Daniel Nyhan
Daniel Nyhan
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Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels
DE Berkowitz, R White, D Li, KM Minhas, A Cernetich, S Kim, S Burke, ...
Circulation 108 (16), 2000-2006, 2003
Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats
JH Kim, LJ Bugaj, YJ Oh, TJ Bivalacqua, S Ryoo, KG Soucy, L Santhanam, ...
Journal of applied physiology 107 (4), 1249-1257, 2009
Endothelial arginase II: a novel target for the treatment of atherosclerosis
S Ryoo, G Gupta, A Benjo, HK Lim, A Camara, G Sikka, HK Lim, J Sohi, ...
Circulation research 102 (8), 923-932, 2008
Association of protamine IgE and IgG antibodies with life-threatening reactions to intravenous protamine
ME Weiss, D Nyhan, Z Peng, JC Horrow, E Lowenstein, C Hirshman, ...
New England Journal of Medicine 320 (14), 886-892, 1989
Vascular stiffness and increased pulse pressure in the aging cardiovascular system
J Steppan, V Barodka, DE Berkowitz, D Nyhan
Cardiology research and practice 2011, 2011
Inducible NO Synthase–Dependent S-Nitrosylation and Activation of Arginase1 Contribute to Age-Related Endothelial Dysfunction
L Santhanam, HK Lim, HK Lim, V Miriel, T Brown, M Patel, S Balanson, ...
Circulation research 101 (7), 692-702, 2007
Knockdown of arginase I restores NO signaling in the vasculature of old rats
AR White, S Ryoo, D Li, HC Champion, J Steppan, D Wang, D Nyhan, ...
Hypertension 47 (2), 245-251, 2006
Oxidized low-density lipoprotein–dependent endothelial arginase II activation contributes to impaired nitric oxide signaling
S Ryoo, CA Lemmon, KG Soucy, G Gupta, AR White, D Nyhan, ...
Circulation research 99 (9), 951-960, 2006
Arginase and vascular aging
L Santhanam, DW Christianson, D Nyhan, DE Berkowitz
Journal of applied physiology 105 (5), 1632-1642, 2008
Reduction of obesity, as induced by leptin, reverses endothelial dysfunction in obese (Lepob ) mice
B Winters, Z Mo, E Brooks-Asplund, S Kim, A Shoukas, D Li, D Nyhan, ...
Journal of Applied Physiology 89 (6), 2382-2390, 2000
Impaired shear stress-induced nitric oxide production through decreased NOS phosphorylation contributes to age-related vascular stiffness
KG Soucy, S Ryoo, A Benjo, HK Lim, G Gupta, JS Sohi, J Elser, MA Aon, ...
Journal of Applied Physiology 101 (6), 1751-1759, 2006
Distribution of pulmonary ventilation using Xe-enhanced computed tomography in prone and supine dogs
C Marcucci, D Nyhan, BA Simon
Journal of applied physiology 90 (2), 421-430, 2001
Decreased S-Nitrosylation of Tissue Transglutaminase Contributes to Age-Related Increases in Vascular Stiffness
L Santhanam, EC Tuday, AK Webb, P Dowzicky, JH Kim, YJ Oh, G Sikka, ...
Circulation research 107 (1), 117-125, 2010
Implications of vascular aging
VM Barodka, BL Joshi, DE Berkowitz, CW Hogue Jr, D Nyhan
Anesthesia and analgesia 112 (5), 1048, 2011
Hypertrophic cardiomyopathy: a review
N Hensley, J Dietrich, D Nyhan, N Mitter, MS Yee, MB Brady
Anesthesia & Analgesia 120 (3), 554-569, 2015
Melanopsin mediates light-dependent relaxation in blood vessels
G Sikka, GP Hussmann, D Pandey, S Cao, D Hori, JT Park, J Steppan, ...
Proceedings of the National Academy of Sciences 111 (50), 17977-17982, 2014
N omega-nitro-L-arginine and pulmonary vascular pressure-flow relationship in conscious dogs
K Nishiwaki, DP Nyhan, P Rock, PM Desai, WP Peterson, CG Pribble, ...
American Journal of Physiology-Heart and Circulatory Physiology 262 (5 …, 1992
Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism
J Steppan, S Ryoo, KH Schuleri, C Gregg, RK Hasan, AR White, LJ Bugaj, ...
Proceedings of the National Academy of Sciences 103 (12), 4759-4764, 2006
Development of novel arginase inhibitors for therapy of endothelial dysfunction
J Steppan, D Nyhan, DE Berkowitz
Frontiers in immunology 4, 278, 2013
Exercise, vascular stiffness, and tissue transglutaminase
J Steppan, G Sikka, S Jandu, V Barodka, MK Halushka, NA Flavahan, ...
Journal of the American Heart Association 3 (2), e000599, 2014
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