| Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway P Jin, DC Zarnescu, S Ceman, M Nakamoto, J Mowrey, TA Jongens, ... Nature neuroscience 7 (2), 113-117, 2004 | 808 | 2004 |
| TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD CC Chou, YI Zhang, ME Umoh, SW Vaughan, I Lorenzini, F Liu, ... Nature neuroscience 21 (2), 228-239, 2018 | 488 | 2018 |
| RNA-mediated neurodegeneration caused by the fragile X premutation rCGG repeats in Drosophila P Jin, DC Zarnescu, F Zhang, CE Pearson, JC Lucchesi, K Moses, ... Neuron 39 (5), 739-747, 2003 | 396 | 2003 |
| Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila S Chang, SM Bray, Z Li, DC Zarnescu, C He, P Jin, ST Warren Nature chemical biology 4 (4), 256-263, 2008 | 307 | 2008 |
| Crumbs interacts with moesin and βHeavy-spectrin in the apical membrane skeleton of Drosophila E Médina, J Williams, E Klipfell, D Zarnescu, CM Thomas, A Le Bivic The Journal of cell biology 158 (5), 941-951, 2002 | 226 | 2002 |
| Wild-type and A315T mutant TDP-43 exert differential neurotoxicity in a Drosophila model of ALS PS Estes, A Boehringer, R Zwick, JE Tang, B Grigsby, DC Zarnescu Human molecular genetics 20 (12), 2308-2321, 2011 | 198 | 2011 |
| Futsch/MAP1B mRNA is a translational target of TDP-43 and is neuroprotective in a Drosophila model of amyotrophic lateral sclerosis AN Coyne, BB Siddegowda, PS Estes, J Johannesmeyer, T Kovalik, ... Journal of Neuroscience 34 (48), 15962-15974, 2014 | 166 | 2014 |
| Mutations disrupting neuritogenesis genes confer risk for cerebral palsy SC Jin, SA Lewis, S Bakhtiari, X Zeng, MC Sierant, S Shetty, SM Nordlie, ... Nature genetics 52 (10), 1046-1056, 2020 | 123 | 2020 |
| Apical Spectrin Is Essential for Epithelial Morphogenesis but Not Apicobasal Polarity in Drosophila DC Zarnescu, CM Thomas The Journal of cell biology 146 (5), 1075-1086, 1999 | 122 | 1999 |
| Fragile X protein controls the efficacy of mRNA transport in Drosophila neurons PS Estes, M O’Shea, S Clasen, DC Zarnescu Molecular and Cellular Neuroscience 39 (2), 170-179, 2008 | 107 | 2008 |
| Endocytosis regulates TDP-43 toxicity and turnover G Liu, AN Coyne, F Pei, S Vaughan, M Chaung, DC Zarnescu, JR Buchan Nature communications 8 (1), 2092, 2017 | 103 | 2017 |
| Post-transcriptional inhibition of Hsc70-4/HSPA8 expression leads to synaptic vesicle cycling defects in multiple models of ALS AN Coyne, I Lorenzini, CC Chou, M Torvund, RS Rogers, A Starr, ... Cell reports 21 (1), 110-125, 2017 | 96 | 2017 |
| Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis PS Estes, SG Daniel, AP Mccallum, AV Boehringer, AS Sukhina, ... Disease models & mechanisms 6 (3), 721-733, 2013 | 94 | 2013 |
| Glycolysis upregulation is neuroprotective as a compensatory mechanism in ALS E Manzo, I Lorenzini, D Barrameda, AG O'Conner, JM Barrows, A Starr, ... Elife 8, e45114, 2019 | 91 | 2019 |
| Fragile X protein functions with lgl and the par complex in flies and mice DC Zarnescu, P Jin, J Betschinger, M Nakamoto, Y Wang, TC Dockendorff, ... Developmental cell 8 (1), 43-52, 2005 | 87 | 2005 |
| Fragile X protein mitigates TDP-43 toxicity by remodeling RNA granules and restoring translation AN Coyne, SB Yamada, BB Siddegowda, PS Estes, BL Zaepfel, ... Human molecular genetics 24 (24), 6886-6898, 2015 | 86 | 2015 |
| Fragile X protein controls neural stem cell proliferation in the Drosophila brain MA Callan, C Cabernard, J Heck, S Luois, CQ Doe, DC Zarnescu Human molecular genetics 19 (15), 3068-3079, 2010 | 86 | 2010 |
| Drosophila βHeavy-spectrin is essential for development and contributes to specific cell fates in the eye CM Thomas, DC Zarnescu, AE Juedes, MA Bales, A Londergan, CC Korte, ... Development 125 (11), 2125-2134, 1998 | 82 | 1998 |
| PPAR gamma activation is neuroprotective in a Drosophila model of ALS based on TDP-43 A Joardar, J Menzl, TC Podolsky, E Manzo, PS Estes, S Ashford, ... Human molecular genetics 24 (6), 1741-1754, 2015 | 76 | 2015 |
| Desmoplakin and Talin2 Are Novel mRNA Targets of Fragile X–Related Protein-1 in Cardiac Muscle SA Whitman, C Cover, L Yu, DL Nelson, DC Zarnescu, CC Gregorio Circulation research 109 (3), 262-271, 2011 | 57 | 2011 |
