Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2 T Klemm, G Ebert, DJ Calleja, CC Allison, LW Richardson, JP Bernardini, ... The EMBO journal 39 (18), e106275, 2020 | 386 | 2020 |
Parkin and mitophagy in cancer JP Bernardini, M Lazarou, G Dewson Oncogene 36 (10), 1315-1327, 2017 | 248 | 2017 |
Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy JP Bernardini, JM Brouwer, IKL Tan, JJ Sandow, S Huang, CA Stafford, ... The EMBO journal 38 (2), e99916, 2019 | 86 | 2019 |
Distinct features of stress granule proteins predict localization in membraneless organelles ER Kuechler, PM Budzyńska, JP Bernardini, J Gsponer, T Mayor Journal of molecular biology 432 (7), 2349-2368, 2020 | 63 | 2020 |
Conversion of Bim-BH3 from activator to inhibitor of Bak through structure-based design JM Brouwer, P Lan, AD Cowan, JP Bernardini, RW Birkinshaw, ... Molecular cell 68 (4), 659-672. e9, 2017 | 59 | 2017 |
BAK core dimers bind lipids and can be bridged by them AD Cowan, NA Smith, JJ Sandow, EA Kapp, YH Rustam, JM Murphy, ... Nature structural & molecular biology 27 (11), 1024-1031, 2020 | 53 | 2020 |
IAPs regulate distinct innate immune pathways to co-ordinate the response to bacterial peptidoglycans CA Stafford, KE Lawlor, VJ Heim, A Bankovacki, JP Bernardini, J Silke, ... Cell Reports 22 (6), 1496-1508, 2018 | 34 | 2018 |
Mutant TRP53 exerts a target gene-selective dominant-negative effect to drive tumor development BJ Aubrey, A Janic, Y Chen, C Chang, EC Lieschke, ST Diepstraten, ... Genes & Development 32 (21-22), 1420-1429, 2018 | 31 | 2018 |
The BH3-only proteins BIM and PUMA are not critical for the reticulocyte apoptosis caused by loss of the pro-survival protein BCL-XL ARD Delbridge, BJ Aubrey, C Hyland, JP Bernardini, L Di Rago, ... Cell death & disease 8 (7), e2914-e2914, 2017 | 25 | 2017 |
Dynamic reconfiguration of pro‐apoptotic BAK on membranes JJ Sandow, IKL Tan, AS Huang, S Masaldan, JP Bernardini, AZ Wardak, ... The EMBO Journal 40 (20), e107237, 2021 | 22 | 2021 |
Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion I Pleines, M Lebois, P Gangatirkar, AE Au, RM Lane, KJ Henley, M Kauppi, ... Blood, The Journal of the American Society of Hematology 132 (2), 197-209, 2018 | 20 | 2018 |
Structural basis of K63-ubiquitin chain formation by the Gordon-Holmes syndrome RBR E3 ubiquitin ligase RNF216 TR Cotton, SA Cobbold, JP Bernardini, LW Richardson, XS Wang, ... Molecular cell 82 (3), 598-615. e8, 2022 | 19 | 2022 |
It's not just a phase; ubiquitination in cytosolic protein quality control HA Baker, JP Bernardini Biochemical Society Transactions 49 (1), 365-377, 2021 | 13 | 2021 |
Unfolding or aggregation, that is the question M Bolten, JP Bernardini, T Mayor Journal of Biological Chemistry 294 (45), 16525-16526, 2019 | 1 | 2019 |
The co-chaperone DNAJA2 buffers proteasomal degradation of cytosolic proteins with missense mutations HA Baker, JP Bernardini, V Csizmok, A Madero, S Kamat, H Eng, ... bioRxiv, 2024.02. 15.580437, 2024 | | 2024 |
Mechanism and inhibition of SARS-CoV-2 PLpro (preprint) T Klemm, G Ebert, DJ Calleja, CC Allison, LW Richardson, JP Bernardini, ... | | 2020 |