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Nicholas Izzo
Nicholas Izzo
Independent Consultant
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Year
HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte
WC Claycomb, NA Lanson Jr, BS Stallworth, DB Egeland, JB Delcarpio, ...
Proceedings of the National Academy of Sciences 95 (6), 2979-2984, 1998
18451998
In vitro exposure to 0.5% bupivacaine is cytotoxic to bovine articular chondrocytes
CR Chu, NJ Izzo, NE Papas, FH Fu
Arthroscopy: The Journal of Arthroscopic & Related Surgery 22 (7), 693-699, 2006
2922006
The in vitro effects of bupivacaine on articular chondrocytes
CR Chu, NJ Izzo, CH Coyle, NE Papas, A Logar
The Journal of Bone & Joint Surgery British Volume 90 (6), 814-820, 2008
2632008
Hypertrophic stimuli induce transforming growth factor-beta 1 expression in rat ventricular myocytes.
N Takahashi, A Calderone, NJ Izzo, TM Mäki, JD Marsh, WS Colucci
The Journal of clinical investigation 94 (4), 1470-1476, 1994
2571994
Pressure-and volume-induced left ventricular hypertrophies are associated with distinct myocyte phenotypes and differential induction of peptide growth factor mRNAs
A Calderone, N Takahashi, NJ Izzo Jr, CM Thaik, WS Colucci
Circulation 92 (9), 2385-2390, 1995
2551995
Controlled release of bioactive TGF-β1 from microspheres embedded within biodegradable hydrogels
AJ DeFail, CR Chu, N Izzo, KG Marra
Biomaterials 27 (8), 1579-1585, 2006
2472006
The clinical promise of biomarkers of synapse damage or loss in Alzheimer’s disease
M Colom-Cadena, T Spires-Jones, H Zetterberg, K Blennow, A Caggiano, ...
Alzheimer's research & therapy 12, 1-12, 2020
2352020
Alzheimer's therapeutics targeting amyloid beta 1–42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity
NJ Izzo, J Xu, C Zeng, MJ Kirk, K Mozzoni, C Silky, C Rehak, R Yurko, ...
PloS one 9 (11), e111899, 2014
2032014
Alzheimer's therapeutics targeting amyloid beta 1–42 oligomers I: Abeta 42 oligomer binding to specific neuronal receptors is displaced by drug candidates that improve …
NJ Izzo, A Staniszewski, L To, M Fa, AF Teich, F Saeed, H Wostein, ...
PloS one 9 (11), e111898, 2014
1702014
Adenoviral-mediated transfer of TGF-β1 but not IGF-1 induces chondrogenic differentiation of human mesenchymal stem cells in pellet cultures
K Kawamura, CR Chu, S Sobajima, PD Robbins, FH Fu, NJ Izzo, ...
Experimental hematology 33 (8), 865-872, 2005
1442005
Role of calcium in endothelium-dependent relaxation of arterial smooth muscle
MJ Peach, HA Singer, NJ Izzo Jr, AL Loeb
The American journal of cardiology 59 (2), A35-A43, 1987
1281987
Clinical diagnosis of potentially treatable early articular cartilage degeneration using optical coherence tomography
CR Chu, NJ Izzo, JJ Irrgang, M Ferretti, RK Studer
Journal of biomedical optics 12 (5), 051703-051703-6, 2007
1032007
Regulation of calcium channel expression in neonatal myocytes by catecholamines.
T Maki, EJ Gruver, AJ Davidoff, N Izzo, D Toupin, W Colucci, AR Marks, ...
The Journal of clinical investigation 97 (3), 656-663, 1996
1021996
Sustained hypoxia enhances chondrocyte matrix synthesis
CH Coyle, NJ Izzo, CR Chu
Journal of Orthopaedic Research 27 (6), 793-799, 2009
962009
A phase 1 clinical trial of the sigma-2 receptor complex allosteric antagonist CT1812, a novel therapeutic candidate for Alzheimer's disease
M Grundman, R Morgan, JD Lickliter, LS Schneider, S DeKosky, NJ Izzo, ...
Alzheimer's & Dementia: Translational Research & Clinical Interventions 5, 20-26, 2019
892019
Alpha 1-adrenergic receptor mRNA level is regulated by norepinephrine in rabbit aortic smooth muscle cells.
NJ Izzo Jr, CE Seidman, S Collins, WS Colucci
Proceedings of the National Academy of Sciences 87 (16), 6268-6271, 1990
801990
Tonic activation of hypoxia‐inducible factor 1α in avascular articular cartilage and implications for metabolic homeostasis
PU Brucker, NJ Izzo, CR Chu
Arthritis & Rheumatism: Official Journal of the American College of …, 2005
712005
Endothelium-derived relaxing factor release associated with increased endothelial cell inositol trisphosphate and intracellular calcium
AL Loeb, NJ Izzo Jr, RM Johnson, JC Garrison, MJ Peach
The American journal of cardiology 62 (11), 36-40, 1988
711988
Preclinical and clinical biomarker studies of CT1812: A novel approach to Alzheimer's disease modification
NJ Izzo, CM Yuede, KM LaBarbera, CS Limegrover, C Rehak, R Yurko, ...
Alzheimer's & Dementia 17 (8), 1365-1382, 2021
552021
Medicinal uses of hydrazones
JIK Almstead, NJ Izzo, DR Jones, RM Kawamoto
US Patent 6,660,737, 2003
532003
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