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Luca Micci
Luca Micci
Verified email at merck.com
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Low levels of SIV infection in sooty mangabey central memory CD4+ T cells are associated with limited CCR5 expression
M Paiardini, B Cervasi, E Reyes-Aviles, L Micci, AM Ortiz, A Chahroudi, ...
Nature medicine 17 (7), 830-836, 2011
2142011
CTLA-4+ PD-1− memory CD4+ T cells critically contribute to viral persistence in antiretroviral therapy-suppressed, SIV-infected rhesus macaques
CS McGary, C Deleage, J Harper, L Micci, SP Ribeiro, S Paganini, ...
Immunity 47 (4), 776-788. e5, 2017
1602017
CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells
L Micci, X Alvarez, RI Iriele, AM Ortiz, ES Ryan, CS McGary, C Deleage, ...
PLoS pathogens 10 (10), e1004467, 2014
1202014
Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques
L Micci, ES Ryan, R Fromentin, SE Bosinger, JL Harper, T He, S Paganini, ...
The Journal of clinical investigation 125 (12), 4497-4513, 2015
1142015
Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression
DT Claiborne, JL Prince, E Scully, G Macharia, L Micci, B Lawson, ...
Proceedings of the National Academy of Sciences 112 (12), E1480-E1489, 2015
1132015
Maintenance of intestinal Th17 cells and reduced microbial translocation in SIV-infected rhesus macaques treated with interleukin (IL)-21
S Pallikkuth, L Micci, ZS Ende, RI Iriele, B Cervasi, B Lawson, CS McGary, ...
PLoS pathogens 9 (7), e1003471, 2013
1102013
CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption
J Harper, S Gordon, CN Chan, H Wang, E Lindemuth, C Galardi, ...
Nature medicine 26 (4), 519-528, 2020
762020
Paucity of IL-21–producing CD4+ T cells is associated with Th17 cell depletion in SIV infection of rhesus macaques
L Micci, B Cervasi, ZS Ende, RI Iriele, E Reyes-Aviles, C Vinton, J Else, ...
Blood, The Journal of the American Society of Hematology 120 (19), 3925-3935, 2012
732012
Loss of function of intestinal IL-17 and IL-22 producing cells contributes to inflammation and viral persistence in SIV-infected rhesus macaques
ES Ryan, L Micci, R Fromentin, S Paganini, CS McGary, K Easley, ...
PLoS pathogens 12 (2), e1005412, 2016
682016
Divergent CD4+ T memory stem cell dynamics in pathogenic and nonpathogenic simian immunodeficiency virus infections
EK Cartwright, CS McGary, B Cervasi, L Micci, B Lawson, STC Elliott, ...
The Journal of Immunology 192 (10), 4666-4673, 2014
642014
Multifunctional double-negative T cells in sooty mangabeys mediate T-helper functions irrespective of SIV infection
V Sundaravaradan, R Saleem, L Micci, MA Gasper, AM Ortiz, J Else, ...
PLoS pathogens 9 (6), e1003441, 2013
322013
Reconstitution of intestinal CD4 and Th17 T cells in antiretroviral therapy suppressed HIV-infected subjects: implication for residual immune activation from the results of a …
G d'Ettorre, S Baroncelli, L Micci, G Ceccarelli, M Andreotti, P Sharma, ...
PLoS One 9 (10), e109791, 2014
312014
IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques
J Harper, N Huot, L Micci, G Tharp, C King, P Rascle, N Shenvi, H Wang, ...
Nature Communications 12 (1), 2866, 2021
292021
The loss of CCR6+ and CD161+ CD4+ T-cell homeostasis contributes to disease progression in SIV-infected rhesus macaques
CS McGary, X Alvarez, S Harrington, B Cervasi, ES Ryan, RI Iriele, ...
Mucosal immunology 10 (4), 1082-1096, 2017
242017
Fingolimod retains cytolytic T cells and limits T follicular helper cell infection in lymphoid sites of SIV persistence
M Pino, S Paganini, C Deleage, K Padhan, JL Harper, CT King, L Micci, ...
PLoS pathogens 15 (10), e1008081, 2019
232019
Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy
J Harper, SP Ribeiro, CN Chan, M Aid, C Deleage, L Micci, M Pino, ...
The Journal of Clinical Investigation 132 (8), 2022
222022
Increased Stability and Limited Proliferation of CD4+ Central Memory T Cells Differentiate Nonprogressive Simian Immunodeficiency Virus (SIV) Infection of Sooty …
CS McGary, B Cervasi, A Chahroudi, L Micci, J Taaffe, T Meeker, ...
Journal of virology 88 (8), 4533-4542, 2014
222014
Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ART
M Pino, S Pereira Ribeiro, A Pagliuzza, K Ghneim, A Khan, E Ryan, ...
PLoS Pathogens 17 (8), e1009825, 2021
202021
Virologic and immunologic features of simian immunodeficiency virus control post-ART interruption in rhesus macaques
Z Strongin, L Micci, R Fromentin, J Harper, J McBrien, E Ryan, N Shenvi, ...
Journal of Virology 94 (14), 10.1128/jvi. 00338-20, 2020
172020
Systemic DPP4 activity is reduced during primary HIV‐1 infection and is associated with intestinal RORC+ CD4+ cell levels: a surrogate marker candidate of HIV‐induced …
MJ Ploquin, A Casrouge, Y Madec, N Noël, B Jacquelin, N Huot, D Duffy, ...
African Journal of Reproduction and Gynaecological Endoscopy 21 (7), 2018
172018
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