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Nilesh Deshpande
Nilesh Deshpande
Postdoctoral Researcher at University of Massachusetts, Amherst, MA, USA
Verified email at umass.edu
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Cited by
Cited by
Year
Cisplatin-stitched polysaccharide vesicles for synergistic cancer therapy of triple antagonistic drugs
NU Deshpande, M Jayakannan
Biomacromolecules 18 (1), 113-126, 2017
512017
Targeting PI3K pathway in pancreatic ductal adenocarcinoma: rationale and progress
S Mehra, N Deshpande, N Nagathihalli
Cancers 13 (17), 4434, 2021
492021
Biotin-tagged polysaccharide vesicular nanocarriers for receptor-mediated anticancer drug delivery in cancer cells
NU Deshpande, M Jayakannan
Biomacromolecules 19 (8), 3572-3585, 2018
492018
Cell-autonomous Cxcl1 sustains tolerogenic circuitries and stromal inflammation via neutrophil-derived TNF in pancreatic cancer
A Bianchi, I De Castro Silva, NU Deshpande, S Singh, S Mehra, ...
Cancer discovery 13 (6), 1428-1453, 2023
322023
Real-time drug release analysis of enzyme and pH responsive polysaccharide nanovesicles
PS Pramod, NU Deshpande, M Jayakannan
The Journal of Physical Chemistry B 119 (33), 10511-10523, 2015
272015
An AIE-driven fluorescent polysaccharide polymersome as an enzyme-responsive FRET nanoprobe to study the real-time delivery aspects in live cells
NU Deshpande, M Virmani, M Jayakannan
Polymer Chemistry 12 (10), 1549-1561, 2021
242021
Distinct mechanisms of innate and adaptive immune regulation underlie poor oncologic outcomes associated with KRAS-TP53 co-alteration in pancreatic cancer
J Datta, A Bianchi, I De Castro Silva, NU Deshpande, LL Cao, S Mehra, ...
Oncogene 41 (28), 3640-3654, 2022
202022
Engineered multifunctional nano‐and biological materials for cancer immunotherapy
A Brouillard, N Deshpande, AA Kulkarni
Advanced Healthcare Materials 10 (6), 2001680, 2021
182021
Neutrophil-mediated fibroblast-tumor cell il-6/stat-3 signaling underlies the association between neutrophil-to-lymphocyte ratio dynamics and chemotherapy response in localized …
I de Castro Silva, A Bianchi, NU Deshpande, P Sharma, S Mehra, ...
Elife 11, e78921, 2022
172022
Polymer nanovesicle-mediated delivery of MLN8237 preferentially inhibits Aurora kinase a to target RalA and anchorage-independent growth in breast cancer cells
S Inchanalkar, NU Deshpande, V Kasherwal, M Jayakannan, ...
Molecular Pharmaceutics 15 (8), 3046-3059, 2018
112018
Supramolecular polysaccharide nanotheranostics that inhibit cancer cells growth and monitor targeted therapy response
N Deshpande, A Ramesh, D Nandi, A Nguyen, A Brouillard, A Kulkarni
Nanotheranostics 4 (3), 156, 2020
82020
Self-reporting polysaccharide polymersome for doxorubicin and cisplatin delivery to live cancer cells
M Virmani, NU Deshpande, S Pathan, M Jayakannan
ACS Polymers Au 2 (3), 181-193, 2021
62021
Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers
AR Dosch, WK Chatila, Y Ban, A Bianchi, NU Deshpande, IDC Silva, ...
Oncotarget 12 (20), 2104, 2021
52021
Activatable Nanoreporters for Real‐Time Tracking of Macrophage Phenotypic States Associated with Disease Progression
A Ramesh, N Deshpande, V Malik, A Nguyen, M Malhotra, M Debnath, ...
Small 19 (41), 2300978, 2023
12023
Abstract C021: Granulocytic MDSC-derived NLRP3 inflammasome activation is a novel regulator of inflammatory CAF skewness in pancreatic cancer
K Rajkumar, NU Deshpande, I de Castro Silva, A Bianchi, I Ogobuiro, ...
Cancer Research 84 (2_Supplement), C021-C021, 2024
2024
Granulocytic MDSC-derived NLRP3 inflammasome activation is a novel regulator of inflammatory CAF skewness in pancreatic cancer
K Rajkumar, NU Deshpande, IC Silva, A Bianchi, I Ogobuiro, H Amirian, ...
CANCER RESEARCH 84 (2), 2024
2024
Cell-specific nanoengineering strategy disrupts tolerogenic signaling from myeloid-derived suppressor cells to invigorate antitumor immunity in pancreatic cancer
NU Deshpande, A Bianchi, H Amirian, I De Castro Silva, CI Rafie, ...
bioRxiv, 2024.05. 25.594901, 2024
2024
KRAS-TP53 cooperativity regulates Cxcl1 to sustain tumor-permissive circuitry via granulocyte-derived CXCR2-TNF signaling in pancreatic cancer.
A Bianchi, IDC Silva, NU Deshpande, S Mehra, VT Garrido, S Singh, ...
CANCER RESEARCH 82 (22), 132-133, 2022
2022
Targeting granulocytic MDSC-derived inflammasome activation to overcome stromal inflammation in pancreatic cancer.
N Deshpande, A Bianchi, IDC Silva, V Garrido, S Mehra, S Singh, ...
CANCER RESEARCH 82 (22), 130-131, 2022
2022
Targeting tumor intrinsic p38 MAPK signaling to block IL-1a-mediated inflammatory tumor-stromal crosstalk in pancreatic cancer.
SP Singh, AR Dosch, S Mehra, IC Silva, A Bianchi, V Tonin-Garrido, ...
CANCER RESEARCH 82 (22), 151-152, 2022
2022
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