Dihydroxyacetone phosphate signals glucose availability to mTORC1 JM Orozco, PA Krawczyk, SM Scaria, AL Cangelosi, SH Chan, T Kunchok, ... Nature metabolism 2 (9), 893-901, 2020 | 161 | 2020 |
Fumarate is a terminal electron acceptor in the mammalian electron transport chain JB Spinelli, PC Rosen, HG Sprenger, AM Puszynska, JL Mann, ... Science 374 (6572), 1227-1237, 2021 | 120 | 2021 |
A nutrient-sensing transition at birth triggers glucose-responsive insulin secretion A Helman, AL Cangelosi, JC Davis, Q Pham, A Rothman, AL Faust, ... Cell metabolism 31 (5), 1004-1016. e5, 2020 | 103 | 2020 |
MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo EC Bayraktar, L Baudrier, C Özerdem, CA Lewis, SH Chan, T Kunchok, ... Proceedings of the National Academy of Sciences 116 (1), 303-312, 2019 | 88 | 2019 |
A long non-coding RNA, lncLGR, regulates hepatic glucokinase expression and glycogen storage during fasting X Ruan, P Li, A Cangelosi, L Yang, H Cao Cell reports 14 (8), 1867-1875, 2016 | 76 | 2016 |
CLN3 is required for the clearance of glycerophosphodiesters from lysosomes NN Laqtom, W Dong, UN Medoh, AL Cangelosi, V Dharamdasani, ... Nature 609 (7929), 1005-1011, 2022 | 46 | 2022 |
Balancing protein stability and activity in cancer: a new approach for identifying driver mutations affecting CBL ubiquitin ligase activation M Li, SC Kales, K Ma, BA Shoemaker, J Crespo-Barreto, AL Cangelosi, ... Cancer research 76 (3), 561-571, 2016 | 35 | 2016 |
Zonated leucine sensing by Sestrin-mTORC1 in the liver controls the response to dietary leucine AL Cangelosi, AM Puszynska, JM Roberts, A Armani, TP Nguyen, ... Science 377 (6601), 47-56, 2022 | 24 | 2022 |
High fat diet and stem cells: Linking diet to intestinal tumor formation AL Cangelosi, ÖH Yilmaz Cell cycle 15 (13), 1657-1658, 2016 | 8 | 2016 |
Dihydroxyacetone phosphate signals glucose availability to mTORC1. Nat. Metab. 2, 893–901 JM Orozco, PA Krawczyk, SM Scaria, AL Cangelosi, SH Chan, T Kunchok, ... | 7 | 2020 |
The Batten disease gene product CLN3 is required for the clearance of glycerophosphodiesters from lysosomes N Laqtom, W Dong, U Medoh, A Cangelosi, V Dharamdasani, SH Chan, ... 2022 AIChE Annual Meeting, 2022 | | 2022 |
Nutrient sensing by the mTORC1 pathway in physiology AL Cangelosi Massachusetts Institute of Technology, 2022 | | 2022 |
A Fasting-induced LncRNA Regulates Hepatic and Systemic Glucose Metabolism X Ruan, P Li, L Yang, A Cangelosi, H Cao DIABETES 64, A501-A502, 2015 | | 2015 |