| Signal transduction through MAP kinase cascades TS Lewis, PS Shapiro, NG Ahn Advances in cancer research 74, 49-139, 1998 | 2416 | 1998 |
| Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins JA Frost, H Steen, P Shapiro, T Lewis, N Ahn, PE Shaw, MH Cobb The EMBO journal 16 (21), 6426-6438, 1997 | 540 | 1997 |
| Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-β and retinoic acid combination, using a genetic approach JE Angell, DJ Lindner, PS Shapiro, ER Hofmann, DV Kalvakolanu Journal of Biological Chemistry 275 (43), 33416-33426, 2000 | 300 | 2000 |
| Activation of the MKK/ERK pathway during somatic cell mitosis: direct interactions of active ERK with kinetochores and regulation of the mitotic 3F3/2 phosphoantigen PS Shapiro, E Vaisberg, AJ Hunt, NS Tolwinski, AM Whalen, JR McIntosh, ... The Journal of cell biology 142 (6), 1533-1545, 1998 | 281 | 1998 |
| Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase AM Whalen, SC Galasinski, PS Shapiro, TS Nahreini, NG Ahn Molecular and cellular biology, 1997 | 276 | 1997 |
| Targeting the MAPK signaling pathway in cancer: promising preclinical activity with the novel selective ERK1/2 inhibitor BVD-523 (ulixertinib) UA Germann, BF Furey, W Markland, RR Hoover, AM Aronov, JJ Roix, ... Molecular cancer therapeutics 16 (11), 2351-2363, 2017 | 220 | 2017 |
| ERK1 and ERK2 activate CCAAAT/enhancer-binding protein-β-dependent gene transcription in response to interferon-γ J Hu, SK Roy, PS Shapiro, SR Rodig, SPM Reddy, LC Platanias, ... Journal of Biological Chemistry 276 (1), 287-297, 2001 | 211 | 2001 |
| Raf kinase inhibitory protein regulates aurora B kinase and the spindle checkpoint EM Eves, P Shapiro, K Naik, UR Klein, N Trakul, MR Rosner Molecular cell 23 (4), 561-574, 2006 | 202 | 2006 |
| Distinct cell cycle timing requirements for extracellular signal-regulated kinase and phosphoinositide 3-kinase signaling pathways in somatic cell mitosis EC Roberts, PS Shapiro, TS Nahreini, G Pages, J Pouyssegur, NG Ahn Molecular and cellular biology 22 (20), 7226-7241, 2002 | 181 | 2002 |
| Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway M Qiao, P Shapiro, R Kumar, A Passaniti Journal of Biological Chemistry 279 (41), 42709-42718, 2004 | 168 | 2004 |
| Identification of novel extracellular signal-regulated kinase docking domain inhibitors CN Hancock, A Macias, EK Lee, SY Yu, AD MacKerell, P Shapiro Journal of medicinal chemistry 48 (14), 4586-4595, 2005 | 154 | 2005 |
| Ras-MAP kinase signaling pathways and control of cell proliferation: relevance to cancer therapy P Shapiro Critical reviews in clinical laboratory sciences 39 (4-5), 285-330, 2002 | 144 | 2002 |
| The Seven-transmembrane-spanning Receptors for Endothelin and Thrombin Cause Proliferation of Airway Smooth Muscle Cells and Activation of the Extracellular Regulated Kinase … PS Shapiro, JN Evans, RJ Davis, JA Posada Journal of Biological Chemistry 271 (10), 5750-5754, 1996 | 139 | 1996 |
| Extracellular signal-regulated kinase activates topoisomerase IIα through a mechanism independent of phosphorylation PS Shapiro, AM Whalen, NS Tolwinski, J Wilsbacher, SJ Froelich-Ammon, ... Molecular and cellular biology 19 (5), 3551-3560, 1999 | 137 | 1999 |
| MEKK1 plays a critical role in activating the transcription factor C/EBP-β-dependent gene expression in response to IFN-γ SK Roy, J Hu, Q Meng, Y Xia, PS Shapiro, SPM Reddy, LC Platanias, ... Proceedings of the National Academy of Sciences 99 (12), 7945-7950, 2002 | 127 | 2002 |
| Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation M Qiao, P Shapiro, M Fosbrink, H Rus, R Kumar, A Passaniti Journal of biological chemistry 281 (11), 7118-7128, 2006 | 126 | 2006 |
| Involvement of the MAP kinase ERK2 in MUC1 mucin signaling D Meerzaman, PS Shapiro, KC Kim American Journal of Physiology-Lung Cellular and Molecular Physiology 281 (1 …, 2001 | 111 | 2001 |
| Mitochondrial detachment of hexokinase 1 in mood and psychotic disorders: implications for brain energy metabolism and neurotrophic signaling WT Regenold, M Pratt, S Nekkalapu, PS Shapiro, T Kristian, G Fiskum Journal of psychiatric research 46 (1), 95-104, 2012 | 107 | 2012 |
| Nuclear localization of mitogen-activated protein kinase kinase 1 (MKK1) is promoted by serum stimulation and G2-M progression: requirement for phosphorylation at the … NS Tolwinski, PS Shapiro, S Goueli, NG Ahn Journal of Biological Chemistry 274 (10), 6168-6174, 1999 | 100 | 1999 |
| Feedback regulation of Raf-1 and mitogen-activated protein kinase (MAP) kinase kinases 1 and 2 by MAP kinase phosphatase-1 (MKP-1) PS Shapiro, NG Ahn Journal of Biological Chemistry 273 (3), 1788-1793, 1998 | 97 | 1998 |
