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Xin Tong
Xin Tong
Harvard Medical School
Verified email at mgh.harvard.edu
Title
Cited by
Cited by
Year
Glycosynthase mutants of endoglycosidase S2 show potent transglycosylation activity and remarkably relaxed substrate specificity for antibody glycosylation remodeling
T Li, X Tong, Q Yang, JP Giddens, LX Wang
Journal of Biological Chemistry 291 (32), 16508-16518, 2016
1252016
Glycoengineering of antibodies for modulating functions
LX Wang, X Tong, C Li, JP Giddens, T Li
Annual review of biochemistry 88, 433-459, 2019
1192019
Omicron variant Spike-specific antibody binding and Fc activity are preserved in recipients of mRNA or inactivated COVID-19 vaccines
YC Bartsch, X Tong, J Kang, MJ Avendaño, EF Serrano, T García-Salum, ...
Science translational medicine 14 (642), eabn9243, 2022
882022
One-pot enzymatic glycan remodeling of a therapeutic monoclonal antibody by endoglycosidase S (Endo-S) from Streptococcus pyogenes
X Tong, T Li, J Orwenyo, C Toonstra, LX Wang
Bioorganic & medicinal chemistry 26 (7), 1347-1355, 2018
222018
Preserved Omicron Spike specific antibody binding and Fc-recognition across COVID-19 vaccine platforms
Y Bartsch, X Tong, J Kang, MJ Avendaño, EF Serrano, T García-Salum, ...
Medrxiv, 2021
212021
Glycosylation-dependent opsonophagocytic activity of staphylococcal protein A antibodies
X Chen, M Shi, X Tong, HK Kim, LX Wang, O Schneewind, D Missiakas
Proceedings of the National Academy of Sciences 117 (37), 22992-23000, 2020
202020
Generation and Comparative Kinetic Analysis of New Glycosynthase Mutants from Streptococcus pyogenes Endoglycosidases for Antibody Glycoengineering
X Tong, T Li, C Li, LX Wang
Biochemistry 57 (35), 5239-5246, 2018
172018
Efficacy of mRNA-1273 and Novavax ancestral or BA. 1 spike booster vaccines against SARS-CoV-2 BA. 5 infection in nonhuman primates
NK Routhu, SD Stampfer, L Lai, A Akhtar, X Tong, D Yuan, TM Chicz, ...
Science Immunology 8 (88), eadg7015, 2023
152023
Exploring a combined Escherichia coli-based glycosylation and in vitro transglycosylation approach for expression of glycosylated interferon alpha
SK Prabhu, Q Yang, X Tong, LX Wang
Bioorganic & medicinal chemistry 33, 116037, 2021
122021
Simple, rapidly electroassembled thiolated PEG‐based sensor interfaces enable rapid interrogation of antibody titer and glycosylation
D Motabar, J Li, S Wang, CY Tsao, X Tong, LX Wang, GF Payne, ...
Biotechnology and Bioengineering 118 (7), 2744-2758, 2021
92021
Waning and boosting of antibody Fc-effector functions upon SARS-CoV-2 vaccination
X Tong, RP McNamara, MJ Avendaño, EF Serrano, T García-Salum, ...
Nature Communications 14 (1), 4174, 2023
52023
Waning immunity and IgG4 responses following bivalent mRNA boosting
N Lasrado, AY Collier, J Miller, NP Hachmann, J Liu, T Anand, ...
Science Advances 10 (8), eadj9945, 2024
22024
Synthesis, binding affinity, and inhibitory capacity of cyclodextrin-based multivalent glycan ligands for human galectin-3
C Ou, C Li, C Feng, X Tong, GR Vasta, LX Wang
Bioorganic & medicinal chemistry 72, 116974, 2022
22022
Distinct Functional Humoral Immune Responses Are Induced after Live Attenuated and Inactivated Seasonal Influenza Vaccination
X Tong, Y Deng, D Cizmeci, L Fontana, MA Carlock, HB Hanley, ...
The Journal of Immunology 212 (1), 24-34, 2024
12024
Endo-S2 mutants as glycosynthases, method of making and use for glycoengineering of glycoproteins
LX Wang, Q Yang, T Li, X Tong
US Patent 11,845,970, 2023
12023
Concurrent administration of COVID-19 and influenza vaccines enhances Spike-specific antibody responses
SE Barouch, TM Chicz, R Blanc, DR Barbati, LJ Parker, X Tong, ...
bioRxiv, 2023
12023
Waning and boosting of functional humoral immunity to SARS-CoV-2
X Tong, RP McNamara, MJ Avendaño, EF Serrano, T García-Salum, ...
bioRxiv, 2022
12022
Endo-S2 mutants as glycosynthases, method of making and use for glycoengineering of glycoproteins
LX Wang, Q Yang, T Li, X Tong
US Patent 11,008,601, 2021
12021
A facile synthesis of a complex type N-glycan thiazoline as an effective inhibitor against the antibody-deactivating endo-β-N-acetylglucosaminidases
C Li, S Zhu, X Tong, C Ou, LX Wang
Journal of carbohydrate chemistry 36 (8-9), 336-346, 2017
12017
Compartment-Specific Antibody Correlates of Protection to SARS-CoV-2 Omicron in Macaques
X Tong, Q Wang, W Jung, TM Chicz, R Blanc, LJ Parker, DH Barouch, ...
bioRxiv, 2024.03. 01.582951, 2024
2024
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