EGFR inhibitors and apoptotic inducers: Design, synthesis, anticancer activity and docking studies of novel xanthine derivatives carrying chalcone moiety as hybrid molecules HA Abou-Zied, BGM Youssif, MFA Mohamed, AM Hayallah, M Abdel-Aziz Bioorganic chemistry 89, 102997, 2019 | 117 | 2019 |
Discovery of new cyanopyridine/chalcone hybrids as dual inhibitors of EGFR/BRAFV600E with promising antiproliferative properties HA Abou‐Zied, EAM Beshr, HAM Gomaa, YA Mostafa, BGM Youssif, ... Archiv der Pharmazie 356 (4), 2200464, 2023 | 10 | 2023 |
Design, Synthesis, Antiproliferative Actions, and DFT Studies of New Bis–Pyrazoline Derivatives as Dual EGFR/BRAFV600E Inhibitors LH Al-Wahaibi, HA Abou-Zied, EAM Beshr, BGM Youssif, AM Hayallah, ... International Journal of Molecular Sciences 24 (10), 9104, 2023 | 6 | 2023 |
Emerging Insights into Pyrazoline Motifs: A Comprehensive Exploration of Biological Mechanisms and Prospects for Future Advancements HA Abou-Zied, EAM Beshr, AM Hayallah, M Abdel-Aziz Journal of Molecular Structure, 136807, 2023 | 2 | 2023 |
Design, Synthesis, and Biological Evaluation of Novel 3-Cyanopyridone/Pyrazoline Hybrids as Potential Apoptotic Antiproliferative Agents Targeting EGFR/BRAFV600E Inhibitory … LH Al-Wahaibi, HA Abou-Zied, M Hisham, EAM Beshr, BGM Youssif, ... Molecules 28 (18), 6586, 2023 | 1 | 2023 |
Design and synthesis of new quinoline-ester/-amide derivatives as potent antiproliferative agent targeting EGFR and BRAFV600E kinases AM Mohassab, HA Hassan, HA Abou-Zied, M Fujita, M Otsuka, ... Journal of Molecular Structure 1297, 136953, 2024 | | 2024 |
New pyrrolidine‐carboxamide derivatives as dual antiproliferative EGFR/CDK2 inhibitors FOA Frejat, B Zhao, N Furaijit, L Wang, HA Abou‐Zied, HM Fathy, ... Chemical Biology & Drug Design 103 (1), e14422, 2024 | | 2024 |
Quinazolin-4-one/3-cyanopyridin-2-one Hybrids as Dual Inhibitors of EGFR and BRAFV600E: Design, Synthesis, and Antiproliferative Activity LH Al-Wahaibi, M Hisham, HA Abou-Zied, HA Hassan, BGM Youssif, ... Pharmaceuticals 16 (11), 1522, 2023 | | 2023 |
Chalcone Scaffold: A masterpiece for medicinal chemistry recent biological insights M Abdelaziz, HA Abou-Zied, EA Beshr, AM Hayallah Journal of advanced Biomedical and Pharmaceutical Sciences, 1-7, 2023 | | 2023 |
Discovery of new Schiff bases of the disalicylic acid scaffold as DNA gyrase and Topoisomerase IV inhibitors endowed with antibacterial properties LH Al-Wahaibi, MA Mahmoud, HA Alzahrani, HA Abou-Zied, HAM Gomaa, ... Frontiers in Chemistry 12, 1419242, 0 | | |