Sifei Xing, Ph.D.
Sifei Xing, Ph.D.
Emory University School of Medicine
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An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients
CA Spina, J Anderson, NM Archin, A Bosque, J Chan, M Famiglietti, ...
PLoS pathogens 9 (12), e1003834, 2013
The HBV drug entecavir—effects on HIV-1 replication and resistance
MA McMahon, BL Jilek, TP Brennan, L Shen, Y Zhou, M Wind-Rotolo, ...
New England Journal of Medicine 356 (25), 2614-2621, 2007
Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation
HC Yang, S Xing, L Shan, K O’Connell, J Dinoso, A Shen, Y Zhou, ...
The Journal of clinical investigation 119 (11), 3473-3486, 2009
BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism
D Boehm, V Calvanese, RD Dar, S Xing, S Schroeder, L Martins, K Aull, ...
Cell cycle 12 (3), 452-462, 2013
Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation
S Xing, CK Bullen, NS Shroff, L Shan, HC Yang, JL Manucci, S Bhat, ...
Journal of virology 85 (12), 6060-6064, 2011
Transcriptional reprogramming during effector-to-memory transition renders CD4+ T cells permissive for latent HIV-1 infection
L Shan, K Deng, H Gao, S Xing, AA Capoferri, CM Durand, SA Rabi, ...
Immunity 47 (4), 766-775. e3, 2017
Targeting HIV latency: pharmacologic strategies toward eradication
S Xing, RF Siliciano
Drug discovery today 18 (11-12), 541-551, 2013
A critical subset model provides a conceptual basis for the high antiviral activity of major HIV drugs
L Shen, SA Rabi, AR Sedaghat, L Shan, J Lai, S Xing, RF Siliciano
Science translational medicine 3 (91), 91ra63-91ra63, 2011
Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation
S Xing, S Bhat, NS Shroff, H Zhang, JA Lopez, JB Margolick, JO Liu, ...
Journal of antimicrobial chemotherapy 67 (2), 398-403, 2012
Unique characteristics of histone deacetylase inhibitors in reactivation of latent HIV-1 in Bcl-2-transduced primary resting CD4+ T cells
L Shan, S Xing, HC Yang, H Zhang, JB Margolick, RF Siliciano
Journal of Antimicrobial Chemotherapy 69 (1), 28-33, 2014
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