Transcriptional plasticity promotes primary and acquired resistance to BET inhibition P Rathert, M Roth, T Neumann, F Muerdter, JS Roe, M Muhar, S Deswal, ... Nature 525 (7570), 543-547, 2015 | 496 | 2015 |
Thiol-linked alkylation of RNA to assess expression dynamics VA Herzog, B Reichholf, T Neumann, P Rescheneder, P Bhat, TR Burkard, ... Nature methods 14 (12), 1198-1204, 2017 | 472 | 2017 |
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis M Muhar, A Ebert, T Neumann, C Umkehrer, J Jude, C Wieshofer, ... Science 360 (6390), 800-805, 2018 | 308 | 2018 |
The First Myriapod Genome Sequence Reveals Conservative Arthropod Gene Content and Genome Organisation in the Centipede Strigamia maritima AD Chipman, DEK Ferrier, C Brena, J Qu, DST Hughes, R Schröder, ... PLoS biology 12 (11), e1002005, 2014 | 253 | 2014 |
Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma L Haas, A Elewaut, CL Gerard, C Umkehrer, L Leiendecker, M Pedersen, ... Nature Cancer 2 (7), 693-708, 2021 | 126 | 2021 |
Cohesin-dependent and-independent mechanisms mediate chromosomal contacts between promoters and enhancers MJ Thiecke, G Wutz, M Muhar, W Tang, S Bevan, V Malysheva, R Stocsits, ... Cell reports 32 (3), 2020 | 124 | 2020 |
The genomic basis of circadian and circalunar timing adaptations in a midge TS Kaiser, B Poehn, D Szkiba, M Preussner, FJ Sedlazeck, A Zrim, ... Nature 540 (7631), 69-73, 2016 | 103 | 2016 |
Quantification of experimentally induced nucleotide conversions in high-throughput sequencing datasets T Neumann, VA Herzog, M Muhar, A von Haeseler, J Zuber, SL Ameres, ... BMC bioinformatics 20, 1-16, 2019 | 94 | 2019 |
Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles G Michlits, J Jude, M Hinterndorfer, M de Almeida, G Vainorius, ... Nature Methods 17 (7), 708-716, 2020 | 81 | 2020 |
Regulation of RNA polymerase II processivity by Spt5 is restricted to a narrow window during elongation J Fitz, T Neumann, R Pavri The EMBO journal 37 (8), e97965, 2018 | 73 | 2018 |
Isolating live cell clones from barcoded populations using CRISPRa-inducible reporters C Umkehrer, F Holstein, L Formenti, J Jude, K Froussios, T Neumann, ... Nature Biotechnology 39 (2), 174-178, 2021 | 70 | 2021 |
AKIRIN2 controls the nuclear import of proteasomes in vertebrates M de Almeida, M Hinterndorfer, H Brunner, I Grishkovskaya, K Singh, ... Nature 599 (7885), 491-496, 2021 | 65 | 2021 |
A rapid, highly sensitive and open-access SARS-CoV-2 detection assay for laboratory and home testing MJ Kellner, JJ Ross, J Schnabl, MPS Dekens, M Matl, R Heinen, ... Frontiers in Molecular Biosciences 9, 801309, 2022 | 64 | 2022 |
Spt5-mediated enhancer transcription directly couples enhancer activation with physical promoter interaction J Fitz, T Neumann, M Steininger, EM Wiedemann, AC Garcia, ... Nature Genetics 52 (5), 505-515, 2020 | 59 | 2020 |
LSD 1 inhibition induces differentiation and cell death in Merkel cell carcinoma L Leiendecker, PS Jung, I Krecioch, T Neumann, A Schleiffer, K Mechtler, ... EMBO molecular medicine 12 (11), e12525, 2020 | 43 | 2020 |
Multiplexed detection of SARS-CoV-2 and other respiratory infections in high throughput by SARSeq R Yelagandula, A Bykov, A Vogt, R Heinen, E Özkan, MM Strobl, JC Baar, ... Nature Communications 12 (1), 3132, 2021 | 38 | 2021 |
SLAM-ITseq: sequencing cell type-specific transcriptomes without cell sorting W Matsushima, VA Herzog, T Neumann, K Gapp, J Zuber, SL Ameres, ... Development 145 (13), dev164640, 2018 | 36 | 2018 |
DNA replication timing directly regulates the frequency of oncogenic chromosomal translocations M Peycheva, T Neumann, D Malzl, M Nazarova, UE Schoeberl, R Pavri Science 377 (6612), eabj5502, 2022 | 21 | 2022 |
Human papillomavirus 42 drives digital papillary adenocarcinoma and elicits a germ cell–like program conserved in HPV-positive cancers L Leiendecker, T Neumann, PS Jung, SM Cronin, TL Steinacker, ... Cancer Discovery 13 (1), 70-84, 2023 | 17 | 2023 |
Sequencing cell-type-specific transcriptomes with SLAM-ITseq W Matsushima, VA Herzog, T Neumann, K Gapp, J Zuber, SL Ameres, ... Nature protocols 14 (8), 2261-2278, 2019 | 16 | 2019 |