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Duo Xu
Duo Xu
Senior Computational Biologist @ Pathos
Verified email at pathos.com
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Cited by
Year
Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets
F Tang, D Xu, S Wang, CK Wong, A Martinez-Fundichely, CJ Lee, ...
Science 376 (6596), eabe1505, 2022
872022
Archaic Hominin Introgression in Africa Contributes to Functional Salivary MUC7 Genetic Variation
D Xu, P Pavlidis, RO Taskent, N Alachiotis, C Flanagan, M DeGiorgio, ...
Molecular Biology and Evolution 34 (10), 2704-2715, 2017
732017
Functional specialization of human salivary glands and origins of proteins intrinsic to human saliva
M Saitou, EA Gaylord, E Xu, AJ May, L Neznanova, S Nathan, A Grawe, ...
Cell reports 33 (7), 2020
642020
Atopic Dermatitis Susceptibility Variants in Filaggrin Hitchhike Hornerin Selective Sweep
M Eaaswarkhanth, D Xu, C Flanagan, M Rzhetskaya, MG Hayes, ...
Genome biology and evolution 8 (10), 3240-3255, 2016
442016
The psoriasis-associated deletion of late cornified envelope genes LCE3B and LCE3C has been maintained under balancing selection since Human Denisovan …
P Pajic, YL Lin, D Xu, O Gokcumen
BMC evolutionary biology 16, 1-7, 2016
362016
Recent evolution of the salivary mucin MUC7
D Xu, P Pavlidis, S Thamadilok, E Redwood, S Fox, R Blekhman, S Ruhl, ...
Scientific reports 6 (1), 31791, 2016
362016
Evolution and protein interactions of AP2 proteins in Brassicaceae: Evidence linking development and environmental responses
L Zeng, Y Yin, C You, Q Pan, D Xu, T Jin, B Zhang, H Ma
Journal of integrative plant biology 58 (6), 549-563, 2016
192016
VCFtoTree: a user-friendly tool to construct locus-specific alignments and phylogenies from thousands of anthropologically relevant genome sequences
D Xu, Y Jaber, P Pavlidis, O Gokcumen
BMC bioinformatics 18, 1-8, 2017
162017
Loss-of-function tolerance of enhancers in the human genome
D Xu, O Gokcumen, E Khurana
PLoS Genetics 16 (4), e1008663, 2020
132020
A candidate causal variant underlying both enhanced cognitive performance and increased risk of bipolar disorder
SQ Shen, JS Kim-Han, L Cheng, D Xu, O Gokcumen, AEO Hughes, ...
Biorxiv, 580258, 2019
122019
Discovery of novel therapeutic targets in cancer using patient-specific gene regulatory networks
AN Forbes
Weill Medical College of Cornell University, 2022
42022
Recapitulation of patient-specific 3D chromatin conformation using machine learning and validation of identified enhancer-gene targets
D Xu, AN Forbes, S Cohen, A Palladino, T Karadimitriou, E Khurana
bioRxiv, 2021.11. 16.468857, 2021
32021
Structural variants in ancient genomes
SD Resendez, JR Bradley, D Xu, O Gokcumen
Paleogenomics: Genome-scale analysis of ancient DNA, 375-391, 2019
32019
Recapitulation of patient-specific 3D chromatin conformation using machine learning
D Xu, AN Forbes, S Cohen, A Palladino, T Karadimitriou, E Khurana
Cell reports methods 3 (9), 2023
22023
Discovery of novel therapeutic targets using 3D chromatin conformation and patient-specific gene regulatory networks
AN Forbes, D Xu, S Cohen, A Palladino, P Pancholi, E Khurana
Cancer Research 83 (7_Supplement), 2034-2034, 2023
2023
Abstract NG10: Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets
F Tang, D Xu, S Wang, CK Wong, A Martinez-Fundichely, CJ Lee, ...
Cancer Research 83 (7_Supplement), NG10-NG10, 2023
2023
Abstract B026: Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets
F Tang, D Xu, S Wang, CK Wong, A Martinez-Fundichely, C Lee, S Cohen, ...
Cancer Research 82 (23_Supplement_2), B026-B026, 2022
2022
Identifying potential drug targets using patient-derived, tissue specific, gene regulatory networks
AN Forbes, D Xu, E Khurana
Cancer Research 81 (13_Supplement), 235-235, 2021
2021
Patient-specific enhancer-gene networks for hundreds of primary cancer samples
D Xu, AN Forbes, S Cohen, A Palladino, T Karadimitriou, E Khurana
Cancer Research 81 (13_Supplement), 2034-2034, 2021
2021
Assessing regulatory network rewiring in cancer patients using chromatin accessibility profiles
A Forbes, D Xu, EK Khurana
Cancer Research 80 (16_Supplement), 2478-2478, 2020
2020
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