Evidence for a common mechanism of SIRT1 regulation by allosteric activators BP Hubbard, AP Gomes, H Dai, J Li, AW Case, T Considine, TV Riera, ... Science 339 (6124), 1216-1219, 2013 | 658 | 2013 |
Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27) MT McCabe, AP Graves, G Ganji, E Diaz, WS Halsey, Y Jiang, ... Proceedings of the National Academy of Sciences 109 (8), 2989-2994, 2012 | 537 | 2012 |
Crystallographic structure of a small molecule SIRT1 activator-enzyme complex H Dai, AW Case, TV Riera, T Considine, JE Lee, Y Hamuro, H Zhao, ... Nature communications 6 (1), 7645, 2015 | 192 | 2015 |
A nucleolin-binding 3′ untranslated region element stabilizes β-globin mRNA in vivo Y Jiang, XS Xu, JE Russell Molecular and cellular biology 26 (6), 2419-2429, 2006 | 115 | 2006 |
Regulation of matrix metalloproteinase-9 (MMP-9) by translational efficiency in murine prostate carcinoma cells Y Jiang, RJ Muschel Cancer research 62 (6), 1910-1914, 2002 | 84 | 2002 |
Discovery of a novel 2, 6-disubstituted glucosamine series of potent and selective hexokinase 2 inhibitors H Lin, J Zeng, R Xie, MJ Schulz, R Tedesco, J Qu, KF Erhard, JF Mack, ... ACS medicinal chemistry letters 7 (3), 217-222, 2016 | 80 | 2016 |
Development and validation of reagents and assays for EZH2 peptide and nucleosome high-throughput screens E Diaz, CA Machutta, S Chen, Y Jiang, C Nixon, G Hofmann, D Key, ... Journal of biomolecular screening 17 (10), 1279-1292, 2012 | 58 | 2012 |
A687V EZH2 is a driver of histone H3 lysine 27 (H3K27) hypertrimethylation HM Ott, AP Graves, MB Pappalardi, M Huddleston, WS Halsey, ... Molecular cancer therapeutics 13 (12), 3062-3073, 2014 | 57 | 2014 |
Biochemical characterization of human HIF hydroxylases using HIF protein substrates that contain all three hydroxylation sites MB Pappalardi, DE McNulty, JD Martin, KE Fisher, Y Jiang, MC Burns, ... Biochemical Journal 436 (2), 363-369, 2011 | 46 | 2011 |
Biochemical characterization of human prolyl hydroxylase domain protein 2 variants associated with erythrocytosis MB Pappalardi, JD Martin, Y Jiang, MC Burns, H Zhao, T Ho, S Sweitzer, ... Biochemistry 47 (43), 11165-11167, 2008 | 27 | 2008 |
Meeting report: Proteases, extracellular matrix, and cancer: an AACR Special Conference in Cancer Research SJ Wall, Y Jiang, RJ Muschel, YA DeClerck Cancer research 63 (15), 4750-4755, 2003 | 17 | 2003 |
A potential regulatory role for mRNA secondary structures within the prothrombin 3'UTR X Liu, Y Jiang, JE Russell Thrombosis research 126 (2), 130-136, 2010 | 12 | 2010 |
Small molecule-mediated allosteric activation of the base excision repair enzyme 8-oxoguanine DNA glycosylase and its impact on mitochondrial function G Tian, SR Katchur, Y Jiang, J Briand, M Schaber, C Kreatsoulas, ... Scientific Reports 12 (1), 14685, 2022 | 9 | 2022 |
Methyltransferases prefer monomer over core-trimmed nucleosomes as in vitro substrates Y Jiang, JL Schneck, M Grimes, AN Taylor, W Hou, SH Thrall, ... Analytical biochemistry 415 (1), 84-86, 2011 | 8 | 2011 |
Component co-expression and purification of recombinant human pyruvate dehydrogenase complex from baculovirus infected SF9 cells Y Jiang, J Wang, G Zhang, K Oza, L Myers, MA Holbert, S Sweitzer Protein Expression and Purification 97, 9-16, 2014 | 3 | 2014 |
Determination of label efficiency and label degree of critical reagents by LC-MS and native MS K Carle, JF Kellie, GR Gunn, Y Jiang Analytical Biochemistry 664, 115033, 2023 | 2 | 2023 |
Modular protein Ligation: A new paradigm as a Reagent platform for pre-clinical Drug Discovery R Matico, LM Szewczuk, B Pietrak, S Chen, E Dul, WG Bonnette, ... Scientific Reports 9 (1), 13078, 2019 | 2 | 2019 |
Simple method to determine the concentration and incorporation ratio of ruthenium-labeled antibodies Y Jiang, AP Mayer, K Carle, R Mozaffari, G Gunn Bioanalysis 14 (1), 19-28, 2021 | 1 | 2021 |
Development of a high-content imaging assay for screening compound aggregation Y Jiang, A Hoffman, G Quinque, WG Bonnette, LM Szewczuk, MA Holbert, ... Analytical biochemistry 559, 30-33, 2018 | 1 | 2018 |
Small Molecule-Mediated Allosteric Activation of the Base Excision Repair Enzyme 8-Oxoguanine DNA Glycosylase: Impact on Mitochondrial Function G Tian, S Katchur, Y Jiang, J Briand, M Schaber, C Kreatsoulas, ... | | 2022 |