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| Curling of flap tips in HIV-1 protease as a mechanism for substrate entry and tolerance of drug resistance WRP Scott, CA Schiffer Structure 8 (12), 1259-1265, 2000 | 246 | 2000 |
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| Replacement of the P1 amino acid of human immunodeficiency virus type 1 Gag processing sites can inhibit or enhance the rate of cleavage by the viral protease SC Pettit, GJ Henderson, CA Schiffer, R Swanstrom Journal of virology 76 (20), 10226-10233, 2002 | 142 | 2002 |
| Methylcytosine and normal cytosine deamination by the foreign DNA restriction enzyme APOBEC3A MA Carpenter, M Li, A Rathore, L Lackey, EK Law, AM Land, B Leonard, ... Journal of Biological Chemistry 287 (41), 34801-34808, 2012 | 137 | 2012 |
| HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants MD Altman, A Ali, GSK Kumar Reddy, MNL Nalam, SG Anjum, H Cao, ... Journal of the American Chemical Society 130 (19), 6099-6113, 2008 | 135 | 2008 |
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| Evaluating the substrate-envelope hypothesis: structural analysis of novel HIV-1 protease inhibitors designed to be robust against drug resistance MNL Nalam, A Ali, MD Altman, GSKK Reddy, S Chellappan, V Kairys, ... Journal of virology 84 (10), 5368-5378, 2010 | 125 | 2010 |
Aysegul OzenScorpion TherapeuticsVerified email at scorpiontx.com
