| Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial CS Calfee, KL Delucchi, P Sinha, MA Matthay, J Hackett, M Shankar-Hari, ... The Lancet Respiratory Medicine 6 (9), 691-698, 2018 | 537 | 2018 |
| Essential role for the p110δ phosphoinositide 3-kinase in the allergic response K Ali, A Bilancio, M Thomas, W Pearce, AM Gilfillan, C Tkaczyk, N Kuehn, ... Nature 431 (7011), 1007-1011, 2004 | 506 | 2004 |
| A novel murine model of severe pulmonary arterial hypertension L Ciuclan, O Bonneau, M Hussey, N Duggan, AM Holmes, R Good, ... American journal of respiratory and critical care medicine 184 (10), 1171-1182, 2011 | 295 | 2011 |
| MicroRNA-143 activation regulates smooth muscle and endothelial cell crosstalk in pulmonary arterial hypertension L Deng, FJ Blanco, H Stevens, R Lu, A Caudrillier, M McBride, ... Circulation research 117 (10), 870-883, 2015 | 294 | 2015 |
| Activity of the estrogen-metabolizing enzyme cytochrome P450 1B1 influences the development of pulmonary arterial hypertension K White, AK Johansen, M Nilsen, L Ciuclan, E Wallace, L Paton, ... Circulation 126 (9), 1087-1098, 2012 | 158 | 2012 |
| The sphingosine 1-phosphate receptor agonist FTY720 differentially affects the sequestration of CD4+/CD25+ T-regulatory cells and enhances their functional activity E Sawicka, G Dubois, G Jarai, M Edwards, M Thomas, A Nicholls, R Albert, ... The Journal of Immunology 175 (12), 7973-7980, 2005 | 155 | 2005 |
| Sex-dependent influence of endogenous estrogen in pulmonary hypertension KM Mair, AF Wright, N Duggan, DJ Rowlands, MJ Hussey, S Roberts, ... American journal of respiratory and critical care medicine 190 (4), 456-467, 2014 | 151 | 2014 |
| MicroRNA-140-5p and SMURF1 regulate pulmonary arterial hypertension AMK Rothman, ND Arnold, JA Pickworth, J Iremonger, L Ciuclan, ... The Journal of clinical investigation 126 (7), 2495-2508, 2016 | 142 | 2016 |
| Activin-like kinase 5 (ALK5) mediates abnormal proliferation of vascular smooth muscle cells from patients with familial pulmonary arterial hypertension and is involved in the … M Thomas, C Docx, AM Holmes, S Beach, N Duggan, K England, ... The American journal of pathology 174 (2), 380-389, 2009 | 119 | 2009 |
| Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the LUNG SAFE prospective cohort study JG Laffey, F Madotto, G Bellani, T Pham, E Fan, L Brochard, P Amin, ... The Lancet Respiratory Medicine 5 (8), 627-638, 2017 | 115 | 2017 |
| CD8 T cells inhibit IgE via dendritic cell IL-12 induction that promotes Th1 T cell counter-regulation MJ Thomas, A Noble, E Sawicka, PW Askenase, DM Kemeny The Journal of Immunology 168 (1), 216-223, 2002 | 108 | 2002 |
| CD8+ T Cell Subsets and Chronic Obstructive Pulmonary Disease DM Kemeny, B Vyas, M Vukmanovic-Stejic, MJ Thomas, A Noble, LC Loh, ... American journal of respiratory and critical care medicine 160 (supplement_1 …, 1999 | 103 | 1999 |
| Predictors of participation of adolescents with cerebral palsy: A European multi-centre longitudinal study A Colver, HO Dickinson, M Marcelli, SI Michelsen, J Parkes, K Parkinson, ... Research in Developmental Disabilities 36, 551-564, 2015 | 91 | 2015 |
| Airway inflammation: chemokine‐induced neutrophilia and the class I phosphoinositide 3‐kinases MJ Thomas, A Smith, DH Head, L Milne, A Nicholls, W Pearce, ... European journal of immunology 35 (4), 1283-1291, 2005 | 91 | 2005 |
| Imatinib attenuates hypoxia-induced pulmonary arterial hypertension pathology via reduction in 5-hydroxytryptamine through inhibition of tryptophan hydroxylase 1 expression L Ciuclan, MJ Hussey, V Burton, R Good, N Duggan, S Beach, P Jones, ... American journal of respiratory and critical care medicine 187 (1), 78-89, 2013 | 79 | 2013 |
| Treatment with anti–gremlin 1 antibody ameliorates chronic hypoxia/SU5416–induced pulmonary arterial hypertension in mice L Ciuclan, KA Sheppard, L Dong, D Sutton, N Duggan, M Hussey, ... The American journal of pathology 183 (5), 1461-1473, 2013 | 69 | 2013 |
| Evolution of PI3Kγ and δ inhibitors for inflammatory and autoimmune diseases MWD Perry, R Abdulai, M Mogemark, J Petersen, MJ Thomas, B Valastro, ... Journal of Medicinal Chemistry 62 (10), 4783-4814, 2018 | 67 | 2018 |
| Early Th1/Th2 cell polarization in the absence of IL‐4 and IL‐12: T cell receptor signaling regulates the response to cytokines in CD4 and CD8 T cells A Noble, MJ Thomas, DM Kemeny European journal of immunology 31 (7), 2227-2235, 2001 | 66 | 2001 |
| Intermittent exposure to whole cigarette smoke alters the differentiation of primary small airway epithelial cells in the air-liquid interface culture JA Gindele, T Kiechle, K Benediktus, G Birk, M Brendel, F Heinemann, ... Scientific reports 10 (1), 6257, 2020 | 62 | 2020 |
| PI 3-kinase inhibition: a therapeutic target for respiratory disease PM Finan, MJ Thomas Biochemical Society Transactions 32 (2), 378-382, 2004 | 60 | 2004 |
