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Karthik Nathan
Karthik Nathan
Verified email at hss.edu
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Year
Mesenchymal stem cell-macrophage crosstalk and bone healing
J Pajarinen, T Lin, E Gibon, Y Kohno, M Maruyama, K Nathan, L Lu, Z Yao, ...
Biomaterials 196, 80-89, 2019
6782019
Pro‐inflammatory M1 macrophages promote Osteogenesis by mesenchymal stem cells via the COX‐2‐prostaglandin E2 pathway
LY Lu, F Loi, K Nathan, T Lin, J Pajarinen, E Gibon, A Nabeshima, ...
Journal of Orthopaedic Research 35 (11), 2378-2385, 2017
1702017
Inflammation, ageing, and bone regeneration
E Gibon, LY Lu, K Nathan, SB Goodman
Journal of orthopaedic translation 10, 28-35, 2017
1292017
Preconditioning of murine mesenchymal stem cells synergistically enhanced immunomodulation and osteogenesis
T Lin, J Pajarinen, A Nabeshima, L Lu, K Nathan, E Jämsen, Z Yao, ...
Stem cell research & therapy 8 (1), 1-9, 2017
1062017
Precise immunomodulation of the M1 to M2 macrophage transition enhances mesenchymal stem cell osteogenesis and differs by sex
K Nathan, LY Lu, T Lin, J Pajarinen, E Jämsen, JF Huang, ...
Bone & Joint Research 8 (10), 481-488, 2019
662019
Mesenchymal stem cells in the aseptic loosening of total joint replacements
J Pajarinen, T Lin, A Nabeshima, E Jämsen, L Lu, K Nathan, Z Yao, ...
Journal of Biomedical Materials Research Part A 105 (4), 1195-1207, 2017
582017
Establishment of NF-κB sensing and interleukin-4 secreting mesenchymal stromal cells as an “on-demand” drug delivery system to modulate inflammation
T Lin, J Pajarinen, A Nabeshima, L Lu, K Nathan, Z Yao, SB Goodman
Cytotherapy 19 (9), 1025-1034, 2017
532017
NFκB sensing IL‐4 secreting mesenchymal stem cells mitigate the proinflammatory response of macrophages exposed to polyethylene wear particles
T Lin, Y Kohno, JF Huang, M Romero‐Lopez, J Pajarinen, M Maruyama, ...
Journal of Biomedical Materials Research Part A 106 (10), 2744-2752, 2018
342018
Preconditioned or IL4-secreting mesenchymal stem cells enhanced osteogenesis at different stages
T Lin, Y Kohno, JF Huang, M Romero-Lopez, M Maruyama, M Ueno, ...
Tissue Engineering Part A 25 (15-16), 1096-1103, 2019
332019
Trained murine mesenchymal stem cells have anti-inflammatory effect on macrophages, but defective regulation on T-cell proliferation
T Lin, J Pajarinen, Y Kohno, JF Huang, M Maruyama, M Romero-Lopez, ...
The FASEB Journal 33 (3), 4203, 2019
272019
Transplanted interleukin-4--secreting mesenchymal stromal cells show extended survival and increased bone mineral density in the murine femur
T Lin, J Pajarinen, Y Kohno, M Maruyama, M Romero-Lopez, JF Huang, ...
Cytotherapy 20 (8), 1028-1036, 2018
252018
Murine model of progressive orthopedic wear particle-induced chronic inflammation and osteolysis
J Pajarinen, A Nabeshima, T Lin, T Sato, E Gibon, E Jämsen, L Lu, ...
Tissue Engineering Part C: Methods 23 (12), 1003-1011, 2017
222017
Decreased estimated blood loss in lateral trans-psoas versus anterior approach to lumbar interbody fusion for degenerative spondylolisthesis
LH Goodnough, J Koltsov, T Wang, G Xiong, K Nathan, I Cheng
Journal of Spine Surgery 5 (2), 185, 2019
212019
Orthopaedic wear particle‐induced bone loss and exogenous macrophage infiltration is mitigated by local infusion of NF‐κB decoy oligodeoxynucleotide
T Lin, J Pajarinen, A Nabeshima, LA Córdova, F Loi, E Gibon, L Lu, ...
Journal of Biomedical Materials Research Part A 105 (11), 3169-3175, 2017
132017
Effect of Aging on the Macrophage Response to Titanium Particles
E Jämsen, J Pajarinen, T Lin, CW Lo, A Nabeshima, L Lu, K Nathan, ...
Journal of Orthopaedic Research® 38 (2), 405-416, 2020
112020
Treating titanium particle-induced inflammation with genetically modified NF-κB sensing IL-4 secreting or preconditioned mesenchymal stem cells in vitro
Y Kohno, T Lin, J Pajarinen, E Jämsen, M Romero-Lopez, M Maruyama, ...
ACS biomaterials science & engineering 5 (6), 3032-3038, 2019
92019
Osteogenic ability of rat bone marrow concentrate is at least as efficacious as mesenchymal stem cells in vitro
Y Kohno, T Lin, J Pajarinen, M Romero‐Lopez, M Maruyama, JF Huang, ...
Journal of Biomedical Materials Research Part B: Applied Biomaterials 107 (8 …, 2019
72019
Do-Not-Resuscitate status is an independent risk factor for medical complications and mortality among geriatric patients sustaining hip fractures
LC Bosch, K Nathan, LY Lu, ST Campbell, MJ Gardner, JA Bishop
Journal of Clinical Orthopaedics and Trauma 14, 65-68, 2021
32021
Variability in opioid prescribing following fracture fixation: A retrospective cohort analysis
A Fithian, K Nathan, ST Campbell, A Finlay, J Bishop, MJ Gardner
Current Orthopaedic Practice 31 (2), 101-104, 2020
32020
Modulating Innate Inflammatory Reactions in the Application of Orthopedic Biomaterials
T Lin, E Jämsen, L Lu, K Nathan, J Pajarinen, SB Goodman
Orthopedic Biomaterials: Progress in Biology, Manufacturing, and Industry …, 2018
22018
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Articles 1–20