Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response D Sharon, S Cathelin, S Mirali, JM Di Trani, DJ Yanofsky, KA Keon, ... Science translational medicine 11 (516), eaax2863, 2019 | 153 | 2019 |
Toosendanin, a novel potent vacuolar-type H+-translocating ATPase inhibitor, sensitizes cancer cells to chemotherapy by blocking protective autophagy Y Dong, G Zhu, SF Wang, KA Keon, JL Rubinstein, SX Zeng, S Zhang, ... International Journal of Biological Sciences 18 (7), 2684, 2022 | 16 | 2022 |
Coordinated conformational changes in the V1 complex during V-ATPase reversible dissociation T Vasanthakumar, KA Keon, SA Bueler, MC Jaskolka, JL Rubinstein Nature Structural & Molecular Biology 29 (5), 430-439, 2022 | 15 | 2022 |
CryoEM of endogenous mammalian V-ATPase interacting with the TLDc protein mEAK-7 YZ Tan, YM Abbas, JZ Wu, D Wu, KA Keon, GG Hesketh, SA Bueler, ... Life Science Alliance 5 (11), 2022 | 14 | 2022 |
Structure of V-ATPase from citrus fruit YZ Tan, KA Keon, R Abdelaziz, P Imming, W Schulze, K Schumacher, ... Structure 30 (10), 1403-1410. e4, 2022 | 10 | 2022 |
Cryo-EM of the Yeast VO Complex Reveals Distinct Binding Sites for Macrolide V-ATPase Inhibitors KA Keon, S Benlekbir, SH Kirsch, R Müller, JL Rubinstein ACS Chemical Biology 17 (3), 619-628, 2022 | 3 | 2022 |
Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response. Sci Transl Med. 2019; 11 (516): eaax2863 D Sharon, S Cathelin, S Mirali, JM Di Trani, DJ Yanofsky, KA Keon, ... | 3 | 2019 |