| Cleavage of Carbon− Carbon Bonds through the Mild Release of Trifluoroacetate: Generation of α, α-Difluoroenolates for Aldol Reactions C Han, EH Kim, DA Colby Journal of the American Chemical Society 133 (15), 5802-5805, 2011 | 168 | 2011 |
| High-affinity small-molecule inhibitors of the menin-mixed lineage leukemia (MLL) interaction closely mimic a natural protein–protein interaction S He, TJ Senter, J Pollock, C Han, SK Upadhyay, T Purohit, RD Gogliotti, ... Journal of medicinal chemistry 57 (4), 1543-1556, 2014 | 113 | 2014 |
| The natural products parthenolide and andrographolide exhibit anti-cancer stem cell activity in multiple myeloma EJ Gunn, JT Williams, DT Huynh, MJ Iannotti, C Han, FJ Barrios, ... Leukemia & lymphoma 52 (6), 1085-1097, 2011 | 101 | 2011 |
| Evaluation of Difluoromethyl Ketones as Agonists of the γ-Aminobutyric Acid Type B (GABAB) Receptor C Han, AE Salyer, EH Kim, X Jiang, RE Jarrard, MS Powers, AM Kirchhoff, ... Journal of Medicinal Chemistry 56 (6), 2456-2465, 2013 | 95 | 2013 |
| Semisynthetic derivatives of sesquiterpene lactones by palladium-catalyzed arylation of the α-methylene-γ-lactone substructure C Han, FJ Barrios, MV Riofski, DA Colby The Journal of Organic Chemistry 74 (18), 7176-7179, 2009 | 75 | 2009 |
| Discovery and optimization of salicylic acid-derived sulfonamide inhibitors of the WD repeat-containing protein 5–MYC protein–protein interaction JD Macdonald, S Chacón Simon, C Han, F Wang, JG Shaw, JE Howes, ... Journal of medicinal chemistry 62 (24), 11232-11259, 2019 | 45 | 2019 |
| Discovery and structure-based optimization of potent and selective WD repeat domain 5 (WDR5) inhibitors containing a dihydroisoquinolinone bicyclic core J Tian, KB Teuscher, ER Aho, JR Alvarado, JJ Mills, KM Meyers, ... Journal of medicinal chemistry 63 (2), 656-675, 2019 | 41 | 2019 |
| Discovery and optimization of a novel series of highly CNS penetrant M4 PAMs based on a 5, 6-dimethyl-4-(piperidin-1-yl) thieno [2, 3-d] pyrimidine core MR Wood, MJ Noetzel, JL Engers, KA Bollinger, BJ Melancon, JC Tarr, ... Bioorganic & medicinal chemistry letters 26 (13), 3029-3033, 2016 | 31 | 2016 |
| Optimization of M4 positive allosteric modulators (PAMs): the discovery of VU0476406, a non-human primate in vivo tool compound for translational pharmacology BJ Melancon, MR Wood, MJ Noetzel, KD Nance, EM Engelberg, C Han, ... Bioorganic & medicinal chemistry letters 27 (11), 2296-2301, 2017 | 28 | 2017 |
| Conversion of methyl ketones and methyl sulfones into α-deutero-α, α-difluoromethyl ketones and α-deutero-α, α-difluoromethyl sulfones in three synthetic steps MF Sowaileh, C Han, RA Hazlitt, EH Kim, JP John, DA Colby Tetrahedron letters 58 (5), 396-400, 2017 | 28 | 2017 |
| Automated detection of acute myocardial infarction using asynchronous electrocardiogram signals—preview of implementing artificial intelligence with multichannel … C Han, Y Song, HS Lim, Y Tae, JH Jang, BT Lee, Y Lee, W Bae, D Yoon Journal of Medical Internet Research 23 (9), e31129, 2021 | 18 | 2021 |
| Discovering hidden information in biosignals from patients using artificial intelligence D Yoon, JH Jang, BJ Choi, TY Kim, CH Han Korean journal of anesthesiology 73 (4), 275, 2020 | 18 | 2020 |
| Stable log surfaces, admissible covers, and canonical curves of genus 4 A Deopurkar, C Han Transactions of the American Mathematical Society 374 (1), 589-641, 2021 | 17 | 2021 |
| Progress towards small molecule menin-mixed lineage leukemia (MLL) interaction inhibitors with in vivo utility T Senter, RD Gogliotti, C Han, CW Locuson, R Morrison, JS Daniels, ... Bioorganic & medicinal chemistry letters 25 (13), 2720-2725, 2015 | 17 | 2015 |
| Arithmetic of the moduli of semistable elliptic surfaces C Han, JY Park Mathematische Annalen 375, 1745-1760, 2019 | 16 | 2019 |
| Discovery and SAR of muscarinic receptor subtype 1 (M1) allosteric activators from a molecular libraries high throughput screen. Part 1: 2, 5-dibenzyl-2H-pyrazolo [4, 3-c … C Han, A Chatterjee, MJ Noetzel, JD Panarese, E Smith, P Chase, ... Bioorganic & medicinal chemistry letters 25 (2), 384-388, 2015 | 12 | 2015 |
| Controlling the Cleavage of Carbon–Carbon Bonds To Generate α, α-Difluorobenzyl Carbanions for the Construction of Difluoromethylbenzenes HR Khatri, C Han, E Luong, X Pan, AT Adam, MD Alshammari, Y Shao, ... The Journal of organic chemistry 84 (18), 11665-11675, 2019 | 10 | 2019 |
| Discovery of Tricyclic Triazolo- and Imidazopyridine Lactams as M1 Positive Allosteric Modulators JL Engers, AM Bender, JJ Kalbfleisch, HP Cho, KS Lingenfelter, ... ACS chemical neuroscience 10 (3), 1035-1042, 2018 | 10 | 2018 |
| Cleaving Carbon–Carbon Bonds by the Release of Trifluoroacetate to Remodel Molecules and Assemble Fluorinated Structures C Han, EH Kim, DA Colby Synlett 23 (11), 1559-1563, 2012 | 10 | 2012 |
| Development of VU6019650: A Potent, Highly Selective, and Systemically Active Orthosteric Antagonist of the M5 Muscarinic Acetylcholine Receptor for the … AT Garrison, DL Orsi, RA Capstick, D Whomble, J Li, TR Carter, AS Felts, ... Journal of Medicinal Chemistry 65 (8), 6273-6286, 2022 | 9 | 2022 |
Craig LindsleyVanderbilt UniversityVerified email at vanderbilt.edu
