HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte WC Claycomb, NA Lanson Jr, BS Stallworth, DB Egeland, JB Delcarpio, ... Proceedings of the National Academy of Sciences 95 (6), 2979-2984, 1998 | 1845 | 1998 |
In vitro exposure to 0.5% bupivacaine is cytotoxic to bovine articular chondrocytes CR Chu, NJ Izzo, NE Papas, FH Fu Arthroscopy: The Journal of Arthroscopic & Related Surgery 22 (7), 693-699, 2006 | 292 | 2006 |
The in vitro effects of bupivacaine on articular chondrocytes CR Chu, NJ Izzo, CH Coyle, NE Papas, A Logar The Journal of Bone & Joint Surgery British Volume 90 (6), 814-820, 2008 | 263 | 2008 |
Hypertrophic stimuli induce transforming growth factor-beta 1 expression in rat ventricular myocytes. N Takahashi, A Calderone, NJ Izzo, TM Mäki, JD Marsh, WS Colucci The Journal of clinical investigation 94 (4), 1470-1476, 1994 | 257 | 1994 |
Pressure-and volume-induced left ventricular hypertrophies are associated with distinct myocyte phenotypes and differential induction of peptide growth factor mRNAs A Calderone, N Takahashi, NJ Izzo Jr, CM Thaik, WS Colucci Circulation 92 (9), 2385-2390, 1995 | 255 | 1995 |
Controlled release of bioactive TGF-β1 from microspheres embedded within biodegradable hydrogels AJ DeFail, CR Chu, N Izzo, KG Marra Biomaterials 27 (8), 1579-1585, 2006 | 247 | 2006 |
The clinical promise of biomarkers of synapse damage or loss in Alzheimer’s disease M Colom-Cadena, T Spires-Jones, H Zetterberg, K Blennow, A Caggiano, ... Alzheimer's research & therapy 12, 1-12, 2020 | 235 | 2020 |
Alzheimer's therapeutics targeting amyloid beta 1–42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity NJ Izzo, J Xu, C Zeng, MJ Kirk, K Mozzoni, C Silky, C Rehak, R Yurko, ... PloS one 9 (11), e111899, 2014 | 203 | 2014 |
Alzheimer's therapeutics targeting amyloid beta 1–42 oligomers I: Abeta 42 oligomer binding to specific neuronal receptors is displaced by drug candidates that improve … NJ Izzo, A Staniszewski, L To, M Fa, AF Teich, F Saeed, H Wostein, ... PloS one 9 (11), e111898, 2014 | 170 | 2014 |
Adenoviral-mediated transfer of TGF-β1 but not IGF-1 induces chondrogenic differentiation of human mesenchymal stem cells in pellet cultures K Kawamura, CR Chu, S Sobajima, PD Robbins, FH Fu, NJ Izzo, ... Experimental hematology 33 (8), 865-872, 2005 | 144 | 2005 |
Role of calcium in endothelium-dependent relaxation of arterial smooth muscle MJ Peach, HA Singer, NJ Izzo Jr, AL Loeb The American journal of cardiology 59 (2), A35-A43, 1987 | 128 | 1987 |
Clinical diagnosis of potentially treatable early articular cartilage degeneration using optical coherence tomography CR Chu, NJ Izzo, JJ Irrgang, M Ferretti, RK Studer Journal of biomedical optics 12 (5), 051703-051703-6, 2007 | 103 | 2007 |
Regulation of calcium channel expression in neonatal myocytes by catecholamines. T Maki, EJ Gruver, AJ Davidoff, N Izzo, D Toupin, W Colucci, AR Marks, ... The Journal of clinical investigation 97 (3), 656-663, 1996 | 102 | 1996 |
Sustained hypoxia enhances chondrocyte matrix synthesis CH Coyle, NJ Izzo, CR Chu Journal of Orthopaedic Research 27 (6), 793-799, 2009 | 96 | 2009 |
A phase 1 clinical trial of the sigma-2 receptor complex allosteric antagonist CT1812, a novel therapeutic candidate for Alzheimer's disease M Grundman, R Morgan, JD Lickliter, LS Schneider, S DeKosky, NJ Izzo, ... Alzheimer's & Dementia: Translational Research & Clinical Interventions 5, 20-26, 2019 | 89 | 2019 |
Alpha 1-adrenergic receptor mRNA level is regulated by norepinephrine in rabbit aortic smooth muscle cells. NJ Izzo Jr, CE Seidman, S Collins, WS Colucci Proceedings of the National Academy of Sciences 87 (16), 6268-6271, 1990 | 80 | 1990 |
Tonic activation of hypoxia‐inducible factor 1α in avascular articular cartilage and implications for metabolic homeostasis PU Brucker, NJ Izzo, CR Chu Arthritis & Rheumatism: Official Journal of the American College of …, 2005 | 71 | 2005 |
Endothelium-derived relaxing factor release associated with increased endothelial cell inositol trisphosphate and intracellular calcium AL Loeb, NJ Izzo Jr, RM Johnson, JC Garrison, MJ Peach The American journal of cardiology 62 (11), 36-40, 1988 | 71 | 1988 |
Preclinical and clinical biomarker studies of CT1812: A novel approach to Alzheimer's disease modification NJ Izzo, CM Yuede, KM LaBarbera, CS Limegrover, C Rehak, R Yurko, ... Alzheimer's & Dementia 17 (8), 1365-1382, 2021 | 55 | 2021 |
Medicinal uses of hydrazones JIK Almstead, NJ Izzo, DR Jones, RM Kawamoto US Patent 6,660,737, 2003 | 53 | 2003 |