| Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells S Cowley, H Paterson, P Kemp, CJ Marshall Cell 77 (6), 841-852, 1994 | 2527 | 1994 |
| Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27 NW Freshney, L Rawlinson, F Guesdon, E Jones, S Cowley, J Hsuan, ... Cell 78 (6), 1039-1049, 1994 | 1146 | 1994 |
| Microglia states and nomenclature: A field at its crossroads RC Paolicelli, A Sierra, B Stevens, ME Tremblay, A Aguzzi, B Ajami, I Amit, ... Neuron 110 (21), 3458-3483, 2022 | 928 | 2022 |
| Identification of the sites in MAP kinase kinase‐1 phosphorylated by p74raf‐1. DR Alessi, Y Saito, DG Campbell, P Cohen, G Sithanandam, U Rapp, ... The EMBO journal 13 (7), 1610-1619, 1994 | 822 | 1994 |
| A highly efficient human pluripotent stem cell microglia model displays a neuronal-co-culture-specific expression profile and inflammatory response W Haenseler, SN Sansom, J Buchrieser, SE Newey, CS Moore, ... Stem cell reports 8 (6), 1727-1742, 2017 | 515 | 2017 |
| ER stress and autophagic perturbations lead to elevated extracellular α-synuclein in GBA-N370S Parkinson's iPSC-derived dopamine neurons HJR Fernandes, EM Hartfield, HC Christian, E Emmanoulidou, Y Zheng, ... Stem cell reports 6 (3), 342-356, 2016 | 378 | 2016 |
| Efficient, long term production of monocyte-derived macrophages from human pluripotent stem cells under partly-defined and fully-defined conditions B Wilgenburg, C Browne, J Vowles, SA Cowley PloS one 8 (8), e71098, 2013 | 339 | 2013 |
| C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced … R Dafinca, J Scaber, N Ababneh, T Lalic, G Weir, H Christian, J Vowles, ... Stem cells 34 (8), 2063-2078, 2016 | 267 | 2016 |
| Homogeneous monocytes and macrophages from human embryonic stem cells following coculture-free differentiation in M-CSF and IL-3 KR Karlsson, S Cowley, FO Martinez, M Shaw, SL Minger, W James Experimental hematology 36 (9), 1167-1175, 2008 | 196 | 2008 |
| The mitogen-activated protein kinase kinase MEK1 stimulates a pattern of gene expression typical of the hypertrophic phenotype in rat ventricular cardiomyocytes J Gillespie-Brown, SJ Fuller, MA Bogoyevitch, S Cowley, PH Sugden Journal of Biological Chemistry 270 (47), 28092-28096, 1995 | 190 | 1995 |
| [29] Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf DR Alessi, P Cohen, A Ashworth, S Cowley, SJ Leevers, CJ Marshall Methods in enzymology 255, 279-290, 1995 | 190 | 1995 |
| LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages A Härtlova, S Herbst, J Peltier, A Rodgers, O Bilkei‐Gorzo, A Fearns, ... The EMBO journal 37 (12), e98694, 2018 | 178 | 2018 |
| Physiological characterisation of human iPS-derived dopaminergic neurons EM Hartfield, M Yamasaki-Mann, HJ Ribeiro Fernandes, J Vowles, ... PloS one 9 (2), e87388, 2014 | 177 | 2014 |
| Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells H Avraham, E Vannier, S Cowley, SX Jiang, S Chi, CA Dinarello, ... | 173 | 1992 |
| Transportin 3 promotes a nuclear maturation step required for efficient HIV-1 integration L Zhou, E Sokolskaja, C Jolly, W James, SA Cowley, A Fassati PLoS pathogens 7 (8), e1002194, 2011 | 171 | 2011 |
| Single-cell sequencing of iPSC-dopamine neurons reconstructs disease progression and identifies HDAC4 as a regulator of Parkinson cell phenotypes C Lang, KR Campbell, BJ Ryan, P Carling, M Attar, J Vowles, ... Cell stem cell 24 (1), 93-106. e6, 2019 | 169 | 2019 |
| A novel real time imaging platform to quantify macrophage phagocytosis TS Kapellos, L Taylor, H Lee, SA Cowley, WS James, AJ Iqbal, ... Biochemical pharmacology 116, 107-119, 2016 | 166 | 2016 |
| CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells R Flynn, A Grundmann, P Renz, W Hänseler, WS James, SA Cowley, ... Experimental hematology 43 (10), 838-848. e3, 2015 | 165 | 2015 |
| Alpha-synuclein induces the unfolded protein response in Parkinson’s disease SNCA triplication iPSC-derived neurons SM Heman-Ackah, R Manzano, JJM Hoozemans, W Scheper, R Flynn, ... Human molecular genetics 26 (22), 4441-4450, 2017 | 158 | 2017 |
| The roles of apoptotic pathways in the low recovery rate after cryopreservation of dissociated human embryonic stem cells X Xu, S Cowley, CJ Flaim, W James, L Seymour, Z Cui Biotechnology progress 26 (3), 827-837, 2010 | 158 | 2010 |
William JamesProfessor of Virology, University of OxfordVerified email at path.ox.ac.uk
