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Michael Karl Melzer
Michael Karl Melzer
Verified email at uni-ulm.de
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Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells
M Breunig, J Merkle, M Wagner, MK Melzer, TFE Barth, T Engleitner, ...
Cell Stem Cell 28 (6), 1105-1124. e19, 2021
782021
Oncolytic vesicular stomatitis virus as a viro-immunotherapy: defeating cancer with a “hammer” and “anvil”
MK Melzer, A Lopez-Martinez, J Altomonte
Biomedicines 5 (1), 8, 2017
762017
Enhanced safety and efficacy of oncolytic VSV therapy by combination with T cell receptor transgenic T cells as carriers
MK Melzer, L Zeitlinger, S Mall, K Steiger, RM Schmid, O Ebert, ...
Molecular Therapy-Oncolytics 12, 26-40, 2019
332019
An immunological glance on pancreatic ductal adenocarcinoma
MK Melzer, F Arnold, K Stifter, F Zengerling, N Azoitei, T Seufferlein, ...
International Journal of Molecular Sciences 21 (9), 3345, 2020
202020
Differentiation of human pluripotent stem cells into pancreatic duct-like organoids
M Breunig, J Merkle, MK Melzer, S Heller, T Seufferlein, M Meier, ...
STAR protocols 2 (4), 100913, 2021
172021
CDKN2A-Mutated Pancreatic Ductal Organoids from Induced Pluripotent Stem Cells to Model a Cancer Predisposition Syndrome
J Merkle, M Breunig, M Schmid, C Allgöwer, J Krüger, MK Melzer, S Bens, ...
Cancers 13 (20), 5139, 2021
162021
Organoids at the PUB: the porcine urinary bladder serves as a pancreatic niche for advanced cancer modeling
MK Melzer, M Breunig, F Arnold, F Wezel, A Azoitei, E Roger, J Krüger, ...
Advanced healthcare materials 11 (11), 2102345, 2022
92022
Single-cell profiling of GP2-enriched pancreatic progenitors to simultaneously create acinar, ductal, and endocrine organoids
S Merz, M Breuning, MK Melzer, S Heller, S Wiedenmann, T Seufferlein, ...
Theranostics 13 (6), 1949-1973, 2023
82023
Human pluripotent stem cells go diabetic: a glimpse on monogenic variants
S Heller, MK Melzer, N Azoitei, C Julier, A Kleger
Frontiers in Endocrinology 12, 648284, 2021
72021
The application of pancreatic cancer organoids for novel drug discovery
MK Melzer, Y Resheq, F Navaee, A Kleger
Expert Opinion on Drug Discovery 18 (4), 429-444, 2023
42023
State-matched organoid models to fight pancreatic cancer
MK Melzer, E Roger, A Kleger
Trends in Cancer 8 (6), 445-447, 2022
32022
DNA methylation‐associated allelic inactivation regulates Keratin 19 gene expression during pancreatic development and carcinogenesis
J Krüger, A Fischer, M Breunig, C Allgöwer, L Schulte, J Merkle, ...
The Journal of Pathology 261 (2), 139-155, 2023
22023
Protocol to use de-epithelialized porcine urinary bladder as a tissue scaffold for propagation of pancreatic cells
MK Melzer, M Breunig, P Lopatta, M Hohwieler, S Merz, A Azoitei, ...
STAR protocols 3 (4), 101869, 2022
22022
TBX3 is dynamically expressed in pancreatic organogenesis and fine-tunes regeneration
MK Melzer, S Schirge, J Gout, F Arnold, D Srinivasan, I Burtscher, ...
BMC biology 21 (1), 55, 2023
12023
Organoids as a milestone on the way to personalized treatment of urothelial carcinoma: a systematic review
MK Melzer, V Zehe, F Zengerling, F Wezel, C Günes, P Maisch, C Bolenz
Urologie (Heidelberg, Germany) 61 (7), 745-752, 2022
12022
Abstract B14: TCR transgenic T cells improve the anticancer potential of oncolytic vesicular stomatitis virus as cell carriers and as synergistic therapeutics
MK Melzer, L Zeitlinger, S Mall, K Steiger, A Krackhardt, O Ebert, ...
Cancer Immunology Research 6 (9_Supplement), B14-B14, 2018
12018
TCR transgenic T cells improve the anticancer potential of oncolytic vesicular stomatitis virus as cell carriers and as synergistic therapeutics
MK Melzer, L Zeitlinger, S Mall, K Steiger, A Krackhardt, O Ebert, ...
12018
Abstract A061: DKK3 in pancreatic cancer–Elucidating the roles of a double-edged sword
D Srinivasan, F Arnold, E Roger, A Härle, MK Melzer, C Allgöwer, ...
Cancer Research 84 (17_Supplement_2), A061-A061, 2024
2024
Assessment of cancer cell invasion and high-throughput screenings in a novel ex vivo murine bladder tissue model
C Gunes, J Liu, W Jiang, X Wang, A Azoitei, M Melzer, F Wezel, C Bolenz
European Urology 85, S1895, 2024
2024
Prospective standardization of organoid-based pharmacotyping in urothelial carcinoma
MK Melzer, Y Ma, J Lindenmayer, F Zengerling, F Wezel, C Günes, ...
European Urology 85, S1911, 2024
2024
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