Histone H3 wild-type DIPG/DMG overexpressing EZHIP extend the spectrum diffuse midline gliomas with PRC2 inhibition beyond H3-K27M mutation D Castel, T Kergrohen, A Tauziede-Espariat, A Mackay, S Ghermaoui, ... Acta Neuropathologica 139, 1109-1113, 2020 | 113 | 2020 |
Transcriptomic and epigenetic profiling of ‘diffuse midline gliomas, H3 K27M-mutant’discriminate two subgroups based on the type of histone H3 mutated and not supratentorial or … D Castel, C Philippe, T Kergrohen, M Sill, J Merlevede, E Barret, S Puget, ... Acta neuropathologica communications 6, 1-13, 2018 | 104 | 2018 |
TP53 pathway alterations drive radioresistance in diffuse intrinsic pontine gliomas (DIPG) C Werbrouck, CCS Evangelista, MJ Lobón-Iglesias, E Barret, G Le Teuff, ... Clinical Cancer Research 25 (22), 6788-6800, 2019 | 77 | 2019 |
Both rare and common genetic variants contribute to autism in the Faroe Islands CS Leblond, F Cliquet, C Carton, G Huguet, A Mathieu, T Kergrohen, ... NPJ genomic medicine 4 (1), 1, 2019 | 60 | 2019 |
Antisense transcriptional interference mediates condition-specific gene repression in budding yeast A Nevers, A Doyen, C Malabat, B Néron, T Kergrohen, A Jacquier, ... Nucleic Acids Research 46 (12), 6009-6025, 2018 | 45 | 2018 |
Supratentorial non-RELA, ZFTA-fused ependymomas: a comprehensive phenotype genotype correlation highlighting the number of zinc fingers in ZFTA-NCOA1/2 fusions A Tauziède-Espariat, A Siegfried, Y Nicaise, T Kergrohen, P Sievers, ... Acta Neuropathologica Communications 9, 1-13, 2021 | 24 | 2021 |
The histomolecular criteria established for adult anaplastic pilocytic astrocytoma are not applicable to the pediatric population A Gareton, A Tauziède-Espariat, V Dangouloff-Ros, A Roux, R Saffroy, ... Acta Neuropathologica 139, 287-303, 2020 | 23 | 2020 |
A kinome-wide shRNA screen uncovers vaccinia-related kinase 3 (VRK3) as an essential gene for diffuse intrinsic pontine glioma survival C Silva-Evangelista, E Barret, V Ménez, J Merlevede, T Kergrohen, ... Oncogene 38 (38), 6479-6490, 2019 | 16 | 2019 |
Loss of Apc rapidly impairs DNA methylation programs and cell fate decisions in Lgr5+ intestinal stem cells M Bruschi, L Garnier, E Cleroux, A Giordano, M Dumas, AF Bardet, ... Cancer Research 80 (11), 2101-2113, 2020 | 15 | 2020 |
Pediatric spinal pilocytic astrocytomas form a distinct epigenetic subclass from pilocytic astrocytomas of other locations and diffuse leptomeningeal glioneuronal tumours A Métais, Y Bouchoucha, T Kergrohen, V Dangouloff-Ros, X Maynadier, ... Acta Neuropathologica 145 (1), 83-95, 2023 | 8 | 2023 |
Diffuse midline glioma invasion and metastasis rely on cell-autonomous signaling M Bruschi, L Midjek, Y Ajlil, S Vairy, M Lancien, S Ghermaoui, ... Neuro-oncology 26 (3), 553-568, 2024 | 2 | 2024 |
Biological medicines for diffuse intrinsic pontine glioma (DIPG) eradication (BIOMEDE): Final results of an international randomized phase II platform trial comparing 3 … J Grill, G Le Teuff, P Varlet, DR Hargrave, K Nysom, K Blomgrenn, ... Journal of Clinical Oncology 41 (16_suppl), 10003-10003, 2023 | 2 | 2023 |
Copy-number alterations reshape the classification of diffuse intrinsic pontine gliomas. First exome sequencing results of the BIOMEDE trial T Kergrohen, D Castel, G Le Teuff, A Tauziède-Espariat, ... medRxiv, 2021.04. 29.21256183, 2021 | 2 | 2021 |
A new subtype of diffuse midline glioma, H3 K27 and BRAF/FGFR1 co-altered: a clinico-radiological and histomolecular characterisation L Auffret, Y Ajlil, A Tauziède-Espariat, T Kergrohen, C Puiseux, L Riffaud, ... Acta Neuropathologica 147 (1), 2, 2024 | 1 | 2024 |
ROCK: digital normalization of whole genome sequencing data V Legrand, T Kergrohen, N Joly, A Criscuolo Journal of Open Source Software 7 (73), 3790, 2022 | 1 | 2022 |
PDTM-36. WHOLE EXOME SEQUENCING (WES) OF DIPG PATIENTS FROM THE BIOMEDE TRIAL REVEALS NEW PROGNOSTIC SUBGROUPS WITH SPECIFIC ONCOGENIC PROGRAMMES MA Debily, T Kergrohen, P Varlet, G Le Teuff, K Nysom, K Blomgren, ... Neuro-Oncology 21 (Suppl 6), vi195, 2019 | 1 | 2019 |
Clinico-radiological and histomolecular analyses identify of a new subtype of diffuse midline glioma, H3 K27 and BRAF/FGFR1 co-altered L Auffret, Y Ajlil, A Tauziede-Espariat, T Kergrohen, C Puiseux, L Riffaud, ... Cancer Research 84 (6_Supplement), 155-155, 2024 | | 2024 |
Diffuse midline glioma invasion and metastasis rely on cell-autonomous signaling through a phenotypic switch controlled by BMP7 M Bruschi, L Midjek, Y Ajlil, S Vairy, M Lancien, S Ghermaoui, ... Cancer Research 84 (6_Supplement), 154-154, 2024 | | 2024 |
DIPG-38. PATIENT-DERIVED THREE-DIMENSIONAL AVATARS REVEAL CELL-AUTONOMOUS MECHANISMS DRIVING INVASION AND METASTATIC PROGRESSION IN DIFFUSE MIDLINE GLIOMAS M Bruschi, L Midjek, Y Ajlil, S Vairy, M Lancien, S Ghermaoui, ... Neuro-Oncology 25 (Suppl 1), i21, 2023 | | 2023 |
HGG-17. SINGLE-CELL AND SPATIAL ANALYSES DECIPHER THE UNIQUE INVASIVE GROWTH PATTERN OF GLIOMATOSIS CEREBRI S Crampsie, I Liu, LL Petrilli, A Mackay, G Spinozzi, Y Grabovska, ... Neuro-Oncology 25 (Supplement_1), i42-i43, 2023 | | 2023 |