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Zhen Lu
Zhen Lu
Ph.D student of cell biology, Tianjin Medical University, Postdoctoral of Biomedical Sciences
Verified email at upenn.edu
Title
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Cited by
Year
Dendritic cell-derived exosomes elicit tumor regression in autochthonous hepatocellular carcinoma mouse models
Z Lu, B Zuo, R Jing, X Gao, Q Rao, Z Liu, H Qi, H Guo, HF Yin
Journal of hepatology 67 (4), 739-748, 2017
3252017
Tumor‐derived exosomes elicit tumor suppression in murine hepatocellular carcinoma models and humans in vitro
Q Rao, B Zuo, Z Lu, X Gao, A You, C Wu, Z Du, HF Yin
Hepatology 64 (2), 456-472, 2016
2562016
Alarmin-painted exosomes elicit persistent antitumor immunity in large established tumors in mice
B Zuo, H Qi, Z Lu, L Chen, B Sun, R Yang, Y Zhang, Z Liu, X Gao, A You, ...
Nature communications 11 (1), 1790, 2020
1222020
A small-molecule SUMOylation inhibitor activates antitumor immune responses and potentiates immune therapies in preclinical models
ES Lightcap, P Yu, S Grossman, K Song, M Khattar, K Xega, X He, ...
Science translational medicine 13 (611), eaba7791, 2021
652021
Desmoplastic stroma restricts T cell extravasation and mediates immune exclusion and immunosuppression in solid tumors
Z Xiao, L Todd, L Huang, E Noguera-Ortega, Z Lu, L Huang, M Kopp, Y Li, ...
Nature Communications 14 (1), 5110, 2023
31*2023
Targeting PARP11 to avert immunosuppression and improve CAR T therapy in solid tumors
H Zhang, P Yu, VS Tomar, X Chen, MJ Atherton, Z Lu, HG Zhang, S Li, ...
Nature cancer 3 (7), 808-820, 2022
282022
ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes
Z Lu, N McBrearty, J Chen, VS Tomar, H Zhang, G De Rosa, A Tan, ...
Cell metabolism 34 (9), 1342-1358. e7, 2022
232022
Regulation of intercellular biomolecule transfer–driven tumor angiogenesis and responses to anticancer therapies
Z Lu, A Ortiz, II Verginadis, AR Peck, F Zahedi, C Cho, P Yu, RM DeRita, ...
The Journal of Clinical Investigation 131 (10), 2021
162021
Fluorescent peptide highlights micronodules in murine hepatocellular carcinoma models and humans in vitro
R Jing, X Zhou, J Zhao, Y Wei, B Zuo, A You, Q Rao, X Gao, R Yang, ...
Hepatology 68 (4), 1391-1411, 2018
162018
Tumor factors stimulate lysosomal degradation of tumor antigens and undermine their cross-presentation in lung cancer
Z Lu, J Chen, P Yu, MJ Atherton, J Gui, VS Tomar, JD Middleton, ...
Nature communications 13 (1), 6623, 2022
102022
Alarmin augments the antitumor immunity of lentiviral vaccine in ectopic, orthotopic and autochthonous hepatocellular carcinoma mice
Z Liu, Z Lu, R Jing, B Zuo, X Gao, G Han, H Qi, L Wu, Y Liu, H Yin
Theranostics 9 (14), 4006-4018, 2019
102019
Tumor-suppressive and immune-stimulating roles of cholesterol 25-hydroxylase in pancreatic cancer cells
N McBrearty, C Cho, J Chen, F Zahedi, AR Peck, E Radaelli, ...
Molecular Cancer Research 21 (3), 228-239, 2023
82023
Induction of the activating transcription factor-4 in the intratumoral CD8+ T cells sustains their viability and anti-tumor activities
Z Lu, EA Bae, II Verginadis, H Zhang, C Cho, N McBrearty, SS George, ...
Cancer Immunology, Immunotherapy 72 (4), 815-826, 2023
32023
Trogocytosis of cancer-associated fibroblasts promotes pancreatic cancer growth and immune suppression via phospholipid scramblase anoctamin 6 (ANO6).
C Ogier, AM Charles Solomon, Z Lu, L Recoules, A Klochkova, ...
bioRxiv, 2023.09. 15.557802, 2023
22023
ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes
Z Lu, N McBrearty, J Chen, VS Tomar, H Zhang, G De Rosa, A Tan, ...
Cell metabolism 36 (5), 1164-1167, 2024
2024
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