dai, JR Sawyer, VJ Hruby, M Cai European journal of medicinal chemistry 151, 815-823, 2018 | 18 | 2018 |
| Aged brains express less melanocortin receptors, which correlates with age-related decline of cognitive functions Y Zhou, MK Chawla, JL Rios-Monterrosa, L Wang, MA Zempare, ... Molecules 26 (20), 6266, 2021 | 12 | 2021 |
| Development of macrocyclic peptidomimetics containing constrained α, α-dialkylated amino acids with potent and selective activity at human melanocortin receptors F Merlino, Y Zhou, M Cai, A Carotenuto, AM Yousif, D Brancaccio, ... Journal of medicinal chemistry 61 (9), 4263-4269, 2018 | 12 | 2018 |
| Ghrelin receptor signaling in health and disease: a biased view JD Gross, Y Zhou, LS Barak, MG Caron Trends in Endocrinology & Metabolism 34 (2), 106-118, 2023 | 8 | 2023 |
| Development of ligand-drug conjugates targeting melanoma through the overexpressed melanocortin 1 receptor Y Zhou, S Mowlazadeh Haghighi, Z Liu, L Wang, VJ Hruby, M Cai ACS Pharmacology & Translational Science 3 (5), 921-930, 2020 | 8 | 2020 |
| Establishment of multi-stage intravenous self-administration paradigms in mice LM Slosky, A Pires, Y Bai, NB Clark, ER Hauser, JD Gross, F Porkka, ... Scientific reports 12 (1), 21422, 2022 | 7 | 2022 |
| Development of N-Acetylated Dipalmitoyl-S-Glyceryl Cysteine Analogs as Efficient TLR2/TLR6 Agonists Y Zhou, AH Banday, VJ Hruby, M Cai Molecules 24 (19), 3512, 2019 | 7 | 2019 |
| Discovery of a functionally selective ghrelin receptor (GHSR1a) ligand for modulating brain dopamine JD Gross, DW Kim, Y Zhou, D Jansen, LM Slosky, NB Clark, CR Ray, ... Proceedings of the National Academy of Sciences 119 (10), e2112397119, 2022 | 5 | 2022 |
| Measuring nonapoptotic caspase activity with a transgenic reporter in mice PJ Nicholls, TF Pack, NM Urs, S Kumar, Y Zhou, G Ichim, JD Ginzel, ... Eneuro 9 (5), 2022 | 4 | 2022 |
| Development of Selective Peptide Ligands Targeting Melanocortin Receptors for Melanoma Prevention and Therapy Y Zhou The University of Arizona., 2019 | 1 | 2019 |
| Ψ and χ Angle Constrains at the C-Terminus Trp Position of the Melanotropin Tetrapeptide Ac-His-d-Phe-Arg-Trp-NH2 Lead to Potent and Selective Agonists at … Y Zhou, S Mowlazadeh Haghighi, JR Sawyer, VJ Hruby, M Cai Journal of Medicinal Chemistry 66 (10), 6715-6724, 2023 | | 2023 |
| Conjugation of mcr1 ligand with cytotoxic drugs for treating skin cancer M Cai, VJ Hruby, Y Zhou US Patent App. 17/579,237, 2022 | | 2022 |
| Development of the MC1R Selective Ligands for the Melanoma Prevention M Cai, Y Zhou, SM Haghighi, V Hruby JOURNAL OF PEPTIDE SCIENCE 24, S69-S69, 2018 | | 2018 |
| DEVELOPMENT OF MC1R SELECTIVE LIGANDS AND CONJUGATES FOR THE PREVENTION OF SKIN CANCER AND MELANOMA IMAGING M Cai, Y Zhou, S Mowlazadeh, J Sawyer, VJ Hruby, S Svensson JOURNAL OF PEPTIDE SCIENCE 22, S44-S44, 2016 | | 2016 |
| Design, Synthesis and Test of Novel Lipidated Cysteine Analogs as Efficient TLR2/6 Agonists Y Zhou, AH Banday, M Cai, V Hruby | | |
| Conformationally Constrained Ac-His-D-Nal (2’)-Nle-Trp-NH2 Analogues Leads to Selective Melanotropins SM Haghighi, M Cai, Y Zhou, J Sawyer, B Lahtinen, C Chen, V Hruby | | |
| Design and Synthesis of a Novel Tetrapeptide with Improved Selectivity Towards the hMC1R JR Sawyer, SM Haghighi, Y Zhou, K McLeod, VJ Hruby, M Cai | | |
