PLGA-PEG-ANG-2 nanoparticles for blood–brain barrier crossing: Proof-of-concept study GP Hoyos-Ceballos, B Ruozi, I Ottonelli, F Da Ros, MA Vandelli, F Forni, ... Pharmaceutics 12 (1), 72, 2020 | 55 | 2020 |
Targeting brain disease in MPSII: preclinical evaluation of IDS-loaded PLGA nanoparticles L Rigon, M Salvalaio, F Pederzoli, E Legnini, JT Duskey, F D’Avanzo, ... International journal of molecular sciences 20 (8), 2014, 2019 | 49 | 2019 |
Autism-associated SHANK3 mutations impair maturation of neuromuscular junctions and striated muscles AK Lutz, S Pfaender, B Incearap, V Ioannidis, I Ottonelli, KJ Föhr, ... Science Translational Medicine 12 (547), eaaz3267, 2020 | 41 | 2020 |
Insights into kinetics, release, and behavioral effects of brain-targeted hybrid nanoparticles for cholesterol delivery in Huntington's disease G Birolini, M Valenza, I Ottonelli, A Passoni, M Favagrossa, JT Duskey, ... Journal of controlled release 330, 587-598, 2021 | 39 | 2021 |
Novel peptide-conjugated nanomedicines for brain targeting: In vivo evidence JT Duskey, I Ottonelli, F Da Ros, A Vilella, M Zoli, S Kovachka, F Spyrakis, ... Nanomedicine: Nanotechnology, Biology and Medicine 28, 102226, 2020 | 22 | 2020 |
Investigating novel syntheses of a series of unique hybrid PLGA-chitosan polymers for potential therapeutic delivery applications JT Duskey, C Baraldi, MC Gamberini, I Ottonelli, F Da Ros, G Tosi, F Forni, ... Polymers 12 (4), 823, 2020 | 22 | 2020 |
Nanomedicine against Aβ aggregation by β–sheet breaker peptide delivery: In vitro evidence F Pederzoli, B Ruozi, J Duskey, S Hagmeyer, AK Sauer, S Grabrucker, ... Pharmaceutics 11 (11), 572, 2019 | 21 | 2019 |
Enzyme stability in nanoparticle preparations Part 1: Bovine serum albumin improves enzyme function JT Duskey, F da Ros, I Ottonelli, B Zambelli, MA Vandelli, G Tosi, B Ruozi Molecules 25 (20), 4593, 2020 | 19 | 2020 |
Tunneling nanotubes: a new target for nanomedicine? I Ottonelli, R Caraffi, G Tosi, MA Vandelli, JT Duskey, B Ruozi International Journal of Molecular Sciences 23 (4), 2237, 2022 | 16 | 2022 |
Optimization of an Injectable Hydrogel Depot System for the Controlled Release of Retinal-Targeted Hybrid Nanoparticles I Ottonelli, A Bighinati, E Adani, F Loll, R Caraffi, MA Vandelli, F Boury, ... Pharmaceutics 15 (1), 25, 2022 | 13 | 2022 |
Tween® Preserves Enzyme Activity and Stability in PLGA Nanoparticles JT Duskey, I Ottonelli, A Rinaldi, I Parmeggiani, B Zambelli, LZ Wang, ... Nanomaterials 11 (11), 2946, 2021 | 12 | 2021 |
Microfluidic technology for the production of hybrid nanomedicines I Ottonelli, JT Duskey, A Rinaldi, MV Grazioli, I Parmeggiani, MA Vandelli, ... Pharmaceutics 13 (9), 1495, 2021 | 12 | 2021 |
Hyaluronic acid scaffolds for loco-regional therapy in nervous system related disorders A Djoudi, R Molina-Peña, N Ferreira, I Ottonelli, G Tosi, E Garcion, ... International Journal of Molecular Sciences 23 (20), 12174, 2022 | 10 | 2022 |
Glioblastoma multiforme selective nanomedicines for improved anti-cancer treatments JT Duskey, A Rinaldi, I Ottonelli, R Caraffi, CA De Benedictis, AK Sauer, ... Pharmaceutics 14 (7), 1450, 2022 | 9 | 2022 |
Quantitative comparison of the protein corona of nanoparticles with different matrices I Ottonelli, JT Duskey, F Genovese, F Pederzoli, R Caraffi, M Valenza, ... International Journal of Pharmaceutics: X 4, 100136, 2022 | 7 | 2022 |
Recent advances on surface-modified GBM targeted nanoparticles: targeting strategies and surface characterization F Rodà, R Caraffi, S Picciolini, G Tosi, MA Vandelli, B Ruozi, M Bedoni, ... International Journal of Molecular Sciences 24 (3), 2496, 2023 | 5 | 2023 |
“Combo” Multi-Target Pharmacological Therapy and New Formulations to Reduce Inflammation and Improve Endogenous Remyelination in Traumatic Spinal Cord Injury M Moretti, R Caraffi, L Lorenzini, I Ottonelli, M Sannia, G Alastra, ... Cells 12 (9), 1331, 2023 | 2 | 2023 |
C-end rule peptide-guided niosomes for prostate cancer cell targeting N d’Avanzo, V Sidorenko, L Simón-Gracia, A Rocchi, I Ottonelli, B Ruozi, ... Journal of Drug Delivery Science and Technology 91, 105162, 2024 | 1 | 2024 |
Chronic cholesterol administration to the brain supports complete and long-lasting cognitive and motor amelioration in Huntington’s disease G Birolini, M Valenza, I Ottonelli, F Talpo, L Minoli, A Cappelleri, ... Pharmacological Research 194, 106823, 2023 | 1 | 2023 |
I17 Sustained benefits of brain-permeable cholesterol-loaded nanoparticles in zQ175DN mouse model M Valenza, G Birolini, I Ottonelli, F Talpo, A Passoni, M Favagrossa, ... Journal of Neurology, Neurosurgery and Psychiatry 93 (Suppl 1), A90-A90, 2022 | 1 | 2022 |