A comparative study of disintegration actions of various disintegrants using Kohonen's self-organizing maps Y Onuki, A Kosugi, M Hamaguchi, Y Marumo, S Kumada, D Hirai, J Ikeda, ... Journal of Drug Delivery Science and Technology 43, 141-148, 2018 | 35 | 2018 |
1H NMR relaxation study to evaluate the crystalline state of active pharmaceutical ingredients containing solid dosage forms using time domain NMR K Okada, D Hirai, S Kumada, A Kosugi, Y Hayashi, Y Onuki Journal of Pharmaceutical Sciences 108 (1), 451-456, 2019 | 34 | 2019 |
Latent structure analysis in pharmaceutical formulations using Kohonen's self-organizing map and a Bayesian network S Kikuchi, Y Onuki, A Yasuda, Y Hayashi, K Takayama Journal of pharmaceutical sciences 100 (3), 964-975, 2011 | 27 | 2011 |
Modeling of quantitative relationships between physicochemical properties of active pharmaceutical ingredients and tensile strength of tablets using a boosted tree Y Hayashi, T Oishi, K Shirotori, Y Marumo, A Kosugi, S Kumada, D Hirai, ... Drug Development and Industrial Pharmacy 44 (7), 1090-1098, 2018 | 25 | 2018 |
Prediction of tablet characteristics from residual stress distribution estimated by the finite element method Y Hayashi, T Miura, T Shimada, Y Onuki, Y Obata, K Takayama Journal of Pharmaceutical Sciences 102 (10), 3678-3686, 2013 | 24 | 2013 |
MRI as a promising tool for evaluation of the stability of cosmetic emulsions Y Onuki, C Kida, C Funatani, Y Hayashi, K Takayama International journal of cosmetic science 38 (3), 272-278, 2016 | 21 | 2016 |
A novel approach to establishing the design space for the oral formulation manufacturing process T Norioka, Y Hayashi, Y Onuki, H Andou, D Tsunashima, K Yamashita, ... Chemical and Pharmaceutical Bulletin 61 (1), 39-49, 2013 | 20 | 2013 |
Reliability evaluation of nonlinear design space in pharmaceutical product development Y Hayashi, S Kikuchi, Y Onuki, K Takayama Journal of pharmaceutical sciences 101 (1), 333-341, 2012 | 20 | 2012 |
Application of machine learning to a material library for modeling of relationships between material properties and tablet properties Y Hayashi, Y Nakano, Y Marumo, S Kumada, K Okada, Y Onuki International Journal of Pharmaceutics 609, 121158, 2021 | 19 | 2021 |
Classification of scanning electron microscope images of pharmaceutical excipients using deep convolutional neural networks with transfer learning H Iwata, Y Hayashi, A Hasegawa, K Terayama, Y Okuno International Journal of Pharmaceutics: X 4, 100135, 2022 | 16 | 2022 |
Effect of the molecular mobility of water adsorbed by disintegrants on storage-induced hydrolytic degradation of acetylsalicylic acid incorporated into tablets under humid … K Ougi, K Okada, KH Leong, Y Hayashi, S Kumada, Y Onuki European Journal of Pharmaceutical Sciences 154, 105502, 2020 | 16 | 2020 |
T2 relaxation study to evaluate the crystalline state of indomethacin containing solid dispersions using time-domain NMR K Okada, D Hirai, Y Hayashi, S Kumada, A Kosugi, Y Onuki Chemical and Pharmaceutical Bulletin 67 (6), 580-586, 2019 | 16 | 2019 |
Numerical investigation of the residual stress distribution of flat-faced and convexly curved tablets using the finite element method S Otoguro, Y Hayashi, T Miura, N Uehara, S Utsumi, Y Onuki, Y Obata, ... Chemical and Pharmaceutical Bulletin 63 (11), 890-900, 2015 | 16 | 2015 |
Real-time monitoring of the drying of extruded granules in a fluidised bed using near infrared spectroscopy and kinetic evaluation of the drying process Y Hayashi, T Sato, M Otsuka Journal of Near Infrared Spectroscopy 21 (2), 107-115, 2013 | 16 | 2013 |
Effect of process variables on the Drucker–Prager cap model and residual stress distribution of tablets estimated by the finite element method Y Hayashi, S Otoguro, T Miura, Y Onuki, Y Obata, K Takayama Chemical and Pharmaceutical Bulletin 62 (11), 1062-1072, 2014 | 15 | 2014 |
Latent structure analysis of the process variables and pharmaceutical responses of an orally disintegrating tablet Y Hayashi, E Oshima, J Maeda, Y Onuki, Y Obata, K Takayama Chemical and Pharmaceutical Bulletin 60 (11), 1419-1425, 2012 | 15 | 2012 |
Creation of novel large dataset comprising several granulation methods and the prediction of tablet properties from critical material attributes and critical process parameters … T Oishi, Y Hayashi, M Noguchi, F Yano, S Kumada, K Takayama, K Okada, ... International journal of pharmaceutics 577, 119083, 2020 | 13 | 2020 |
Membrane microdomain structures of liposomes and their contribution to the cellular uptake efficiency into HeLa cells Y Onuki, Y Obata, K Kawano, H Sano, R Matsumoto, Y Hayashi, ... Molecular Pharmaceutics 13 (2), 369-378, 2016 | 13 | 2016 |
Nondestructive investigation of the agglomeration process for nanosuspensions via NMR relaxation of water molecules K Okada, Y Hayashi, S Kumada, Y Onuki European Journal of Pharmaceutical Sciences 164, 105908, 2021 | 12 | 2021 |
A novel approach to evaluate amorphous-to-crystalline transformation of active pharmaceutical ingredients in solid dispersion using time-domain NMR K Okada, D Hirai, Y Hayashi, S Kumada, A Kosugi, Y Onuki Chemical and Pharmaceutical Bulletin 67 (3), 265-270, 2019 | 11 | 2019 |