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Melissa Mangala
Melissa Mangala
Victor Chang Cardiac Research Institute
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Cited by
Year
Pharmacological activation of IKr in models of long QT Type 2 risks overcorrection of repolarization
MD Perry, CA Ng, MM Mangala, TYM Ng, AD Hines, W Liang, MJO Xu, ...
Cardiovascular research 116 (8), 1434-1445, 2020
312020
Co-expression of calcium and hERG potassium channels reduces the incidence of proarrhythmic events
S Ballouz, MM Mangala, MD Perry, S Heitmann, JA Gillis, AP Hill, ...
Cardiovascular Research 117 (10), 2216-2227, 2021
212021
Real-time monitoring of peptide grafting onto chitosan films using capillary electrophoresis
DL Taylor, JJ Thevarajah, DK Narayan, P Murphy, MM Mangala, S Lim, ...
Analytical and Bioanalytical Chemistry 407, 2543-2555, 2015
192015
Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation
C TeBay, JR McArthur, M Mangala, N Kerr, S Heitmann, MD Perry, ...
British Journal of Pharmacology 179 (11), 2631-2646, 2022
92022
Development of induced pluripotent stem cells from a patient with hypertrophic cardiomyopathy who carries the pathogenic myosin heavy chain 7 mutation p. Arg403Gln
M Holliday, SB Ross, S Lim, M Mangala, A Hill, HC Szappanos, L Hool, ...
Stem Cell Research 33, 269-273, 2018
42018
Co-expression of calcium channels and delayed rectifier potassium channels protects the heart from proarrhythmic events
S Ballouz, MM Mangala, MD Perry, S Heitmann, JA Gillis, AP Hill, ...
bioRxiv, 659821, 2019
32019
Action Potential Morphology Accurately Predicts Proarrhythmic Risk for Drugs With Potential to Prolong Cardiac Repolarization
W Lee, B Ng, MM Mangala, MD Perry, RN Subbiah, JI Vandenberg, ...
Circulation: Arrhythmia and Electrophysiology 16 (7), 399-410, 2023
22023
Comprehensive preclinical evaluation of how cardiac safety profiles of potential COVID-19 drugs are modified by disease associated factors.
C TeBay, J McArthur, M Mangala, N Kerr, S Heitmann, M Perry, M Windley, ...
Authorea Preprints, 2021
22021
Cytoskeletal disarray increases arrhythmogenic vulnerability during sympathetic stimulation in a model of hypertrophic cardiomyopathy
H Cserne Szappanos, HM Viola, DW Ito, S Lim, M Mangala, M Holliday, ...
Scientific Reports 13 (1), 11296, 2023
12023
Slow conduction and spatial dispersion of repolarization are intrinsic properties of cardiomyocyte electrophysiology that contribute to proarrhythmia in an iPSC model of …
SC Lim, MM Mangala, M Holliday, HC Szappanos, S Barratt-Ross, ...
bioRxiv, 2023.07. 20.549952, 2023
2023
Comprehensive preclinical evaluation of how cardiac safety profiles of chloroquine and hydroxychloroquine are modified by disease associated factors
C TeBay, JR MacArthur, M Mangala, N Kerr, S Heitmann, MD Perry, ...
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS 117, 2022
2022
Slow Conduction Velocity Revealed in Hypertrophic Cardiomyopathy Modelled With Patient-Derived Induced Pluripotent Stem Cell Cardiomyocytes
S Lim, M Mangala, M Holliday, S Ross, W Liang, G Ranpura, ...
Heart, Lung and Circulation 31, S11-S12, 2022
2022
Functional Analysis of a Novel Heterozygous Variant in CASQ2 as a Distinct Cause of Catecholaminergic Polymorphic Ventricular Tachycardia
S Ross, M Holliday, S Lim, M Mangala, M Perry, B Gray, S Fraser, A Hill, ...
Heart, Lung and Circulation 30, S96, 2021
2021
Novel Pre–Clinical Risk Prediction of Acquired Long QT Syndrome
W Lee, M Mangala, M Windley, M Perry, J Vandenberg, A Hill
Heart, Lung and Circulation 27, S180, 2018
2018
Endogenous expression of mutant BEST1 results in decreased Cl-and Ca2+ conductance in human retinal pigment epithelium.
M D O'Connor, M Mangala, M Cameron, J Morley
Investigative Ophthalmology & Visual Science 57 (12), 2016
2016
Investigating the role of BEST1 protein in Best vitelliform macular dystrophy using a novel, disease-specific human embryonic stem cell line
MM Mangala
PQDT-Global, 2016
2016
Modelling Best Vitelliform Macular Dystrophy with human embryonic stem cells
MD O'Connor, MM Mangala, U Schmidt
Investigative Ophthalmology & Visual Science 53 (14), 5207-5207, 2012
2012
Novel ocular therapies from new cell sources
MD O'Connor, PA Murphy, M Mangala, S Lim
Optometry Pharma, 8-11, 2012
2012
307 Stem Cells: Disease Models and Therapeutics I
MD O'Connor, M Mangala, M Cameron, J Morley
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Articles 1–19