关注
Luke Rogers
Luke Rogers
V.P. of Innovation, On Demand Pharmaceuticals
在 tcd.ie 的电子邮件经过验证
标题
引用次数
引用次数
年份
A robotic platform for flow synthesis of organic compounds informed by AI planning
CW Coley, DA Thomas III, JAM Lummiss, JN Jaworski, CP Breen, ...
Science 365 (6453), eaax1566, 2019
7122019
A graph-convolutional neural network model for the prediction of chemical reactivity
CW Coley, W Jin, L Rogers, TF Jamison, TS Jaakkola, WH Green, ...
Chemical science 10 (2), 370-377, 2019
6302019
Computer-assisted retrosynthesis based on molecular similarity
CW Coley, L Rogers, WH Green, KF Jensen
ACS central science 3 (12), 1237-1245, 2017
3092017
Continuous manufacturing–the Green Chemistry promise?
L Rogers, KF Jensen
Green chemistry 21 (13), 3481-3498, 2019
2682019
SCScore: synthetic complexity learned from a reaction corpus
CW Coley, L Rogers, WH Green, KF Jensen
Journal of chemical information and modeling 58 (2), 252-261, 2018
2532018
Continuous production of five active pharmaceutical ingredients in flexible plug-and-play modules: A demonstration campaign
L Rogers, N Briggs, R Achermann, A Adamo, M Azad, D Brancazio, ...
Organic Process Research & Development 24 (10), 2183-2196, 2020
622020
Computer-designed repurposing of chemical wastes into drugs
A Wołos, D Koszelewski, R Roszak, S Szymkuć, M Moskal, R Ostaszewski, ...
Nature 604 (7907), 668-676, 2022
352022
Continuous purification of active pharmaceutical ingredients utilizing polymer membrane surface wettability
J Imbrogno, L Rogers, DA Thomas, KF Jensen
Chemical communications 54 (1), 70-73, 2018
332018
PAT implementation on a mobile continuous pharmaceutical manufacturing system: real-time process monitoring with in-line FTIR and Raman spectroscopy
Y Miyai, A Formosa, C Armstrong, B Marquardt, L Rogers, T Roper
Organic Process Research & Development 25 (12), 2707-2717, 2021
312021
Micro-or nanorod and nanosphere structures derived from a series of phenyl-porphyrins
MHV Reddy, RM Al-Shammari, N Al-Attar, E Kennedy, L Rogers, S Lopez, ...
Physical Chemistry Chemical Physics 16 (9), 4386-4393, 2014
312014
Lead structures for applications in photodynamic therapy. 6. Temoporfin anti-inflammatory conjugates to target the tumor microenvironment for in vitro PDT
L Rogers, NN Sergeeva, E Paszko, GMF Vaz, MO Senge
PLoS One 10 (5), e0125372, 2015
282015
Synthesis and biological evaluation of Foscan® bile acid conjugates to target esophageal cancer cells
L Rogers, F Majer, NN Sergeeva, E Paszko, JF Gilmer, MO Senge
Bioorganic & medicinal chemistry letters 23 (9), 2495-2499, 2013
282013
RW HicklinP. P. PlehiersJ. ByingtonJ. S. PiottiW. H. GreenA. J. HartT. F. JamisonK. F. JensenA robotic platform for flow synthesis of organic compounds informed by AI planning
CW Coley, DA Thomas, JAM Lummiss, JN Jaworski, CP Breen, V Schultz, ...
Science 365, eaax1566, 2019
212019
On-demand continuous manufacturing of ciprofloxacin in portable plug-and-play factories: development of a highly efficient synthesis for ciprofloxacin
C Armstrong, Y Miyai, A Formosa, D Thomas, E Chen, T Hart, V Schultz, ...
Organic Process Research & Development 25 (7), 1524-1533, 2021
162021
Simple Porphyrin Desymmetrization: 5,10,15,20Tetrakis(3hydroxyphenyl)porphyrin (mTHPP) as a Gateway Molecule for Peripheral Functionalization
L Rogers, E BurkeMurphy, MO Senge
European Journal of Organic Chemistry 2014 (20), 4283-4294, 2014
162014
Preparation of triand hexasubstituted triptycene synthons by transition metal catalyzed crosscoupling reactions for postmodifications
C Moylan, L Rogers, YM Shaker, M Davis, HG Eckhardt, R Eckert, ...
European Journal of Organic Chemistry 2016 (1), 185-195, 2016
132016
The translocator protein as a potential molecular target for improved treatment efficacy in photodynamic therapy
L Rogers, MO Senge
Future Medicinal Chemistry 6 (7), 775-792, 2014
102014
Fractal structures in n-phenyl-porphyrin J-aggregate films
MHV Reddy, RM Al-Shammari, N Al-Attar, L Rogers, S Lopez, RJ Forster, ...
Materials Chemistry and Physics 143 (3), 963-968, 2014
92014
Leveraging first-principles and empirical models for disturbance detection in continuous pharmaceutical syntheses
C Armstrong, Y Miyai, A Formosa, P Kaushik, L Rogers, TD Roper
Journal of Flow Chemistry 13 (3), 275-291, 2023
32023
Pharmacy-on-Demand: A Continuous Revolution in Pharmaceutical Manufacturing?
L Rogers, R Achermann, A Adamo, M Behnam, R Beingessner, ...
2017 AIChE Annual Meeting, 2017
22017
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