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Manoranjenni Chetty
Manoranjenni Chetty
Simcyp Ltd (a Certara company)
Verified email at simcyp.com
Title
Cited by
Cited by
Year
Pharmacokinetics, pharmacodynamics and physiologically-based pharmacokinetic modelling of monoclonal antibodies
M Dostalek, I Gardner, BM Gurbaxani, RH Rose, M Chetty
Clinical pharmacokinetics 52, 83-124, 2013
2412013
Gender differences in p-glycoprotein expression and function: effects on drug disposition and outcome
M Bebawy, M Chetty
Current drug metabolism 10 (4), 322-328, 2009
862009
Application of a Physiologically Based Pharmacokinetic Model to Predict OATP1B1‐Related Variability in Pharmacodynamics of Rosuvastatin
RH Rose, S Neuhoff, K Abduljalil, M Chetty, A Rostami‐Hodjegan, ...
CPT: pharmacometrics & systems pharmacology 3 (7), 1-9, 2014
792014
Potential sources of inter-subject variability in monoclonal antibody pharmacokinetics
KL Gill, KK Machavaram, RH Rose, M Chetty
Clinical pharmacokinetics 55 (7), 789-805, 2016
762016
CYP-mediated clozapine interactions: how predictable are they?
M Chetty, M Murray
Current drug metabolism 8 (4), 307-313, 2007
642007
Applications of linking PBPK and PD models to predict the impact of genotypic variability, formulation differences, differences in target binding capacity and target site drug …
M Chetty, RH Rose, K Abduljalil, N Patel, G Lu, T Cain, M Jamei, ...
Frontiers in pharmacology 5, 258, 2014
602014
Physiologically based pharmacokinetic modelling to guide drug delivery in older people
M Chetty, TN Johnson, S Polak, F Salem, K Doki, A Rostami-Hodjegan
Advanced Drug Delivery Reviews 135, 85-96, 2018
552018
Impact of CYP polymorphisms, ethnicity and sex differences in metabolism on dosing strategies: the case of efavirenz
P Naidoo, VV Chetty, M Chetty
European journal of clinical pharmacology 70, 379-389, 2014
522014
A high-throughput assay using liquid chromatography-tandem mass spectrometry for simultaneous in vivo phenotyping of 5 major cytochrome p450 enzymes in patients
S Ghassabian, M Chetty, BN Tattam, J Glen, J Rahme, Z Stankovic, ...
Therapeutic drug monitoring 31 (2), 239-246, 2009
482009
Smoking and body weight influence the clearance of chlorpromazine.
M Chetty, R Miller, SV Moodley
European journal of clinical pharmacology 46 (6), 523-526, 1994
481994
Psychotropic drug interactions with valproate
J Fleming, M Chetty
Clinical neuropharmacology 28 (2), 96-101, 2005
472005
Sex differences in the clearance of CYP3A4 substrates: exploring possible reasons for the substrate dependency and lack of consensus
M Chetty, D Mattison, A Rostami-Hodjegan
Current drug metabolism 13 (6), 778-786, 2012
442012
Therapeutic monitoring of valproate in psychiatry: how far have we progressed?
J Fleming, M Chetty
Clinical neuropharmacology 29 (6), 350-360, 2006
392006
Phenytoin auto-induction
M Chetty, R Miller, MA Seymour
Therapeutic drug monitoring 20 (1), 60-62, 1998
311998
Prediction of the pharmacokinetics, pharmacodynamics, and efficacy of a monoclonal antibody, using a physiologically based pharmacokinetic FcRn model
M Chetty, L Li, R Rose, K Machavaram, M Jamei, A Rostami-Hodjegan, ...
Frontiers in Immunology 5, 670, 2015
302015
Differential pharmacological regulation of drug efflux and pharmacoresistant schizophrenia
M Bebawy, M Chetty
Bioessays 30 (2), 183-188, 2008
282008
Are standard doses of renally-excreted antiretrovirals in older patients appropriate: a PBPK study comparing exposures in the elderly population with those in renal impairment
M De Sousa Mendes, M Chetty
Drugs in R&D 19 (4), 339-350, 2019
232019
Are Physiologically Based Pharmacokinetic Models Reporting the Right Cmax? Central Venous Versus Peripheral Sampling Site
H Musther, KL Gill, M Chetty, A Rostami-Hodjegan, M Rowland, M Jamei
The AAPS journal 17, 1268-1279, 2015
202015
Dosing and therapeutic monitoring of phenytoin in young adults after neurotrauma: are current practices relevant?
V Frend, M Chetty
Clinical neuropharmacology 30 (6), 362-369, 2007
202007
The use of a side effect as a qualitative indicator of plasma chlorpromazine levels
M Chetty, E Gouws, R Miller, SV Moodley
European neuropsychopharmacology 9 (1-2), 77-82, 1999
201999
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