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Brenda D. Moore
Brenda D. Moore
Verified email at emory.edu
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Cited by
Cited by
Year
Substrate-targeting γ-secretase modulators
TL Kukar, TB Ladd, MA Bann, PC Fraering, R Narlawar, GM Maharvi, ...
Nature 453 (7197), 925-929, 2008
3772008
IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior
P Chakrabarty, A Li, C Ceballos-Diaz, JA Eddy, CC Funk, B Moore, ...
Neuron 85 (3), 519-533, 2015
3762015
Amyloid-β (1− 42) rapidly forms protofibrils and oligomers by distinct pathways in low concentrations of sodium dodecylsulfate
V Rangachari, BD Moore, DK Reed, LK Sonoda, AW Bridges, E Conboy, ...
Biochemistry 46 (43), 12451-12462, 2007
2092007
Divergent effects of the H50Q and G51D SNCA mutations on the aggregation of α‐synuclein
NJ Rutherford, BD Moore, TE Golde, BI Giasson
Journal of neurochemistry 131 (6), 859-867, 2014
1392014
BRI2 (ITM2b) inhibits Aβ deposition in vivo
J Kim, VM Miller, Y Levites, KJ West, CW Zwizinski, BD Moore, ...
Journal of Neuroscience 28 (23), 6030-6036, 2008
1372008
Overlapping profiles of Aβ peptides in the Alzheimer's disease and pathological aging brains
BD Moore, P Chakrabarty, Y Levites, TL Kukar, AM Baine, T Moroni, ...
Alzheimer's research & therapy 4, 1-15, 2012
1232012
Secondary structure and interfacial aggregation of amyloid-β (1− 40) on sodium dodecyl sulfate micelles
V Rangachari, DK Reed, BD Moore, TL Rosenberry
Biochemistry 45 (28), 8639-8648, 2006
1122006
Organotypic brain slice cultures to model neurodegenerative proteinopathies
CL Croft, HS Futch, BD Moore, TE Golde
Molecular Neurodegeneration 14, 1-11, 2019
922019
Lysine 624 of the amyloid precursor protein (APP) is a critical determinant of amyloid β peptide length: Support for a sequential model of γ-secretase intramembrane proteolysis …
TL Kukar, TB Ladd, P Robertson, SA Pintchovski, B Moore, MA Bann, ...
Journal of Biological Chemistry 286 (46), 39804-39812, 2011
822011
Short Aβ peptides attenuate Aβ42 toxicity in vivo
BD Moore, J Martin, L de Mena, J Sanchez, PE Cruz, C Ceballos-Diaz, ...
Journal of Experimental Medicine 215 (1), 283-301, 2018
712018
Biophysical analyses of synthetic Amyloid-β (1− 42) aggregates before and after covalent cross-linking. Implications for deducing the structure of endogenous Amyloid-β oligomers
BD Moore, V Rangachari, WM Tay, NM Milkovic, TL Rosenberry
Biochemistry 48 (49), 11796-11806, 2009
672009
TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer’s disease
P Chakrabarty, A Li, TB Ladd, MR Strickland, EJ Koller, JD Burgess, ...
Journal of Experimental Medicine 215 (9), 2247-2264, 2018
552018
Reversible pathologic and cognitive phenotypes in an inducible model of Alzheimer-amyloidosis
T Melnikova, S Fromholt, HS Kim, D Lee, G Xu, A Price, BD Moore, ...
Journal of Neuroscience 33 (9), 3765-3779, 2013
552013
Cytosolic proteins lose solubility as amyloid deposits in a transgenic mouse model of Alzheimer-type amyloidosis
G Xu, SM Stevens Jr, BD Moore, S McClung, DR Borchelt
Human molecular genetics 22 (14), 2765-2774, 2013
532013
A novel panel of α-synuclein antibodies reveal distinctive staining profiles in synucleinopathies
JKS Dhillon, C Riffe, BD Moore, Y Ran, P Chakrabarty, TE Golde, ...
PloS one 12 (9), e0184731, 2017
502017
Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau
KH Strang, MS Goodwin, C Riffe, BD Moore, P Chakrabarty, Y Levites, ...
Acta neuropathologica communications 5, 1-11, 2017
482017
Steroids as γ-secretase modulators
JI Jung, TB Ladd, T Kukar, AR Price, BD Moore, EH Koo, TE Golde, ...
The FASEB Journal 27 (9), 3775, 2013
442013
Retention in endoplasmic reticulum 1 (RER1) modulates amyloid-β (Aβ) production by altering trafficking of γ-secretase and amyloid precursor protein (APP)
HJ Park, D Shabashvili, MD Nekorchuk, E Shyqyriu, JI Jung, TB Ladd, ...
Journal of Biological Chemistry 287 (48), 40629-40640, 2012
412012
Rationally designed dehydroalanine (ΔAla)‐containing peptides inhibit amyloid‐β (Aβ) peptide aggregation
V Rangachari, ZS Davey, B Healy, BD Moore, LK Sonoda, B Cusack, ...
Biopolymers: Original Research on Biomolecules 91 (6), 456-465, 2009
392009
Structural insights and functional implications of choline acetyltransferase
L Govindasamy, B Pedersen, W Lian, T Kukar, Y Gu, S Jin, ...
Journal of structural biology 148 (2), 226-235, 2004
382004
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