JAK2V617F-mediated clonal hematopoiesis accelerates pathological remodeling in murine heart failure S Sano, Y Wang, Y Yura, M Sano, K Oshima, Y Yang, Y Katanasaka, ... JACC: Basic to Translational Science 4 (6), 684-697, 2019 | 142 | 2019 |
Loss of Ezh2 cooperates with Jak2V617F in the development of myelofibrosis in a mouse model of myeloproliferative neoplasm Y Yang, H Akada, D Nath, RE Hutchison, G Mohi Blood 127 (26), 3410-3423, 2016 | 94 | 2016 |
Genetic ablation of Pim1 or pharmacologic inhibition with TP-3654 ameliorates myelofibrosis in murine models A Dutta, D Nath, Y Yang, BT Le, MFU Rahman, P Faughnan, Z Wang, ... Leukemia 36 (3), 746-759, 2022 | 28 | 2022 |
Interleukin-1 contributes to clonal expansion and progression of bone marrow fibrosis in JAK2V617F-induced myeloproliferative neoplasm MFU Rahman, Y Yang, BT Le, A Dutta, J Posyniak, P Faughnan, ... Nature Communications 13 (1), 1-16, 2022 | 26 | 2022 |
U2af1 is required for survival and function of hematopoietic stem/progenitor cells A Dutta, Y Yang, BT Le, Y Zhang, O Abdel-Wahab, C Zang, G Mohi Leukemia 35 (8), 2382-2398, 2021 | 22 | 2021 |
The PIM kinase inhibitor TP-3654 in combination with ruxolitinib exhibits marked improvement of myelofibrosis in murine models D Nath, A Dutta, Y Yang, C Whatcott, SL Warner, G Mohi Blood 132 (Suppl 1), 54-54, 2018 | 15 | 2018 |
Deletion of Ptpn1 induces myeloproliferative neoplasm F Jobe, B Patel, T Kuzmanovic, H Makishima, Y Yang, B Przychodzen, ... Leukemia 31 (5), 1229, 2017 | 12 | 2017 |
CDK6 is a therapeutic target in myelofibrosis A Dutta, D Nath, Y Yang, BT Le, G Mohi Cancer Research 81 (16), 4332-4345, 2021 | 11 | 2021 |
The PIM kinase inhibitor TP-3654 demonstrates efficacy in a murine model of myelofibrosis A Dutta, D Nath, Y Yang, G Mohi Cancer Research 78 (13 Supplement), 1874-1874, 2018 | 3 | 2018 |
The NF-KB inhibitor DMAPT in combination with ruxolitinib displays efficacy in Jak2V617F knock-in mouse model of myeloproliferative neoplasms Y Yang, D Nath, A Dutta, PA Crooks, G Mohi Blood 132 (Supplement 1), 1783-1783, 2018 | 2 | 2018 |
IL-1 Signaling Promotes Clonal Expansion and Progression of Bone Marrow Fibrosis in JAK2V617F-Induced Myeloproliferative Neoplasm MFU Rahman, Y Yang, BT Le, A Dutta, P Faughnan, G Mohi Blood 138 (Supplement 1), 2540-2540, 2021 | 1 | 2021 |
The RNA Splicing Factor U2AF1 Controls Hematopoietic Stem Cell Survival and Function A Dutta, Y Yang, B Le, G Mohi BLOOD 136, 2020 | 1 | 2020 |
The CDK6 Inhibitor Palbociclib in Combination with Ruxolitinib Remarkably Improves Myelofibrosis in Murine Models G Mohi, A Dutta, D Nath, Y Yang Blood, The Journal of the American Society of Hematology 134 (Supplement_1 …, 2019 | 1 | 2019 |
Loss of EZH2 inhibits erythropoiesis and accelerates the development of myelofibrosis in Jak2V617F knock-in mice Y Yang, H Akada, D Nath, RE Hutchison, G Mohi Blood 124 (21), 159-159, 2014 | 1 | 2014 |
PTPN1 Deficiency Accelerates the Progression to Myelofibrosis in JAK2V617F-Driven Myeloproliferative Neoplasm BT Le, Y Yang, G Mohi Blood 140 (Supplement 1), 3855-3855, 2022 | | 2022 |
Inhibition of SHP2 Ameliorates JAK2V617F-Induced Myeloproliferative Neoplasms Y Yang, BT Le, A Dutta, G Mohi Blood 138 (Supplement 1), 1465-1465, 2021 | | 2021 |
Critical Requirement of U2AF1 in the Maintenance and Function of Hematopoietic Stem Cells A Dutta, Y Yang, B Le, G Mohi Blood, The Journal of the American Society of Hematology 134 (Supplement_1 …, 2019 | | 2019 |