| Ultra-sensitive TP53 sequencing for cancer detection reveals progressive clonal selection in normal tissue over a century of human lifespan JJ Salk, K Loubet-Senear, E Maritschnegg, CC Valentine, LN Williams, ... Cell Reports 28 (1), 132-144. e3, 2019 | 74 | 2019 |
| Targeted genome fragmentation with CRISPR/Cas9 enables fast and efficient enrichment of small genomic regions and ultra-accurate sequencing with low DNA input (CRISPR-DS) D Nachmanson, S Lian, EK Schmidt, MJ Hipp, KT Baker, Y Zhang, ... Genome Research 28 (10), 1589-1599, 2018 | 46 | 2018 |
| Inhibition of mTOR signaling and clinical activity of metformin in oral premalignant lesions JS Gutkind, AA Molinolo, X Wu, Z Wang, D Nachmanson, O Harismendy, ... JCI insight 6 (17), 2021 | 39 | 2021 |
| Targeted deletion of AKAP7 in dentate granule cells impairs spatial discrimination BW Jones, J Deem, TJ Younts, M Weisenhaus, CA Sanford, MC Slack, ... Elife 5, e20695, 2016 | 35 | 2016 |
| Mitochondrial DNA mutations are associated with ulcerative colitis preneoplasia but tend to be negatively selected in cancer KT Baker, D Nachmanson, S Kumar, MJ Emond, C Ussakli, TA Brentnall, ... Molecular Cancer Research 17 (2), 488-498, 2019 | 30 | 2019 |
| The breast pre-cancer atlas illustrates the molecular and micro-environmental diversity of ductal carcinoma in situ D Nachmanson, A Officer, H Mori, J Gordon, MF Evans, J Steward, H Yao, ... NPJ Breast Cancer 8 (1), 6, 2022 | 16 | 2022 |
| Characterization of TP53 mutations in Pap test DNA of women with and without serous ovarian carcinoma JD Krimmel-Morrison, TS Ghezelayagh, S Lian, Y Zhang, J Fredrickson, ... Gynecologic oncology 156 (2), 407-414, 2020 | 11 | 2020 |
| Whole-genome CRISPR screening identifies PI3K/AKT as a downstream component of the oncogenic GNAQ–focal adhesion kinase signaling circuitry N Arang, S Lubrano, DC Rigiracciolo, D Nachmanson, SM Lippman, ... Journal of Biological Chemistry 299 (2), 2023 | 6 | 2023 |
| Prevalence of cancer susceptibility variants in patients with multiple Lynch syndrome related cancers YY Choi, SJ Shin, JE Lee, L Madlensky, ST Lee, JS Park, JH Jo, H Kim, ... Scientific reports 11 (1), 14807, 2021 | 6 | 2021 |
| Methods for targeted nucleic acid sequence enrichment with applications to error corrected nucleic acid sequencing SR Kennedy, M Hipp, E Schmidt, RA Risques, D Nachmanson US Patent 11,479,807, 2022 | 4 | 2022 |
| Mutational profiling of micro-dissected pre-malignant lesions from archived specimens D Nachmanson, J Steward, H Yao, A Officer, E Jeong, TJ O’Keefe, ... BMC Medical Genomics 13, 1-15, 2020 | 4 | 2020 |
| Adopting duplex sequencing technology for genetic toxicity testing: A proof-of-concept mutagenesis experiment with N-ethyl-N-nitrosourea (ENU)-exposed rats SL Smith-Roe, CA Hobbs, V Hull, JT Auman, L Recio, MA Streicker, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 891, 503669, 2023 | 3 | 2023 |
| Targeted genome fragmentation with CRISPR/Cas9 improves hybridization capture, reduces PCR bias, and enables efficient high-accuracy sequencing of small targets D Nachmanson, S Lian, EK Schmidt, MJ Hipp, KT Baker, Y Zhang, ... bioRxiv, 207027, 2017 | 3 | 2017 |
| Accurate genome-wide genotyping from archival tissue to explore the contribution of common genetic variants to pre-cancer outcomes D Nachmanson, M Pagadala, J Steward, C Cheung, LK Bruce, NQ Lee, ... Journal of Translational Medicine 20 (1), 623, 2022 | 2 | 2022 |
| PolyG-DS: An ultrasensitive polyguanine tract–profiling method to detect clonal expansions and trace cell lineage Y Zhang, BF Kohrn, M Yang, D Nachmanson, TR Soong, IH Lee, Y Tao, ... Proceedings of the National Academy of Sciences 118 (31), e2023373118, 2021 | 2 | 2021 |
| CRISPR-DS: an efficient, low DNA input method for ultra-accurate sequencing D Nachmanson, S Lian, EK Schmidt, MJ Hipp, KT Baker, Y Zhang, ... bioRxiv, 207027, 2017 | 2 | 2017 |
| Integrated Molecular Characterization of Intraductal Papillary Mucinous Neoplasms: An NCI Cancer Moonshot Precancer Atlas Pilot Project A Semaan, V Bernard, J Wong, Y Makino, DB Swartzlander, ... Cancer Research Communications 3 (10), 2062-2073, 2023 | 1 | 2023 |
| Accurate genome-wide germline profiling from decade-old archival tissue DNA reveals the contribution of common variants to precancer disease outcome D Nachmanson, M Pagadala, J Steward, C Cheung, LK Bruce, NQ Lee, ... medRxiv, 2022.03. 31.22273116, 2022 | 1 | 2022 |
| Ultra-sensitive sequencing for cancer detection reveals progressive clonal selection in normal tissue over a century of human lifespan JJ Salk, K Loubet-Senear, E Maritschnegg, CC Valentine, LN Williams, ... bioRxiv, 457291, 2018 | 1 | 2018 |
| Frequency and spectrum of mutations in human sperm measured using duplex sequencing correlate with trio-based de novo mutation analyses J Axelsson, D LeBlanc, H Shojaeisaadi, MJ Meier, DM Fitzgerald, ... medRxiv, 2024.02. 13.24302689, 2024 | | 2024 |
