Extensive CRISPR RNA modification reveals chemical compatibility and structure-activity relationships for Cas9 biochemical activity D O’Reilly, ZJ Kartje, EA Ageely, E Malek-Adamian, M Habibian, ... Nucleic Acids Research 47 (2), 546-558, 2019 | 78 | 2019 |
Chimeric guides probe and enhance Cas9 biochemical activity ZJ Kartje, CL Barkau, KJ Rohilla, EA Ageely, KT Gagnon Biochemistry 57 (21), 3027-3031, 2018 | 48 | 2018 |
Rapid and adaptable measurement of protein thermal stability by differential scanning fluorimetry: updating a common biochemical laboratory experiment RJ Johnson, CJ Savas, Z Kartje, GC Hoops Journal of chemical education 91 (7), 1077-1080, 2014 | 39 | 2014 |
Revisiting T7 RNA polymerase transcription in vitro with the Broccoli RNA aptamer as a simplified real-time fluorescent reporter ZJ Kartje, HI Janis, S Mukhopadhyay, KT Gagnon Journal of Biological Chemistry 296, 2021 | 33 | 2021 |
Quadruplex-flanking stem structures modulate the stability and metal ion preferences of RNA mimics of GFP EA Ageely, ZJ Kartje, KJ Rohilla, CL Barkau, KT Gagnon ACS chemical biology 11 (9), 2398-2406, 2016 | 29 | 2016 |
A sensitive and robust enzyme kinetic experiment using microplates and fluorogenic ester substrates RJ Johnson, GC Hoops, CJ Savas, Z Kartje, LD Lavis Journal of chemical education 92 (2), 385-388, 2015 | 25 | 2015 |
Infrared spectroscopy reveals the preferred motif size and local disorder in parallel stranded DNA G‐quadruplexes DA Price, ZJ Kartje, JA Hughes, TD Hill, TM Loth, JK Watts, KT Gagnon, ... ChemBioChem 21 (19), 2792-2804, 2020 | 8 | 2020 |
G-rich motifs within phosphorothioate-based antisense oligonucleotides (ASOs) drive activation of FXN expression through indirect effects F Wang, E Calvo-Roitberg, JM Rembetsy-Brown, M Fang, J Sousa, ... Nucleic Acids Research 50 (22), 12657-12673, 2022 | 1 | 2022 |
Identifying non-productive splice sites JK Watts, K VALLA, ES KHOKHAR, Z KARTJE US Patent App. 17/781,569, 2023 | | 2023 |