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Seokwon Jo
Seokwon Jo
Verified email at umn.edu
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Maternal low-protein diet on the last week of pregnancy contributes to insulin resistance and β-cell dysfunction in the mouse offspring
EU Alejandro, S Jo, B Akhaphong, PR Llacer, M Gianchandani, B Gregg, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2020
302020
Islet O-GlcNAcylation is required for lipid potentiation of insulin secretion through SERCA2
A Lockridge, S Jo, E Gustafson, N Damberg, R Mohan, M Olson, ...
Cell reports 31 (5), 2020
242020
eIF4G1 and carboxypeptidase E axis dysregulation in O-GlcNAc transferase–deficient pancreatic β-cells contributes to hyperproinsulinemia in mice
S Jo, A Lockridge, EU Alejandro
Journal of Biological Chemistry 294 (35), 13040-13050, 2019
242019
Role of nutrient-driven O-GlcNAc-post-translational modification in pancreatic exocrine and endocrine islet development
D Baumann, A Wong, B Akhaphong, S Jo, S Pritchard, R Mohan, ...
Development 147 (7), dev186643, 2020
222020
Reduced uterine perfusion pressure causes loss of pancreatic β-cell area but normal function in fetal rat offspring
B Akhaphong, A Lockridge, S Jo, R Mohan, JA Wilcox, CR Wing, JF Regal, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2018
202018
Disruption of O-linked N-acetylglucosamine signaling in placenta induces insulin sensitivity in female offspring
M Moore, N Avula, S Jo, M Beetch, EU Alejandro
International journal of molecular sciences 22 (13), 6918, 2021
172021
Placental mTOR complex 1 regulates fetal programming of obesity and insulin resistance in mice
B Akhaphong, DC Baumann, M Beetch, AD Lockridge, S Jo, A Wong, ...
JCI insight 6 (13), 2021
162021
OGT regulates mitochondrial biogenesis and function via diabetes susceptibility gene Pdx1
R Mohan, S Jo, A Lockridge, DA Ferrington, K Murray, A Eschenlauer, ...
Diabetes 70 (11), 2608-2625, 2021
142021
O-linked N-acetylglucosamine transferase (OGT) regulates pancreatic α-cell function in mice
A Essawy, S Jo, M Beetch, A Lockridge, E Gustafson, EU Alejandro
Journal of Biological Chemistry 296, 2021
132021
Maternal high-fat diet during pre-conception and gestation predisposes adult female offspring to metabolic dysfunction in mice
B Akhaphong, B Gregg, D Kumusoglu, K Singer, EU Alejandro
Frontiers in Endocrinology 12, 780300, 2022
102022
Translational factor eIF4G1 regulates glucose homeostasis and pancreatic β-cell function
S Jo, A Lockridge, R Mohan, N Esch, R Schlichting, N Panigrahy, ...
Diabetes 70 (1), 155-170, 2021
102021
Pancreatic β-cell O-GlcNAc transferase overexpression increases susceptibility to metabolic stressors in female mice
R Mohan, S Jo, E Da Sol Chung, E Oribamise, A Lockridge, ...
Cells 10 (10), 2801, 2021
82021
Sex differences in pancreatic β-cell physiology and glucose homeostasis in C57BL/6J mice
S Jo, M Beetch, E Gustafson, A Wong, E Oribamise, G Chung, S Vadrevu, ...
Journal of the Endocrine Society 7 (9), bvad099, 2023
72023
Metformin impairs trophoblast metabolism and differentiation in a dose-dependent manner
SK Nashif, RM Mahr, S Jena, S Jo, AB Nelson, D Sadowski, PA Crawford, ...
Frontiers in Cell and Developmental Biology 11, 1167097, 2023
72023
Nutrient Sensor mTOR and OGT: Orchestrators of Organelle Homeostasis in Pancreatic β‐Cells
N Esch, S Jo, M Moore, EU Alejandro
Journal of Diabetes Research 2020 (1), 8872639, 2020
72020
Pancreatic β-cell hyper-O-GlcNAcylation leads to impaired glucose homeostasis in vivo
S Jo, S Pritchard, A Wong, N Avula, A Essawy, J Hanover, EU Alejandro
Frontiers in Endocrinology 13, 1040014, 2022
42022
A computational bridge between traction force microscopy and tissue contraction
SM Flanary, S Jo, R Ravichandran, EU Alejandro, VH Barocas
Journal of Applied Physics 134 (7), 2023
22023
Placental insulin receptor transiently regulates glucose homeostasis in the adult mouse offspring of multiparous dams
G Chung, R Mohan, M Beetch, S Jo, EU Alejandro
Biomedicines 10 (3), 575, 2022
22022
Imeglimin to the Rescue: Enhanced CHOP/GADD34/eIF2α Signaling Axis Promotes β-Cell Survival
S Jo, EU Alejandro
Diabetes 71 (3), 376, 2022
22022
Reduction in O-GlcNAcylation mitigates the severity of inflammatory response in cerulein-induced acute pancreatitis in a mouse model
M Moore, N Avula, A Wong, M Beetch, S Jo, EU Alejandro
Biology 11 (3), 347, 2022
12022
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