De novo design of potent and selective mimics of IL-2 and IL-15 DA Silva, S Yu, UY Ulge, JB Spangler, KM Jude, C Labão-Almeida, LR Ali, ... Nature 565 (7738), 186-191, 2019 | 417 | 2019 |
Anti–CTLA-4 therapy requires an Fc domain for efficacy JR Ingram, OS Blomberg, M Rashidian, L Ali, S Garforth, E Fedorov, ... Proceedings of the National Academy of Sciences 115 (15), 3912-3917, 2018 | 140 | 2018 |
Localized CD47 blockade enhances immunotherapy for murine melanoma JR Ingram, OS Blomberg, JT Sockolosky, L Ali, FI Schmidt, N Pishesha, ... Proceedings of the National Academy of Sciences 114 (38), 10184-10189, 2017 | 119 | 2017 |
Targeting cytokine therapy to the pancreatic tumor microenvironment using PD-L1–specific VHHs M Dougan, JR Ingram, HJ Jeong, MM Mosaheb, PT Bruck, L Ali, ... Cancer immunology research 6 (4), 389-401, 2018 | 80 | 2018 |
Inhibition of CDK4/6 promotes CD8 T-cell memory formation M Heckler, LR Ali, E Clancy-Thompson, L Qiang, KS Ventre, P Lenehan, ... Cancer discovery 11 (10), 2564-2581, 2021 | 71 | 2021 |
Immune receptor inhibition through enforced phosphatase recruitment RA Fernandes, L Su, Y Nishiga, J Ren, AM Bhuiyan, N Cheng, CJ Kuo, ... Nature 586 (7831), 779-784, 2020 | 67 | 2020 |
cIAP1/2 antagonism eliminates MHC class I–negative tumors through T cell–dependent reprogramming of mononuclear phagocytes K Roehle, L Qiang, KS Ventre, D Heid, LR Ali, P Lenehan, M Heckler, ... Science translational medicine 13 (594), eabf5058, 2021 | 32 | 2021 |
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy A Quijano-Rubio, AM Bhuiyan, H Yang, I Leung, E Bello, LR Ali, ... Nature biotechnology 41 (4), 532-540, 2023 | 31 | 2023 |
IAP antagonists enhance cytokine production from mouse and human iNKT cells E Clancy-Thompson, L Ali, PT Bruck, MA Exley, RS Blumberg, G Dranoff, ... Cancer immunology research 6 (1), 25-35, 2018 | 28 | 2018 |
Altered Binding of Tumor Antigenic Peptides to MHC Class I Affects CD8+ T Cell–Effector Responses E Clancy-Thompson, CA Devlin, PM Tyler, MM Servos, LR Ali, KS Ventre, ... Cancer immunology research 6 (12), 1524-1536, 2018 | 22 | 2018 |
Neoleukin-2 enhances anti-tumour immunity downstream of peptide vaccination targeted by an anti-MHC class II VHH SJ Crowley, PT Bruck, MA Bhuiyan, A Mitchell-Gears, MJ Walsh, ... Open Biology 10 (2), 190235, 2020 | 14 | 2020 |
Trusted status transfer between associated devices JC Wilson, L Ali, A Arromratana US Patent 10,063,540, 2018 | 13 | 2018 |
Targeting cytokine therapy to the pancreatic tumor microenvironment using PD-L1–specific VHHs. Cancer Immunol. Res. 2018; 6: 389–401. doi: 10.1158/2326-6066 M Dougan, JR Ingram, HJ Jeong, MM Mosaheb, PT Bruck, L Ali, ... CIR-17-0495.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 13 | |
Shared data within a family CD Espinosa, L Ali, CM Tokar, E Voas, GB Fullerton, KE Ridsdale, ... US Patent App. 14/724,714, 2015 | 12 | 2015 |
Transforming growth factor-Β blockade in pancreatic cancer enhances sensitivity to combination chemotherapy L Qiang, MT Hoffman, LR Ali, JI Castillo, L Kageler, A Temesgen, ... Gastroenterology 165 (4), 874-890. e10, 2023 | 11 | 2023 |
Early outcomes and complications following cardiac surgery in patients testing positive for coronavirus disease 2019: An international cohort study TCIR Network, COVIDSurg Collaborative The Journal of thoracic and cardiovascular surgery 162 (2), e355, 2021 | 11 | 2021 |
Tissue eosinophils express the IL‐33 receptor ST2 and type 2 cytokines in patients with eosinophilic esophagitis AM Uchida, PJ Lenehan, P Vimalathas, KC Miller, M Valencia‐Yang, ... Allergy 77 (2), 656-660, 2022 | 10 | 2022 |
Replicability of neural responses to speech accent is driven by study design and analytical parameters CB Strauber, LR Ali, T Fujioka, C Thille, BD McCandliss Scientific reports 11 (1), 4777, 2021 | 9 | 2021 |
PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer LR Ali, AC Garrido-Castro, PJ Lenehan, N Bollenrucher, CT Stump, ... Journal of Experimental Medicine 220 (4), 2023 | 8 | 2023 |
IFNγ is a central node of cancer immune equilibrium MJ Walsh, CT Stump, R Kureshi, P Lenehan, LR Ali, M Dougan, ... Cell reports 42 (3), 2023 | 8 | 2023 |