Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells M Breunig, J Merkle, M Wagner, MK Melzer, TFE Barth, T Engleitner, ... Cell Stem Cell 28 (6), 1105-1124. e19, 2021 | 78 | 2021 |
Oncolytic vesicular stomatitis virus as a viro-immunotherapy: defeating cancer with a “hammer” and “anvil” MK Melzer, A Lopez-Martinez, J Altomonte Biomedicines 5 (1), 8, 2017 | 76 | 2017 |
Enhanced safety and efficacy of oncolytic VSV therapy by combination with T cell receptor transgenic T cells as carriers MK Melzer, L Zeitlinger, S Mall, K Steiger, RM Schmid, O Ebert, ... Molecular Therapy-Oncolytics 12, 26-40, 2019 | 33 | 2019 |
An immunological glance on pancreatic ductal adenocarcinoma MK Melzer, F Arnold, K Stifter, F Zengerling, N Azoitei, T Seufferlein, ... International Journal of Molecular Sciences 21 (9), 3345, 2020 | 20 | 2020 |
Differentiation of human pluripotent stem cells into pancreatic duct-like organoids M Breunig, J Merkle, MK Melzer, S Heller, T Seufferlein, M Meier, ... STAR protocols 2 (4), 100913, 2021 | 17 | 2021 |
CDKN2A-Mutated Pancreatic Ductal Organoids from Induced Pluripotent Stem Cells to Model a Cancer Predisposition Syndrome J Merkle, M Breunig, M Schmid, C Allgöwer, J Krüger, MK Melzer, S Bens, ... Cancers 13 (20), 5139, 2021 | 16 | 2021 |
Organoids at the PUB: the porcine urinary bladder serves as a pancreatic niche for advanced cancer modeling MK Melzer, M Breunig, F Arnold, F Wezel, A Azoitei, E Roger, J Krüger, ... Advanced healthcare materials 11 (11), 2102345, 2022 | 9 | 2022 |
Single-cell profiling of GP2-enriched pancreatic progenitors to simultaneously create acinar, ductal, and endocrine organoids S Merz, M Breuning, MK Melzer, S Heller, S Wiedenmann, T Seufferlein, ... Theranostics 13 (6), 1949-1973, 2023 | 8 | 2023 |
Human pluripotent stem cells go diabetic: a glimpse on monogenic variants S Heller, MK Melzer, N Azoitei, C Julier, A Kleger Frontiers in Endocrinology 12, 648284, 2021 | 7 | 2021 |
The application of pancreatic cancer organoids for novel drug discovery MK Melzer, Y Resheq, F Navaee, A Kleger Expert Opinion on Drug Discovery 18 (4), 429-444, 2023 | 4 | 2023 |
State-matched organoid models to fight pancreatic cancer MK Melzer, E Roger, A Kleger Trends in Cancer 8 (6), 445-447, 2022 | 3 | 2022 |
DNA methylation‐associated allelic inactivation regulates Keratin 19 gene expression during pancreatic development and carcinogenesis J Krüger, A Fischer, M Breunig, C Allgöwer, L Schulte, J Merkle, ... The Journal of Pathology 261 (2), 139-155, 2023 | 2 | 2023 |
Protocol to use de-epithelialized porcine urinary bladder as a tissue scaffold for propagation of pancreatic cells MK Melzer, M Breunig, P Lopatta, M Hohwieler, S Merz, A Azoitei, ... STAR protocols 3 (4), 101869, 2022 | 2 | 2022 |
TBX3 is dynamically expressed in pancreatic organogenesis and fine-tunes regeneration MK Melzer, S Schirge, J Gout, F Arnold, D Srinivasan, I Burtscher, ... BMC biology 21 (1), 55, 2023 | 1 | 2023 |
Organoids as a milestone on the way to personalized treatment of urothelial carcinoma: a systematic review MK Melzer, V Zehe, F Zengerling, F Wezel, C Günes, P Maisch, C Bolenz Urologie (Heidelberg, Germany) 61 (7), 745-752, 2022 | 1 | 2022 |
Abstract B14: TCR transgenic T cells improve the anticancer potential of oncolytic vesicular stomatitis virus as cell carriers and as synergistic therapeutics MK Melzer, L Zeitlinger, S Mall, K Steiger, A Krackhardt, O Ebert, ... Cancer Immunology Research 6 (9_Supplement), B14-B14, 2018 | 1 | 2018 |
TCR transgenic T cells improve the anticancer potential of oncolytic vesicular stomatitis virus as cell carriers and as synergistic therapeutics MK Melzer, L Zeitlinger, S Mall, K Steiger, A Krackhardt, O Ebert, ... | 1 | 2018 |
Abstract A061: DKK3 in pancreatic cancer–Elucidating the roles of a double-edged sword D Srinivasan, F Arnold, E Roger, A Härle, MK Melzer, C Allgöwer, ... Cancer Research 84 (17_Supplement_2), A061-A061, 2024 | | 2024 |
Assessment of cancer cell invasion and high-throughput screenings in a novel ex vivo murine bladder tissue model C Gunes, J Liu, W Jiang, X Wang, A Azoitei, M Melzer, F Wezel, C Bolenz European Urology 85, S1895, 2024 | | 2024 |
Prospective standardization of organoid-based pharmacotyping in urothelial carcinoma MK Melzer, Y Ma, J Lindenmayer, F Zengerling, F Wezel, C Günes, ... European Urology 85, S1911, 2024 | | 2024 |