Dendritic cell-derived exosomes elicit tumor regression in autochthonous hepatocellular carcinoma mouse models Z Lu, B Zuo, R Jing, X Gao, Q Rao, Z Liu, H Qi, H Guo, HF Yin Journal of hepatology 67 (4), 739-748, 2017 | 325 | 2017 |
Tumor‐derived exosomes elicit tumor suppression in murine hepatocellular carcinoma models and humans in vitro Q Rao, B Zuo, Z Lu, X Gao, A You, C Wu, Z Du, HF Yin Hepatology 64 (2), 456-472, 2016 | 256 | 2016 |
Alarmin-painted exosomes elicit persistent antitumor immunity in large established tumors in mice B Zuo, H Qi, Z Lu, L Chen, B Sun, R Yang, Y Zhang, Z Liu, X Gao, A You, ... Nature communications 11 (1), 1790, 2020 | 122 | 2020 |
A small-molecule SUMOylation inhibitor activates antitumor immune responses and potentiates immune therapies in preclinical models ES Lightcap, P Yu, S Grossman, K Song, M Khattar, K Xega, X He, ... Science translational medicine 13 (611), eaba7791, 2021 | 65 | 2021 |
Desmoplastic stroma restricts T cell extravasation and mediates immune exclusion and immunosuppression in solid tumors Z Xiao, L Todd, L Huang, E Noguera-Ortega, Z Lu, L Huang, M Kopp, Y Li, ... Nature Communications 14 (1), 5110, 2023 | 31* | 2023 |
Targeting PARP11 to avert immunosuppression and improve CAR T therapy in solid tumors H Zhang, P Yu, VS Tomar, X Chen, MJ Atherton, Z Lu, HG Zhang, S Li, ... Nature cancer 3 (7), 808-820, 2022 | 28 | 2022 |
ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes Z Lu, N McBrearty, J Chen, VS Tomar, H Zhang, G De Rosa, A Tan, ... Cell metabolism 34 (9), 1342-1358. e7, 2022 | 23 | 2022 |
Regulation of intercellular biomolecule transfer–driven tumor angiogenesis and responses to anticancer therapies Z Lu, A Ortiz, II Verginadis, AR Peck, F Zahedi, C Cho, P Yu, RM DeRita, ... The Journal of Clinical Investigation 131 (10), 2021 | 16 | 2021 |
Fluorescent peptide highlights micronodules in murine hepatocellular carcinoma models and humans in vitro R Jing, X Zhou, J Zhao, Y Wei, B Zuo, A You, Q Rao, X Gao, R Yang, ... Hepatology 68 (4), 1391-1411, 2018 | 16 | 2018 |
Tumor factors stimulate lysosomal degradation of tumor antigens and undermine their cross-presentation in lung cancer Z Lu, J Chen, P Yu, MJ Atherton, J Gui, VS Tomar, JD Middleton, ... Nature communications 13 (1), 6623, 2022 | 10 | 2022 |
Alarmin augments the antitumor immunity of lentiviral vaccine in ectopic, orthotopic and autochthonous hepatocellular carcinoma mice Z Liu, Z Lu, R Jing, B Zuo, X Gao, G Han, H Qi, L Wu, Y Liu, H Yin Theranostics 9 (14), 4006-4018, 2019 | 10 | 2019 |
Tumor-suppressive and immune-stimulating roles of cholesterol 25-hydroxylase in pancreatic cancer cells N McBrearty, C Cho, J Chen, F Zahedi, AR Peck, E Radaelli, ... Molecular Cancer Research 21 (3), 228-239, 2023 | 8 | 2023 |
Induction of the activating transcription factor-4 in the intratumoral CD8+ T cells sustains their viability and anti-tumor activities Z Lu, EA Bae, II Verginadis, H Zhang, C Cho, N McBrearty, SS George, ... Cancer Immunology, Immunotherapy 72 (4), 815-826, 2023 | 3 | 2023 |
Trogocytosis of cancer-associated fibroblasts promotes pancreatic cancer growth and immune suppression via phospholipid scramblase anoctamin 6 (ANO6). C Ogier, AM Charles Solomon, Z Lu, L Recoules, A Klochkova, ... bioRxiv, 2023.09. 15.557802, 2023 | 2 | 2023 |
ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes Z Lu, N McBrearty, J Chen, VS Tomar, H Zhang, G De Rosa, A Tan, ... Cell metabolism 36 (5), 1164-1167, 2024 | | 2024 |