James T. Koerber
James T. Koerber
Principal Scientist, Dept. of Antibody Engineering, Genentech
Verified email at
Cited by
Cited by
Directed evolution of adeno-associated virus yields enhanced gene delivery vectors
N Maheshri, JT Koerber, BK Kaspar, DV Schaffer
Nature biotechnology 24 (2), 198-204, 2006
Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis
A Ordureau, SA Sarraf, DM Duda, JM Heo, MP Jedrychowski, ...
Molecular cell 56 (3), 360-375, 2014
A degradable polyethylenimine derivative with low toxicity for highly efficient gene delivery
ML Forrest, JT Koerber, DW Pack
Bioconjugate chemistry 14 (5), 934-940, 2003
Partial acetylation of polyethylenimine enhances in vitro gene delivery
ML Forrest, GE Meister, JT Koerber, DW Pack
Pharmaceutical research 21 (2), 365-371, 2004
A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells
RR Klimczak, JT Koerber, D Dalkara, JG Flannery, DV Schaffer
PloS one 4 (10), e7467, 2009
Molecular engineering of viral gene delivery vehicles
DV Schaffer, JT Koerber, K Lim
Annual review of biomedical engineering 10, 169, 2008
DNA shuffling of adeno-associated virus yields functionally diverse viral progeny
JT Koerber, JH Jang, DV Schaffer
Molecular Therapy 16 (10), 1703-1709, 2008
Molecular evolution of adeno-associated virus for enhanced glial gene delivery
JT Koerber, R Klimczak, JH Jang, D Dalkara, JG Flannery, DV Schaffer
Molecular Therapy 17 (12), 2088-2095, 2009
Directed evolution of adeno-associated virus to an infectious respiratory virus
KJDA Excoffon, JT Koerber, DD Dickey, M Murtha, S Keshavjee, ...
Proceedings of the National Academy of Sciences 106 (10), 3865-3870, 2009
An evolved adeno-associated viral variant enhances gene delivery and gene targeting in neural stem cells
JH Jang, JT Koerber, JS Kim, P Asuri, T Vazin, M Bartel, A Keung, I Kwon, ...
Molecular Therapy 19 (4), 667-675, 2011
Monoclonal antibody targeting the β-barrel assembly machine of Escherichia coli is bactericidal
KM Storek, MR Auerbach, H Shi, NK Garcia, D Sun, NN Nickerson, R Vij, ...
Proceedings of the National Academy of Sciences 115 (14), 3692-3697, 2018
Construction of diverse adeno-associated viral libraries for directed evolution of enhanced gene delivery vehicles
JT Koerber, N Maheshri, BK Kaspar, DV Schaffer
Nature protocols 1 (2), 701-706, 2006
Avidity-based binding to HER2 results in selective killing of HER2-overexpressing cells by anti-HER2/CD3
D Slaga, D Ellerman, TN Lombana, R Vij, J Li, M Hristopoulos, R Clark, ...
Science translational medicine 10 (463), eaat5775, 2018
Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab
L Rougé, N Chiang, M Steffek, C Kugel, TI Croll, C Tam, A Estevez, ...
Science 367 (6483), 1224-1230, 2020
Nature-inspired design of motif-specific antibody scaffolds
JT Koerber, ND Thomsen, BT Hannigan, WF Degrado, JA Wells
Nature biotechnology 31 (10), 916-921, 2013
Engineering adeno-associated virus for one-step purification via immobilized metal affinity chromatography
JT Koerber, JH Jang, JH Yu, RS Kane, DV Schaffer
Human gene therapy 18 (4), 367-378, 2007
An allosteric anti-tryptase antibody for the treatment of mast cell-mediated severe asthma
HR Maun, JK Jackman, DF Choy, KM Loyet, TL Staton, G Jia, A Dressen, ...
Cell 179 (2), 417-431. e19, 2019
Adeno-associated virus virions with variant capsid and methods of use thereof
DV Schaffer, RR Klimczak, JT Koerber, JG Flannery, DD Mourot, M Visel, ...
US Patent 9,193,956, 2015
Structural snapshots reveal distinct mechanisms of procaspase-3 and-7 activation
ND Thomsen, JT Koerber, JA Wells
Proceedings of the National Academy of Sciences 110 (21), 8477-8482, 2013
Adeno-associated virus virions with variant capsid and methods of use thereof
DV Schaffer, RR Klimczak, JT Koerber, JG Flannery
US Patent 9,457,103, 2016
The system can't perform the operation now. Try again later.
Articles 1–20