SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas JA Müller, R Groß, C Conzelmann, J Krüger, U Merle, J Steinhart, T Weil, ... Nature metabolism 3 (2), 149-165, 2021 | 483 | 2021 |
Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling M Hohwieler, A Illing, PC Hermann, T Mayer, M Stockmann, L Perkhofer, ... Gut 66 (3), 473-486, 2017 | 222 | 2017 |
Single-cell-resolved differentiation of human induced pluripotent stem cells into pancreatic duct-like organoids on a microwell chip S Wiedenmann, M Breunig, J Merkle, C von Toerne, T Georgiev, ... Nature biomedical engineering 5 (8), 897-913, 2021 | 72 | 2021 |
Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells M Breunig, J Merkle, M Wagner, MK Melzer, TFE Barth, T Engleitner, ... Cell Stem Cell 28 (6), 1105-1124. e19, 2021 | 71 | 2021 |
Pancreatic cancer-derived organoids–a disease modeling tool to predict drug response PO Frappart, K Walter, J Gout, AK Beutel, M Morawe, F Arnold, M Breunig, ... United European Gastroenterology Journal 8 (5), 594-606, 2020 | 59 | 2020 |
The role of myosin 1c and myosin 1b in surfactant exocytosis N Kittelberger, M Breunig, R Martin, HJ Knölker, P Miklavc Journal of cell science 129 (8), 1685-1696, 2016 | 37 | 2016 |
Mutations and variants of ONECUT1 in diabetes A Philippi, S Heller, IG Costa, V Senée, M Breunig, Z Li, G Kwon, ... Nature Medicine 27 (11), 1928-1940, 2021 | 31 | 2021 |
Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation S Heller, Z Li, Q Lin, R Geusz, M Breunig, M Hohwieler, X Zhang, GG Nair, ... Communications biology 4 (1), 1298, 2021 | 21 | 2021 |
Differentiation of human pluripotent stem cells into pancreatic duct-like organoids M Breunig, J Merkle, MK Melzer, S Heller, T Seufferlein, M Meier, ... STAR protocols 2 (4), 100913, 2021 | 17 | 2021 |
CDKN2A-Mutated Pancreatic Ductal Organoids from Induced Pluripotent Stem Cells to Model a Cancer Predisposition Syndrome J Merkle, M Breunig, M Schmid, C Allgöwer, J Krüger, MK Melzer, S Bens, ... Cancers 13 (20), 5139, 2021 | 16 | 2021 |
High temporal resolution proteome and phosphoproteome profiling of stem cell-derived hepatocyte development J Krumm, K Sekine, P Samaras, A Brazovskaja, M Breunig, R Yasui, ... Cell reports 38 (13), 2022 | 10 | 2022 |
Reprogramming to pluripotency does not require transition through a primitive streak-like state S Raab, M Klingenstein, A Möller, A Illing, J Tosic, M Breunig, G Kuales, ... Scientific Reports 7 (1), 16543, 2017 | 10 | 2017 |
Organoids at the PUB: the porcine urinary bladder serves as a pancreatic niche for advanced cancer modeling MK Melzer, M Breunig, F Arnold, F Wezel, A Azoitei, E Roger, J Krüger, ... Advanced healthcare materials 11 (11), 2102345, 2022 | 9 | 2022 |
Functional genomic screening in human pluripotent stem cells reveals new roadblocks in early pancreatic endoderm formation J Krüger, M Breunig, LP Pasquini, M Morawe, A Groß, F Arnold, R Russell, ... Cells 11 (3), 582, 2022 | 4 | 2022 |
Protocol to use de-epithelialized porcine urinary bladder as a tissue scaffold for propagation of pancreatic cells MK Melzer, M Breunig, P Lopatta, M Hohwieler, S Merz, A Azoitei, ... STAR protocols 3 (4), 101869, 2022 | 2 | 2022 |
Pancreatic ductal organoids react KRAS dependent to the removal of tumor suppressive roadblocks L Perkhofer, M Engler, J Gout, F Arnold, M Morawe, M Breunig, ... Stem cells international 2019, 2019 | 2 | 2019 |