James T. Koerber
James T. Koerber
Principal Scientist, Dept. of Antibody Engineering, Genentech
Verified email at
Cited by
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Directed evolution of adeno-associated virus yields enhanced gene delivery vectors
N Maheshri, JT Koerber, BK Kaspar, DV Schaffer
Nature biotechnology 24 (2), 198-204, 2006
Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis
A Ordureau, SA Sarraf, DM Duda, JM Heo, MP Jedrychowski, ...
Molecular cell 56 (3), 360-375, 2014
A degradable polyethylenimine derivative with low toxicity for highly efficient gene delivery
ML Forrest, JT Koerber, DW Pack
Bioconjugate chemistry 14 (5), 934-940, 2003
Partial Acetylation of Polyethylenimine Enhances In Vitro Gene Delivery
ML Forrest, GE Meister, JT Koerber, DW Pack
Pharmaceutical research 21, 365-371, 2004
A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells
RR Klimczak, JT Koerber, D Dalkara, JG Flannery, DV Schaffer
PloS one 4 (10), e7467, 2009
Directed evolution of adeno-associated virus to an infectious respiratory virus
KJDA Excoffon, JT Koerber, DD Dickey, M Murtha, S Keshavjee, ...
Proceedings of the National Academy of Sciences 106 (10), 3865-3870, 2009
DNA shuffling of adeno-associated virus yields functionally diverse viral progeny
JT Koerber, JH Jang, DV Schaffer
Molecular Therapy 16 (10), 1703-1709, 2008
Molecular engineering of viral gene delivery vehicles
DV Schaffer, JT Koerber, K Lim
Annu. Rev. Biomed. Eng. 10, 169-194, 2008
Molecular evolution of adeno-associated virus for enhanced glial gene delivery
JT Koerber, R Klimczak, JH Jang, D Dalkara, JG Flannery, DV Schaffer
Molecular Therapy 17 (12), 2088-2095, 2009
Monoclonal antibody targeting the β-barrel assembly machine of Escherichia coli is bactericidal
KM Storek, MR Auerbach, H Shi, NK Garcia, D Sun, NN Nickerson, R Vij, ...
Proceedings of the National Academy of Sciences 115 (14), 3692-3697, 2018
An evolved adeno-associated viral variant enhances gene delivery and gene targeting in neural stem cells
JH Jang, JT Koerber, JS Kim, P Asuri, T Vazin, M Bartel, A Keung, I Kwon, ...
Molecular Therapy 19 (4), 667-675, 2011
Avidity-based binding to HER2 results in selective killing of HER2-overexpressing cells by anti-HER2/CD3
D Slaga, D Ellerman, TN Lombana, R Vij, J Li, M Hristopoulos, R Clark, ...
Science translational medicine 10 (463), eaat5775, 2018
Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab
L Rougé, N Chiang, M Steffek, C Kugel, TI Croll, C Tam, A Estevez, ...
Science 367 (6483), 1224-1230, 2020
Construction of diverse adeno-associated viral libraries for directed evolution of enhanced gene delivery vehicles
JT Koerber, N Maheshri, BK Kaspar, DV Schaffer
Nature protocols 1 (2), 701-706, 2006
An allosteric anti-tryptase antibody for the treatment of mast cell-mediated severe asthma
HR Maun, JK Jackman, DF Choy, KM Loyet, TL Staton, G Jia, A Dressen, ...
Cell 179 (2), 417-431. e19, 2019
Adeno-associated virus virions with variant capsid and methods of use thereof
DV Schaffer, RR Klimczak, JT Koerber, JG Flannery, DD Mourot, M Visel, ...
US Patent 9,193,956, 2015
Nature-inspired design of motif-specific antibody scaffolds
JT Koerber, ND Thomsen, BT Hannigan, WF Degrado, JA Wells
Nature biotechnology 31 (10), 916-921, 2013
Adeno-associated virus virions with variant capsid and methods of use thereof
DV Schaffer, RR Klimczak, JT Koerber, JG Flannery
US Patent 9,457,103, 2016
Engineering adeno-associated virus for one-step purification via immobilized metal affinity chromatography
JT Koerber, JH Jang, JH Yu, RS Kane, DV Schaffer
Human gene therapy 18 (4), 367-378, 2007
Structural snapshots reveal distinct mechanisms of procaspase-3 and-7 activation
ND Thomsen, JT Koerber, JA Wells
Proceedings of the National Academy of Sciences 110 (21), 8477-8482, 2013
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