Pharmacological activation of IKr in models of long QT Type 2 risks overcorrection of repolarization MD Perry, CA Ng, MM Mangala, TYM Ng, AD Hines, W Liang, MJO Xu, ... Cardiovascular research 116 (8), 1434-1445, 2020 | 31 | 2020 |
Co-expression of calcium and hERG potassium channels reduces the incidence of proarrhythmic events S Ballouz, MM Mangala, MD Perry, S Heitmann, JA Gillis, AP Hill, ... Cardiovascular Research 117 (10), 2216-2227, 2021 | 21 | 2021 |
Real-time monitoring of peptide grafting onto chitosan films using capillary electrophoresis DL Taylor, JJ Thevarajah, DK Narayan, P Murphy, MM Mangala, S Lim, ... Analytical and Bioanalytical Chemistry 407, 2543-2555, 2015 | 19 | 2015 |
Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation C TeBay, JR McArthur, M Mangala, N Kerr, S Heitmann, MD Perry, ... British Journal of Pharmacology 179 (11), 2631-2646, 2022 | 9 | 2022 |
Development of induced pluripotent stem cells from a patient with hypertrophic cardiomyopathy who carries the pathogenic myosin heavy chain 7 mutation p. Arg403Gln M Holliday, SB Ross, S Lim, M Mangala, A Hill, HC Szappanos, L Hool, ... Stem Cell Research 33, 269-273, 2018 | 4 | 2018 |
Co-expression of calcium channels and delayed rectifier potassium channels protects the heart from proarrhythmic events S Ballouz, MM Mangala, MD Perry, S Heitmann, JA Gillis, AP Hill, ... bioRxiv, 659821, 2019 | 3 | 2019 |
Action Potential Morphology Accurately Predicts Proarrhythmic Risk for Drugs With Potential to Prolong Cardiac Repolarization W Lee, B Ng, MM Mangala, MD Perry, RN Subbiah, JI Vandenberg, ... Circulation: Arrhythmia and Electrophysiology 16 (7), 399-410, 2023 | 2 | 2023 |
Comprehensive preclinical evaluation of how cardiac safety profiles of potential COVID-19 drugs are modified by disease associated factors. C TeBay, J McArthur, M Mangala, N Kerr, S Heitmann, M Perry, M Windley, ... Authorea Preprints, 2021 | 2 | 2021 |
Cytoskeletal disarray increases arrhythmogenic vulnerability during sympathetic stimulation in a model of hypertrophic cardiomyopathy H Cserne Szappanos, HM Viola, DW Ito, S Lim, M Mangala, M Holliday, ... Scientific Reports 13 (1), 11296, 2023 | 1 | 2023 |
Slow conduction and spatial dispersion of repolarization are intrinsic properties of cardiomyocyte electrophysiology that contribute to proarrhythmia in an iPSC model of … SC Lim, MM Mangala, M Holliday, HC Szappanos, S Barratt-Ross, ... bioRxiv, 2023.07. 20.549952, 2023 | | 2023 |
Comprehensive preclinical evaluation of how cardiac safety profiles of chloroquine and hydroxychloroquine are modified by disease associated factors C TeBay, JR MacArthur, M Mangala, N Kerr, S Heitmann, MD Perry, ... JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS 117, 2022 | | 2022 |
Slow Conduction Velocity Revealed in Hypertrophic Cardiomyopathy Modelled With Patient-Derived Induced Pluripotent Stem Cell Cardiomyocytes S Lim, M Mangala, M Holliday, S Ross, W Liang, G Ranpura, ... Heart, Lung and Circulation 31, S11-S12, 2022 | | 2022 |
Functional Analysis of a Novel Heterozygous Variant in CASQ2 as a Distinct Cause of Catecholaminergic Polymorphic Ventricular Tachycardia S Ross, M Holliday, S Lim, M Mangala, M Perry, B Gray, S Fraser, A Hill, ... Heart, Lung and Circulation 30, S96, 2021 | | 2021 |
Novel Pre–Clinical Risk Prediction of Acquired Long QT Syndrome W Lee, M Mangala, M Windley, M Perry, J Vandenberg, A Hill Heart, Lung and Circulation 27, S180, 2018 | | 2018 |
Endogenous expression of mutant BEST1 results in decreased Cl-and Ca2+ conductance in human retinal pigment epithelium. M D O'Connor, M Mangala, M Cameron, J Morley Investigative Ophthalmology & Visual Science 57 (12), 2016 | | 2016 |
Investigating the role of BEST1 protein in Best vitelliform macular dystrophy using a novel, disease-specific human embryonic stem cell line MM Mangala PQDT-Global, 2016 | | 2016 |
Modelling Best Vitelliform Macular Dystrophy with human embryonic stem cells MD O'Connor, MM Mangala, U Schmidt Investigative Ophthalmology & Visual Science 53 (14), 5207-5207, 2012 | | 2012 |
Novel ocular therapies from new cell sources MD O'Connor, PA Murphy, M Mangala, S Lim Optometry Pharma, 8-11, 2012 | | 2012 |
307 Stem Cells: Disease Models and Therapeutics I MD O'Connor, M Mangala, M Cameron, J Morley | | |