| PTG-0861: A novel HDAC6-selective inhibitor as a therapeutic strategy in acute myeloid leukaemia JM Gawel, AE Shouksmith, YS Raouf, N Nawar, K Toutah, S Bukhari, ... European Journal of Medicinal Chemistry 201, 112411, 2020 | 36 | 2020 |
| Characterization of conformationally constrained benzanilide scaffolds for potent and selective HDAC8 targeting MM Hassan, J Israelian, N Nawar, G Ganda, P Manaswiyoungkul, ... Journal of Medicinal Chemistry 63 (15), 8634-8648, 2020 | 32 | 2020 |
| Recent advances in chemical biology using benzophenones and diazirines as radical precursors MM Hassan, OO Olaoye Molecules 25 (10), 2285, 2020 | 29 | 2020 |
| Development of HDAC inhibitors exhibiting therapeutic potential in T-cell prolymphocytic leukemia K Toutah, N Nawar, S Timonen, H Sorger, YS Raouf, S Bukhari, J von Jan, ... Journal of medicinal chemistry 64 (12), 8486-8509, 2021 | 28 | 2021 |
| Class I/IIb-selective HDAC inhibitor exhibits oral bioavailability and therapeutic efficacy in acute myeloid leukemia AE Shouksmith, JM Gawel, N Nawar, D Sina, YS Raouf, S Bukhari, L He, ... ACS Medicinal Chemistry Letters 11 (1), 56-64, 2019 | 24 | 2019 |
| Discovery of HDAC6-Selective Inhibitor NN-390 with in Vitro Efficacy in Group 3 Medulloblastoma N Nawar, S Bukhari, AA Adile, Y Suk, P Manaswiyoungkul, K Toutah, ... Journal of medicinal chemistry 65 (4), 3193-3217, 2022 | 18 | 2022 |
| Unique molecular interaction with the histone deacetylase 6 catalytic tunnel: Crystallographic and biological characterization of a model chemotype OO Olaoye, PR Watson, N Nawar, M Geletu, A Sedighi, S Bukhari, ... Journal of medicinal chemistry 64 (5), 2691-2704, 2021 | 18 | 2021 |
| Optimization of a high-throughput fluorescence polarization assay for STAT5B DNA binding domain-targeting inhibitors P Manaswiyoungkul, F Erdogan, OO Olaoye, AD Cabral, ED de Araujo, ... Journal of Pharmaceutical and Biomedical Analysis 184, 113182, 2020 | 7 | 2020 |
| Halogenated phenylsulfonamide hydroxamic acid compounds, compositions and uses thereof as selective hdac6 inhibitors PT Gunning, O Olaoye, K Toutah, AE Shouksmith, JM Shouksmith, ... US Patent App. 17/593,877, 2022 | | 2022 |
| Novel Molecular Templates Targeting Histone Deacetylase 6: Promising Strategy Towards Clinical Translation OO Olaoye University of Toronto (Canada), 2022 | | 2022 |
