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Kergrohen Thomas
Kergrohen Thomas
Unknown affiliation
Verified email at gustaveroussy.fr
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Year
Histone H3 wild-type DIPG/DMG overexpressing EZHIP extend the spectrum diffuse midline gliomas with PRC2 inhibition beyond H3-K27M mutation
D Castel, T Kergrohen, A Tauziede-Espariat, A Mackay, S Ghermaoui, ...
Acta Neuropathologica 139, 1109-1113, 2020
1132020
Transcriptomic and epigenetic profiling of ‘diffuse midline gliomas, H3 K27M-mutant’discriminate two subgroups based on the type of histone H3 mutated and not supratentorial or …
D Castel, C Philippe, T Kergrohen, M Sill, J Merlevede, E Barret, S Puget, ...
Acta neuropathologica communications 6, 1-13, 2018
1042018
TP53 pathway alterations drive radioresistance in diffuse intrinsic pontine gliomas (DIPG)
C Werbrouck, CCS Evangelista, MJ Lobón-Iglesias, E Barret, G Le Teuff, ...
Clinical Cancer Research 25 (22), 6788-6800, 2019
772019
Both rare and common genetic variants contribute to autism in the Faroe Islands
CS Leblond, F Cliquet, C Carton, G Huguet, A Mathieu, T Kergrohen, ...
NPJ genomic medicine 4 (1), 1, 2019
602019
Antisense transcriptional interference mediates condition-specific gene repression in budding yeast
A Nevers, A Doyen, C Malabat, B Néron, T Kergrohen, A Jacquier, ...
Nucleic Acids Research 46 (12), 6009-6025, 2018
452018
Supratentorial non-RELA, ZFTA-fused ependymomas: a comprehensive phenotype genotype correlation highlighting the number of zinc fingers in ZFTA-NCOA1/2 fusions
A Tauziède-Espariat, A Siegfried, Y Nicaise, T Kergrohen, P Sievers, ...
Acta Neuropathologica Communications 9, 1-13, 2021
242021
The histomolecular criteria established for adult anaplastic pilocytic astrocytoma are not applicable to the pediatric population
A Gareton, A Tauziède-Espariat, V Dangouloff-Ros, A Roux, R Saffroy, ...
Acta Neuropathologica 139, 287-303, 2020
232020
A kinome-wide shRNA screen uncovers vaccinia-related kinase 3 (VRK3) as an essential gene for diffuse intrinsic pontine glioma survival
C Silva-Evangelista, E Barret, V Ménez, J Merlevede, T Kergrohen, ...
Oncogene 38 (38), 6479-6490, 2019
162019
Loss of Apc rapidly impairs DNA methylation programs and cell fate decisions in Lgr5+ intestinal stem cells
M Bruschi, L Garnier, E Cleroux, A Giordano, M Dumas, AF Bardet, ...
Cancer Research 80 (11), 2101-2113, 2020
152020
Pediatric spinal pilocytic astrocytomas form a distinct epigenetic subclass from pilocytic astrocytomas of other locations and diffuse leptomeningeal glioneuronal tumours
A Métais, Y Bouchoucha, T Kergrohen, V Dangouloff-Ros, X Maynadier, ...
Acta Neuropathologica 145 (1), 83-95, 2023
82023
Diffuse midline glioma invasion and metastasis rely on cell-autonomous signaling
M Bruschi, L Midjek, Y Ajlil, S Vairy, M Lancien, S Ghermaoui, ...
Neuro-oncology 26 (3), 553-568, 2024
22024
Biological medicines for diffuse intrinsic pontine glioma (DIPG) eradication (BIOMEDE): Final results of an international randomized phase II platform trial comparing 3 …
J Grill, G Le Teuff, P Varlet, DR Hargrave, K Nysom, K Blomgrenn, ...
Journal of Clinical Oncology 41 (16_suppl), 10003-10003, 2023
22023
Copy-number alterations reshape the classification of diffuse intrinsic pontine gliomas. First exome sequencing results of the BIOMEDE trial
T Kergrohen, D Castel, G Le Teuff, A Tauziède-Espariat, ...
medRxiv, 2021.04. 29.21256183, 2021
22021
A new subtype of diffuse midline glioma, H3 K27 and BRAF/FGFR1 co-altered: a clinico-radiological and histomolecular characterisation
L Auffret, Y Ajlil, A Tauziède-Espariat, T Kergrohen, C Puiseux, L Riffaud, ...
Acta Neuropathologica 147 (1), 2, 2024
12024
ROCK: digital normalization of whole genome sequencing data
V Legrand, T Kergrohen, N Joly, A Criscuolo
Journal of Open Source Software 7 (73), 3790, 2022
12022
PDTM-36. WHOLE EXOME SEQUENCING (WES) OF DIPG PATIENTS FROM THE BIOMEDE TRIAL REVEALS NEW PROGNOSTIC SUBGROUPS WITH SPECIFIC ONCOGENIC PROGRAMMES
MA Debily, T Kergrohen, P Varlet, G Le Teuff, K Nysom, K Blomgren, ...
Neuro-Oncology 21 (Suppl 6), vi195, 2019
12019
Clinico-radiological and histomolecular analyses identify of a new subtype of diffuse midline glioma, H3 K27 and BRAF/FGFR1 co-altered
L Auffret, Y Ajlil, A Tauziede-Espariat, T Kergrohen, C Puiseux, L Riffaud, ...
Cancer Research 84 (6_Supplement), 155-155, 2024
2024
Diffuse midline glioma invasion and metastasis rely on cell-autonomous signaling through a phenotypic switch controlled by BMP7
M Bruschi, L Midjek, Y Ajlil, S Vairy, M Lancien, S Ghermaoui, ...
Cancer Research 84 (6_Supplement), 154-154, 2024
2024
DIPG-38. PATIENT-DERIVED THREE-DIMENSIONAL AVATARS REVEAL CELL-AUTONOMOUS MECHANISMS DRIVING INVASION AND METASTATIC PROGRESSION IN DIFFUSE MIDLINE GLIOMAS
M Bruschi, L Midjek, Y Ajlil, S Vairy, M Lancien, S Ghermaoui, ...
Neuro-Oncology 25 (Suppl 1), i21, 2023
2023
HGG-17. SINGLE-CELL AND SPATIAL ANALYSES DECIPHER THE UNIQUE INVASIVE GROWTH PATTERN OF GLIOMATOSIS CEREBRI
S Crampsie, I Liu, LL Petrilli, A Mackay, G Spinozzi, Y Grabovska, ...
Neuro-Oncology 25 (Supplement_1), i42-i43, 2023
2023
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