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Lang Pan
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Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation
T Visnes, A Cázares-Körner, W Hao, O Wallner, G Masuyer, O Loseva, ...
Science 362 (6416), 834-839, 2018
1942018
Oxidized guanine base lesions function in 8-oxoguanine DNA glycosylase-1-mediated epigenetic regulation of nuclear factor κB-driven gene expression
L Pan, B Zhu, W Hao, X Zeng, SA Vlahopoulos, TK Hazra, ML Hegde, ...
Journal of Biological Chemistry 291 (49), 25553-25566, 2016
1882016
The roles of base excision repair enzyme OGG1 in gene expression
R Wang, W Hao, L Pan, I Boldogh, X Ba
Cellular and molecular life sciences 75, 3741-3750, 2018
852018
OGG1-DNA interactions facilitate NF-κB binding to DNA targets
L Pan, W Hao, X Zheng, X Zeng, A Ahmed Abbasi, I Boldogh, X Ba
Scientific reports 7 (1), 43297, 2017
642017
Lipopolysaccharide activates ERK–PARP-1–RelA pathway and promotes nuclear factor–κB transcription in murine macrophages
L Liu, Y Ke, X Jiang, F He, L Pan, L Xu, X Zeng, X Ba
Human immunology 73 (5), 439-447, 2012
602012
Effects of the stimuli-dependent enrichment of 8-oxoguanine DNA glycosylase1 on chromatinized DNA
W Hao, T Qi, L Pan, R Wang, B Zhu, L Aguilera-Aguirre, Z Radak, ...
Redox biology 18, 43-53, 2018
562018
Enzymatically inactive OGG1 binds to DNA and steers base excision repair toward gene transcription
W Hao, J Wang, Y Zhang, C Wang, L Xia, W Zhang, M Zafar, JY Kang, ...
The FASEB journal 34 (6), 7427, 2020
412020
Pathophysiology of bronchoconstriction: role of oxidatively damaged DNA repair
A Bacsi, L Pan, X Ba, I Boldogh
Current opinion in allergy and clinical immunology 16 (1), 59-67, 2016
392016
Daidzein suppresses pro-inflammatory chemokine Cxcl2 transcription in TNF-α-stimulated murine lung epithelial cells via depressing PARP-1 activity
H Li, L Pan, Y Ke, E Batnasan, X Jin, Z Liu, X Ba
Acta Pharmacologica Sinica 35 (4), 496-503, 2014
392014
Small-molecule-mediated OGG1 inhibition attenuates pulmonary inflammation and lung fibrosis in a murine lung fibrosis model
L Tanner, AB Single, RKV Bhongir, M Heusel, T Mohanty, CAQ Karlsson, ...
Nature communications 14 (1), 643, 2023
232023
8-Oxoguanine DNA glycosylase1–driven DNA repair—a paradoxical role in lung aging
P German, D Saenz, P Szaniszlo, L Aguilera-Aguirre, L Pan, ML Hegde, ...
Mechanisms of ageing and development 161, 51-65, 2017
212017
Pollen-induced oxidative DNA damage response regulates miRNAs controlling allergic inflammation
L Aguilera-Aguirre, W Hao, L Pan, X Li, A Saavedra-Molina, A Bacsi, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 313 (6 …, 2017
172017
Epigenetic regulation of TIMP1 expression by 8-oxoguanine DNA glycosylase-1 binding to DNA: RNA hybrid
L Pan, H Wang, J Luo, J Zeng, J Pi, H Liu, C Liu, X Ba, X Qu, Y Xiang, ...
The FASEB Journal 33 (12), 14159, 2019
162019
Innate immune responses to RSV infection facilitated by OGG1, an enzyme repairing oxidatively modified DNA base lesions
X Zheng, K Wang, L Pan, W Hao, Y Xue, A Bacsi, SA Vlahopoulos, ...
Journal of innate immunity 14 (6), 593-614, 2022
122022
Pharmacological OGG1 inhibition decreases murine allergic airway inflammation
L Tanner, J Bergwik, RKV Bhongir, L Pan, C Dong, O Wallner, C Kalderén, ...
Frontiers in Pharmacology 13, 999180, 2022
92022
8-Oxoguanine targeted by 8-oxoguanine DNA glycosylase 1 (OGG1) is central to fibrogenic gene activation upon lung injury
L Pan, W Hao, Y Xue, K Wang, X Zheng, J Luo, X Ba, Y Xiang, X Qin, ...
Nucleic acids research 51 (3), 1087-1102, 2023
82023
CTNNAL1 participates in the regulation of mucus overproduction in HDM‐induced asthma mouse model through the YAP‐ROCK2 pathway
D Wu, W Jiang, C Liu, L Liu, F Li, X Ma, L Pan, C Liu, X Qu, H Liu, X Qin, ...
Journal of Cellular and Molecular Medicine 26 (5), 1656-1671, 2022
72022
OGG1 in Lung—More than Base Excision Repair
X Ma, H Ming, L Liu, J Zhu, L Pan, Y Chen, Y Xiang
Antioxidants 11 (5), 933, 2022
62022
Endothelial dysfunction through oxidatively generated epigenetic mark in respiratory viral infections
S Vlahopoulos, K Wang, Y Xue, X Zheng, I Boldogh, L Pan
Cells 10 (11), 3067, 2021
62021
RELA∙ 8-Oxoguanine DNA glycosylase1 is an epigenetic regulatory complex coordinating the hexosamine biosynthetic pathway in RSV infection
X Xu, D Qiao, L Pan, I Boldogh, Y Zhao, AR Brasier
Cells 11 (14), 2210, 2022
52022
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