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Kristine Keon
Kristine Keon
Medical Student, University of Toronto
Verified email at mail.utoronto.ca
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Year
Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response
D Sharon, S Cathelin, S Mirali, JM Di Trani, DJ Yanofsky, KA Keon, ...
Science translational medicine 11 (516), eaax2863, 2019
1532019
Toosendanin, a novel potent vacuolar-type H+-translocating ATPase inhibitor, sensitizes cancer cells to chemotherapy by blocking protective autophagy
Y Dong, G Zhu, SF Wang, KA Keon, JL Rubinstein, SX Zeng, S Zhang, ...
International Journal of Biological Sciences 18 (7), 2684, 2022
162022
Coordinated conformational changes in the V1 complex during V-ATPase reversible dissociation
T Vasanthakumar, KA Keon, SA Bueler, MC Jaskolka, JL Rubinstein
Nature Structural & Molecular Biology 29 (5), 430-439, 2022
152022
CryoEM of endogenous mammalian V-ATPase interacting with the TLDc protein mEAK-7
YZ Tan, YM Abbas, JZ Wu, D Wu, KA Keon, GG Hesketh, SA Bueler, ...
Life Science Alliance 5 (11), 2022
142022
Structure of V-ATPase from citrus fruit
YZ Tan, KA Keon, R Abdelaziz, P Imming, W Schulze, K Schumacher, ...
Structure 30 (10), 1403-1410. e4, 2022
102022
Cryo-EM of the Yeast VO Complex Reveals Distinct Binding Sites for Macrolide V-ATPase Inhibitors
KA Keon, S Benlekbir, SH Kirsch, R Müller, JL Rubinstein
ACS Chemical Biology 17 (3), 619-628, 2022
32022
Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response. Sci Transl Med. 2019; 11 (516): eaax2863
D Sharon, S Cathelin, S Mirali, JM Di Trani, DJ Yanofsky, KA Keon, ...
32019
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